119.
[eng] Bartelt, Alexander; Behler-Janbeck, Friederike; Beil, F. Timo; Koehne, Till; Müller, Brigitte; Schmidt, Tobias; Heine, Markus; Ochs, Laura; Yilmaz, Tayfun; Dietrich, Martin; Tuckermann, Jan P.; Amling, Michael; Herz, Joachim; Schinke, Thorsten; Heeren, Joerg; Niemeier, Andreas
Lrp1 in osteoblasts controls osteoclast activity and protects against osteoporosis by limiting PDGF-RANKL signaling.
Bone research, 6 :4
2018
118.
[eng] Hachemi, Yasmine; Rapp, Anna E.; Picke, Ann-Kristin; Weidinger, Gilbert; Ignatius, Anita; Tuckermann, Jan
Molecular mechanisms of glucocorticoids on skeleton and bone regeneration after fracture.
Journal of molecular endocrinology, 61 :R75-R90
Juli 2018
117.
[eng] Ignatius, Anita; Tuckermann, Jan
New horizons for osteoanabolic treatment?
Nature reviews. Endocrinology, 14 :508-509
September 2018
116.
[eng] Scholtysek, Carina; Ipseiz, Natacha; Böhm, Christina; Krishnacoumar, Brenda; Stenzel, Martin; Czerwinski, Tina; Palumbo-Zerr, Katrin; Rothe, Tobias; Weidner, Daniela; Klej, Alexandra; Stoll, Cornelia; Distler, Jörg; Tuckermann, Jan; Herrmann, Martin; Fabry, Ben; Goldmann, Wolfgang H.; Schett, Georg; Kr??nke, Gerhard
NR4A1 Regulates Motility of Osteoclast Precursors and Serves as Target for the Modulation of Systemic Bone Turnover.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 33 :2035-2047
November 2018
115.
[eng] Müller, Christine; Zidek, Laura M.; Ackermann, Tobias; Jong, Tristan; Liu, Peng; Kliche, Verena; Zaini, Mohamad Amr; Kortman, Gertrud; Harkema, Liesbeth; Verbeek, Dineke S.; Tuckermann, Jan P.; Maltzahn, Julia; Bruin, Alain; Guryev, Victor; Wang, Zhao-Qi; Calkhoven, Cornelis F.
Reduced expression of C/EBPβ-LIP extends health and lifespan in mice.
eLife, 7
Juni 2018
114.
[eng] Tangudu, Naveen Kumar; Alan, Betül; Vinchi, Francesca; Wörle, Katharina; Lai, Dilay; Vettorazzi, Sabine; Leopold, Kerstin; Vujić Spasić, Maja
Scavenging Reactive Oxygen Species Production Normalizes Ferroportin Expression and Ameliorates Cellular and Systemic Iron Disbalances in Hemolytic Mouse Model.
Antioxidants & redox signaling, 29 :484-499
August 2018
113.
[eng] Baake, Tina; Jörß, Katharina; Suennemann, Jennifer; Roßmann, Laura; Bohnenberger, Hanibal; Tuckermann, Jan P.; Reichardt, Holger M.; Fischer, Henrike J.; Reichardt, Sybille D.
The glucocorticoid receptor in recipient cells keeps cytokine secretion in acute graft-versus-host disease at bay.
Oncotarget, 9 :15437-15450
März 2018
112.
[eng] Armacki, Milena; Trugenberger, Anna Katharina; Ellwanger, Ann K.; Eiseler, Tim; Schwerdt, Christiane; Bettac, Lucas; Langgartner, Dominik; Azoitei, Ninel; Halbgebauer, Rebecca; Groß, Rüdiger; Barth, Tabea; Lechel, André; Walter, Benjamin M.; Kraus, Johann M.; Wiegreffe, Christoph; Grimm, Johannes; Scheffold, Annika; Schneider, Marlon R.; Peuker, Kenneth; Zeißig, Sebastian; Britsch, Stefan; Rose-John, Stefan; Vettorazzi, Sabine; Wolf, Eckhart; Tannapfel, Andrea; Steinestel, Konrad; Reber, Stefan O.; Walther, Paul; Kestler, Hans A.; Radermacher, Peter; Barth, Thomas Fe; Huber-Lang, Markus; Kleger, Alexander; Seufferlein, Thomas
Thirty-eight-negative kinase 1 mediates trauma-induced intestinal injury and multi-organ failure.
The Journal of clinical investigation, 128 :5056-5072
November 2018
111.
[eng] Picke, Ann-Kristin; Campbell, Graeme M.; Blüher, Matthias; Krügel, Ute; Schmidt, Felix N.; Tsourdi, Elena; Winzer, Maria; Rauner, Martina; Vukicevic, Vladimir; Busse, Björn; Salbach-Hirsch, Juliane; Tuckermann, Jan P.; Simon, Jan C.; Anderegg, Ulf; Hofbauer, Lorenz C.; Saalbach, Anja
Thy-1 (CD90) promotes bone formation and protects against obesity.
Science translational medicine, 10
August 2018
110.
[eng] Javaheri, Tahereh; Kazemi, Zahra; Pencik, Jan; Pham, Ha T. T.; Kauer, Maximilian; Noorizadeh, Rahil; Sax, Barbara; Nivarthi, Harini; Schlederer, Michaela; Maurer, Barbara; Hofbauer, Maximillian; Aryee, Dave N. T.; Wiedner, Marc; Tomazou, Eleni M.; Logan, Malcolm; Hartmann, Christine; Tuckermann, Jan P.; Kenner, Lukas; Mikula, Mario; Dolznig, Helmut; Üren, Aykut; Richter, Günther H.; Grebien, Florian; Kovar, Heinrich; Moriggl, Richard
Correction: Increased survival and cell cycle progression pathways are required for EWS/FLI1-induced malignant transformation.
Juli 2018
109.
[eng] Lai, Dilay; Teng, Feng; Hammad, Seddik; Werle, Julia; Maas, Thorsten; Teufel, Andreas; Muckenthaler, Martina U.; Dooley, Steven; Vujić Spasić, Maja
Hepatic Smad7 overexpression causes severe iron overload in mice.
Februar 2018
108.
[eng] Mueller, Kristina M.; Hartmann, Kerstin; Kaltenecker, Doris; Vettorazzi, Sabine; Bauer, Mandy; Mauser, Lea; Amann, Sabine; Jall, Sigrid; Fischer, Katrin; Esterbauer, Harald; Müller, Timo D.; Tschöp, Matthias H.; Magnes, Christoph; Haybaeck, Johannes; Scherer, Thomas; Bordag, Natalie; Tuckermann, Jan P.; Moriggl, Richard
Adipocyte Glucocorticoid Receptor Deficiency Attenuates Aging- and HFD-Induced Obesity and Impairs the Feeding-Fasting Transition.
Diabetes, 66 :272-286
Februar 2017
107.
[eng] Klaßen, Carina; Karabinskaya, Anna; Dejager, Lien; Vettorazzi, Sabine; Van Moorleghem, Justine; Lühder, Fred; Meijsing, Sebastiaan H.; Tuckermann, Jan P.; Bohnenberger, Hanibal; Libert, Claude; Reichardt, Holger M.
Airway Epithelial Cells Are Crucial Targets of Glucocorticoids in a Mouse Model of Allergic Asthma.
Journal of immunology (Baltimore, Md. : 1950), 199 :48-61
Juli 2017
106.
[eng] Minas, Tsion Zewdu; Surdez, Didier; Javaheri, Tahereh; Tanaka, Miwa; Howarth, Michelle; Kang, Hong-Jun; Han, Jenny; Han, Zhi-Yan; Sax, Barbara; Kream, Barbara E.; Hong, Sung-Hyeok; Çelik, Haydar; Tirode, Franck; Tuckermann, Jan; Toretsky, Jeffrey A.; Kenner, Lukas; Kovar, Heinrich; Lee, Sean; Sweet-Cordero, E. Alejandro; Nakamura, Takuro; Moriggl, Richard; Delattre, Olivier; Üren, Aykut
Combined experience of six independent laboratories attempting to create an Ewing sarcoma mouse model.
Oncotarget, 8 :34141-34163
Mai 2017
105.
[eng] Lunova, Mariia; Schwarz, Peggy; Nuraldeen, Renwar; Levada, Kateryna; Kuscuoglu, Deniz; Stützle, Michael; Vujić Spasić, Maja; Haybaeck, Johannes; Ruchala, Piotr; Jirsa, Milan; Deschemin, Jean-Christophe; Vaulont, Sophie; Trautwein, Christian; Strnad, Pavel
Hepcidin knockout mice spontaneously develop chronic pancreatitis owing to cytoplasmic iron overload in acinar cells.
The Journal of pathology, 241 :104-114
Januar 2017
104.
[eng] Liu, Peng; Lee, Sooyeon; Knoll, Jeanette; Rauch, Alexander; Ostermay, Susanne; Luther, Julia; Malkusch, Nicole; Lerner, Ulf H.; Zaiss, Mario M.; Neven, Mona; Wittig, Rainer; Rauner, Martina; David, Jean-Pierre; Bertolino, Philippe; Zhang, Chang X.; Tuckermann, Jan P.
Loss of menin in osteoblast lineage affects osteocyte-osteoclast crosstalk causing osteoporosis.
Cell death and differentiation, 24 :672-682
April 2017
103.
[eng] Quarta, Carmelo; Clemmensen, Christoffer; Zhu, Zhimeng; Yang, Bin; Joseph, Sini S.; Lutter, Dominik; Yi, Chun-Xia; Graf, Elisabeth; García-Cáceres, Cristina; Legutko, Beata; Fischer, Katrin; Brommage, Robert; Zizzari, Philippe; Franklin, Bernardo S.; Krueger, Martin; Koch, Marco; Vettorazzi, Sabine; Li, Pengyun; Hofmann, Susanna M.; Bakhti, Mostafa; Bastidas-Ponce, Aimée; Lickert, Heiko; Strom, Tim M.; Gailus-Durner, Valerie; Bechmann, Ingo; Perez-Tilve, Diego; Tuckermann, Jan; Angelis, Martin; Sandoval, Darleen; Cota, Daniela; Latz, Eicke; Seeley, Randy J.; Müller, Timo D.; DiMarchi, Richard D.; Finan, Brian; Tschöp, Matthias H.
Molecular Integration of Incretin and Glucocorticoid Action Reverses Immunometabolic Dysfunction and Obesity.
Cell metabolism, 26 :620-632.e6
Oktober 2017
102.
[eng] Galuppo, Paolo; Vettorazzi, Sabine; Hövelmann, Julian; Scholz, Claus-Jürgen; Tuckermann, Jan Peter; Bauersachs, Johann; Fraccarollo, Daniela
The glucocorticoid receptor in monocyte-derived macrophages is critical for cardiac infarct repair and remodeling.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 31 :5122-5132
November 2017
101.
[eng] Conaway, H. Herschel; Henning, Petra; Lie, Anita; Tuckermann, Jan; Lerner, Ulf H.
Activation of dimeric glucocorticoid receptors in osteoclast progenitors potentiates RANKL induced mature osteoclast bone resorbing activity.
Bone, 93 :43-54
Dezember 2016
100.
[eng] Finan, Brian; Clemmensen, Christoffer; Zhu, Zhimeng; Stemmer, Kerstin; Gauthier, Karine; Müller, Luisa; De Angelis, Meri; Moreth, Kristin; Neff, Frauke; Perez-Tilve, Diego; Fischer, Katrin; Lutter, Dominik; Sánchez-Garrido, Miguel A.; Liu, Peng; Tuckermann, Jan; Malehmir, Mohsen; Healy, Marc E.; Weber, Achim; Heikenwalder, Mathias; Jastroch, Martin; Kleinert, Maximilian; Jall, Sigrid; Brandt, Sara; Flamant, Frédéric; Schramm, Karl-Werner; Biebermann, Heike; Döring, Yvonne; Weber, Christian; Habegger, Kirk M.; Keuper, Michaela; Gelfanov, Vasily; Liu, Fa; Köhrle, Josef; Rozman, Jan; Fuchs, Helmut; Gailus-Durner, Valerie; Angelis, Martin; Hofmann, Susanna M.; Yang, Bin; Tschöp, Matthias H.; DiMarchi, Richard; Müller, Timo D.
Chemical Hybridization of Glucagon and Thyroid Hormone Optimizes Therapeutic Impact for Metabolic Disease.
Cell, 167 :843-857.e14
Oktober 2016
99.
[eng] Robert, Olivier; Boujedidi, Hédia; Bigorgne, Amélie; Ferrere, Gladys; Voican, Cosmin Sebastian; Vettorazzi, Sabine; Tuckermann, Jan Peter; Bouchet-Delbos, Laurence; Tran, Thi; Hemon, Patrice; Puchois, Virginie; Dagher, Ibrahim; Douard, Richard; Gaudin, Francoise; Gary-Gouy, Hélène; Capel, Francis; Durand-Gasselin, Ingrid; Prévot, Sophie; Rousset, Sophie; Naveau, Sylvie; Godot, Véronique; Emilie, Dominique; Lombès, Marc; Perlemuter, Gabriel; Cassard, Anne-Marie
Decreased expression of the glucocorticoid receptor-GILZ pathway in Kupffer cells promotes liver inflammation in obese mice.
Journal of hepatology, 64 :916-24
April 2016
98.
[eng] Liu, Peng; Baumgart, Mario; Groth, Marco; Wittmann, Jürgen; Jäck, Hans-Martin; Platzer, Matthias; Tuckermann, Jan P.; Baschant, Ulrike
Dicer ablation in osteoblasts by Runx2 driven cre-loxP recombination affects bone integrity, but not glucocorticoid-induced suppression of bone formation.
Scientific reports, 6 :32112
August 2016
97.
[eng] Barcala Tabarrozzi, Andres E.; Andreone, Luz; Deckers, Julie; Castro, Carla N.; Gimeno, María L.; Ariolfo, Laura; Berguer, Paula M.; Antunica-Noguerol, María; Liberman, Ana C.; Vettorazzi, Sabine; Tuckermann, Jan P.; De Bosscher, Karolien; Perone, Marcelo J.
GR-independent down-modulation on GM-CSF bone marrow-derived dendritic cells by the selective glucocorticoid receptor modulator Compound A.
Scientific reports, 6 :36646
November 2016
96.
[eng] Kroll, Torsten; Schmidt, David; Schwanitz, Georg; Ahmad, Mubashir; Hamann, Jana; Schlosser, Corinne; Lin, Yu-Chieh; Böhm, Konrad J.; Tuckermann, Jan; Ploubidou, Aspasia
High-Content Microscopy Analysis of Subcellular Structures: Assay Development and Application to Focal Adhesion Quantification.
Current protocols in cytometry, 77 :12.43.1-12.43.44
Juli 2016
95.
[eng] Javaheri, Tahereh; Kazemi, Zahra; Pencik, Jan; Pham, Ha Tt; Kauer, Maximilian; Noorizadeh, Rahil; Sax, Barbara; Nivarthi, Harini; Schlederer, Michaela; Maurer, Barbara; Hofbauer, Maximillian; Aryee, Dave Nt; Wiedner, Marc; Tomazou, Eleni M.; Logan, Malcolm; Hartmann, Christine; Tuckermann, Jan P.; Kenner, Lukas; Mikula, Mario; Dolznig, Helmut; Üren, Aykut; Richter, Günther H.; Grebien, Florian; Kovar, Heinrich; Moriggl, Richard
Increased survival and cell cycle progression pathways are required for EWS/FLI1-induced malignant transformation.
Cell death & disease, 7 :e2419
Oktober 2016