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A guide to changing paradigms of glucocorticoid receptor function-a model system for genome regulation and physiology.
The FEBS journal, 289 :5718-5743
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A guide to changing paradigms of glucocorticoid receptor function-a model system for genome regulation and physiology.
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A macrophage-hepatocyte glucocorticoid receptor axis coordinates fasting ketogenesis.
Cell metabolism, 34 :473-486.e9
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A macrophage-hepatocyte glucocorticoid receptor axis coordinates fasting ketogenesis.
Cell metabolism, 34 :473-486.e9
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Bone Mass and Osteoblast Activity Are Sex-Dependent in Mice Lacking the Estrogen Receptor α in Chondrocytes and Osteoblast Progenitor Cells.
International journal of molecular sciences, 23
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Hoffmann,
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Cigarette smoke exposure reduces hemorrhagic shock induced circulatory dysfunction in mice with attenuated glucocorticoid receptor function.
Frontiers in immunology, 13 :980707
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Cigarette smoke exposure reduces hemorrhagic shock induced circulatory dysfunction in mice with attenuated glucocorticoid receptor function.
Frontiers in immunology, 13 :980707
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Köhl,
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Ignatius,
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Complement receptor C5aR1 on osteoblasts regulates osteoclastogenesis in experimental postmenopausal osteoporosis.
Frontiers in endocrinology, 13 :1016057
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Complement receptor C5aR1 on osteoblasts regulates osteoclastogenesis in experimental postmenopausal osteoporosis.
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Mayer,
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Muche,
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Could a phase model help to improve translational animal research?
Animal models and experimental medicine, 5 :550-556
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Could a phase model help to improve translational animal research?
Animal models and experimental medicine, 5 :550-556
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Dexamethasone-mediated inhibition of Notch signalling blocks the interaction of leukaemia and mesenchymal stromal cells.
British journal of haematology, 196 :995-1006
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Dexamethasone-mediated inhibition of Notch signalling blocks the interaction of leukaemia and mesenchymal stromal cells.
British journal of haematology, 196 :995-1006
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Tuckermann,
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Henning,
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Lerner,
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Movérare-Skrtic,
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Estradiol and RSPO3 regulate vertebral trabecular bone mass independent of each other.
American journal of physiology. Endocrinology and metabolism, 322 :E211-E218
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Estradiol and RSPO3 regulate vertebral trabecular bone mass independent of each other.
American journal of physiology. Endocrinology and metabolism, 322 :E211-E218
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Mounier,
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Chazaud,
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Radermacher,
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Fischer-Posovszky,
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Caratti,
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Tuckermann,
Jan
Glucocorticoids coordinate macrophage metabolism through the regulation of the tricarboxylic acid cycle.
Molecular metabolism, 57 :101424
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Glucocorticoids coordinate macrophage metabolism through the regulation of the tricarboxylic acid cycle.
Molecular metabolism, 57 :101424
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185.
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Nandi,
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Chennappan,
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Tuckermann,
Jan P.;
Zenker,
Martin;
Cirstea,
Ion Cristian
Increased osteoclastogenesis contributes to bone loss in the Costello syndrome Hras G12V mouse model.
Frontiers in cell and developmental biology, 10 :1000575
2022
Increased osteoclastogenesis contributes to bone loss in the Costello syndrome Hras G12V mouse model.
Frontiers in cell and developmental biology, 10 :1000575
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Ahmad,
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Inhibition of Cdk5 Ameliorates Skeletal Bone Loss in Glucocorticoid-Treated Mice.
Biomedicines, 10
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Inhibition of Cdk5 Ameliorates Skeletal Bone Loss in Glucocorticoid-Treated Mice.
Biomedicines, 10
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Nandi,
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Yilmaz,
Dilay;
Stolz,
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Tangudu,
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Vázquez,
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Pachmayr,
Johanna;
Cirstea,
Ion Cristian;
Spasic,
Maja Vujic;
Ploubidou,
Aspasia;
Ignatius,
Anita;
Tuckermann,
Jan
Inhibition of Cdk5 increases osteoblast differentiation and bone mass and improves fracture healing.
Bone research, 10 :33
April 2022
Inhibition of Cdk5 increases osteoblast differentiation and bone mass and improves fracture healing.
Bone research, 10 :33
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Meyer Zu Reckendorf,
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Hegler,
Jutta;
Deininger,
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Catanese,
Alberto;
Vettorazzi,
Sabine;
Antoniadis,
Gregor;
Boeckers,
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Knöll,
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Motoneuron-Specific PTEN Deletion in Mice Induces Neuronal Hypertrophy and Also Regeneration after Facial Nerve Injury.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 42 :2474-2491
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Motoneuron-Specific PTEN Deletion in Mice Induces Neuronal Hypertrophy and Also Regeneration after Facial Nerve Injury.
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181.
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Stifel,
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Tuckermann,
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Novel insights into the regulation of cellular catabolic metabolism in macrophages through nuclear receptors.
FEBS letters, 596 :2617-2629
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Novel insights into the regulation of cellular catabolic metabolism in macrophages through nuclear receptors.
FEBS letters, 596 :2617-2629
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180.
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Schoppa,
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Xiangxu;
Ramge,
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Vikman,
Anna;
Fischer,
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Melanie;
Riegger,
Jana;
Tuckermann,
Jan;
Scharffetter-Kochanek,
Karin;
Ignatius,
Anita
Osteoblast lineage Sod2 deficiency leads to an osteoporosis-like phenotype in mice.
Disease models & mechanisms, 15
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Osteoblast lineage Sod2 deficiency leads to an osteoporosis-like phenotype in mice.
Disease models & mechanisms, 15
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179.
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Caratti,
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Melanie;
Kazemitash,
Naser;
Traut,
Rebecca;
Wittig,
Rainer;
Casanova,
Emilio;
Ahmadian,
Mohammad Reza;
Tuckermann,
Jan P.;
Moll,
Herwig P.;
Cirstea,
Ion Cristian
The glucocorticoid receptor associates with RAS complexes to inhibit cell proliferation and tumor growth.
Science signaling, 15 :eabm4452
März 2022
The glucocorticoid receptor associates with RAS complexes to inhibit cell proliferation and tumor growth.
Science signaling, 15 :eabm4452
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178.
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Maity-Kumar,
Gandhari;
Ständer,
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DeAngelis,
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Lee,
Sooyeon;
Molenaar,
Anna;
Becker,
Lore;
Garrett,
Lillian;
Amerie,
Oana V.;
Hoelter,
Sabine M.;
Wurst,
Wolfgang;
Fuchs,
Helmut;
Feuchtinger,
Annette;
Gailus-Durner,
Valerie;
García-Cáceres,
Cristina;
Othman,
Ahmed E.;
Brockmann,
Caroline;
Schöffling,
Vanessa I.;
Beiser,
Katja;
Krude,
Heiko;
Mroz,
Piotr A.;
Hofmann,
Susanna;
Tuckermann,
Jan;
DiMarchi,
Richard D.;
Angelis,
Martin;
Tschöp,
Matthias H.;
Pfluger,
Paul T.;
Müller,
Timo D.
Validation of Mct8/Oatp1c1 dKO mice as a model organism for the Allan-Herndon-Dudley Syndrome.
Molecular metabolism, 66 :101616
Dezember 2022
Validation of Mct8/Oatp1c1 dKO mice as a model organism for the Allan-Herndon-Dudley Syndrome.
Molecular metabolism, 66 :101616
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177.
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Bülow,
Jasmin;
Tuckermann,
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Ignatius,
Anita;
Haffner-Luntzer,
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Correction: Steppe et al. Bone Mass and Osteoblast Activity Are Sex-Dependent in Mice Lacking the Estrogen Receptor α in Chondrocytes and Osteoblast Progenitor Cells. Int. J. Mol. Sci. 2022, 23, 2902.
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Correction: Steppe et al. Bone Mass and Osteoblast Activity Are Sex-Dependent in Mice Lacking the Estrogen Receptor α in Chondrocytes and Osteoblast Progenitor Cells. Int. J. Mol. Sci. 2022, 23, 2902.
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176.
[eng]
Kroon,
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Schilperoort,
Maaike;
In Het Panhuis,
Wietse;
Berg,
Rosa;
Doeselaar,
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Verzijl,
Cristy R. C.;
Trigt,
Nikki;
Mol,
Isabel M.;
Sips,
Hetty H. C. M.;
Heuvel,
Jose K.;
Koorneef,
Lisa L.;
Sluis,
Ronald J.;
Fenzl,
Anna;
Kiefer,
Florian W.;
Vettorazzi,
Sabine;
Tuckermann,
Jan P.;
Biermasz,
Nienke R.;
Meijer,
Onno C.;
Rensen,
Patrick C. N.;
Kooijman,
Sander
A physiological glucocorticoid rhythm is an important regulator of brown adipose tissue function.
Molecular metabolism, 47 :101179
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A physiological glucocorticoid rhythm is an important regulator of brown adipose tissue function.
Molecular metabolism, 47 :101179
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175.
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Barnea-Zohar,
Maayan;
Winograd-Katz,
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Reuven,
Nina;
Roth,
Lee;
Golani,
Ofra;
Stein,
Merle;
Thalji,
Fadi;
Kanaan,
Moien;
Tuckermann,
Jan;
Geiger,
Benjamin;
Elson,
Ari
An SNX10-dependent mechanism downregulates fusion between mature osteoclasts.
Journal of cell science, 134
Mai 2021
An SNX10-dependent mechanism downregulates fusion between mature osteoclasts.
Journal of cell science, 134
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174.
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Nairz,
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Metzendorf,
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Vujic-Spasic,
Maja;
Mitterstiller,
Anna-Maria;
Schroll,
Andrea;
Haschka,
David;
Hoffmann,
Alexander;
Von Raffay,
Laura;
Sparla,
Richard;
Huck,
Christian W.;
Talasz,
Heribert;
Moser,
Patrizia L.;
Muckenthaler,
Martina U.;
Weiss,
Günter
Cell-specific expression of Hfe determines the outcome of Salmonella enterica serovar Typhimurium infection in mice.
Haematologica, 106 :3149-3161
Dezember 2021
Cell-specific expression of Hfe determines the outcome of Salmonella enterica serovar Typhimurium infection in mice.
Haematologica, 106 :3149-3161
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173.
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Pfänder,
Pauline;
Eiers,
Ann-Kathrin;
Burret,
Ute;
Vettorazzi,
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Deletion of Cdk5 in Macrophages Ameliorates Anti-Inflammatory Response during Endotoxemia through Induction of C-Maf and Il-10.
International journal of molecular sciences, 22
September 2021
Deletion of Cdk5 in Macrophages Ameliorates Anti-Inflammatory Response during Endotoxemia through Induction of C-Maf and Il-10.
International journal of molecular sciences, 22
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172.
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Lee,
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Ignatius,
Anita;
Tuckermann,
Jan
Distinct Glucocorticoid Receptor Actions in Bone Homeostasis and Bone Diseases.
Frontiers in endocrinology, 12 :815386
2021
Distinct Glucocorticoid Receptor Actions in Bone Homeostasis and Bone Diseases.
Frontiers in endocrinology, 12 :815386
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171.
[eng]
Tschaffon,
Miriam Eva Angelica;
Fischer,
Verena;
Tuckermann,
Jan;
Ignatius,
Anita;
Haffner-Luntzer,
Melanie
Estrogen Receptor α Signaling in Osteoblasts is Required for Mechanotransduction in Bone Fracture Healing.
Frontiers in bioengineering and biotechnology, 9 :782355
2021
Estrogen Receptor α Signaling in Osteoblasts is Required for Mechanotransduction in Bone Fracture Healing.
Frontiers in bioengineering and biotechnology, 9 :782355
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170.
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Giroud,
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Tsokanos,
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Caratti,
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Khani,
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Jouffe,
Céline;
Vogl,
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Irmler,
Martin;
Glantschnig,
Christina;
Gil-Lozano,
Manuel;
Hass,
Daniela;
Khan,
Asrar Ali;
Garcia,
Marcos Rios;
Mattijssen,
Frits;
Maida,
Adriano;
Tews,
Daniel;
Fischer-Posovszky,
Pamela;
Feuchtinger,
Annette;
Virtanen,
Kirsi A.;
Beckers,
Johannes;
Wabitsch,
Martin;
Uhlenhaut,
Henriette;
Blüher,
Matthias;
Tuckermann,
Jan;
Scheideler,
Marcel;
Bartelt,
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Herzig,
Stephan
HAND2 is a novel obesity-linked adipogenic transcription factor regulated by glucocorticoid signalling.
Diabetologia, 64 :1850-1865
August 2021
HAND2 is a novel obesity-linked adipogenic transcription factor regulated by glucocorticoid signalling.
Diabetologia, 64 :1850-1865
August 2021