SFB 1279 Home

  1. Beitzinger, B., Schmid, R., Jung, C., Tiwary, K., Hermann, P., Jacob, T., Lindén, M., 2024a. Confinement and Polarity Effects on the Peptide Packing Density on Mesoporous Silica Nanoparticles. Langmuir 40, 4294–4305. doi.org/10.1021/acs.langmuir.3c03513
  2. Beitzinger, B., Walther, P., Lindén, M., 2024b. Pore analysis of dendritic mesoporous silica nanoparticles by STEM tomography and nitrogen sorption. Microporous and Mesoporous Materials 378, 113247. doi.org/10.1016/j.micromeso.2024.113247
  3. Bongiovanni, C., Bueno-Levy, H., Posadas Pena, D., Del Bono, I., Miano, C., Boriati, S., Da Pra, S., Sacchi, F., Redaelli, S., Bergen, M., Romaniello, D., Pontis, F., Tassinari, R., Kellerer, L., Petraroia, I., Mazzeschi, M., Lauriola, M., Ventura, C., Heermann, S., Weidinger, G., Tzahor, E., D’Uva, G., 2024. BMP7 promotes cardiomyocyte regeneration in zebrafish and adult mice. Cell Rep 43, 114162. doi.org/10.1016/j.celrep.2024.114162
  4. D’Acunto, E., Muzi, A., Marchese, S., Donnici, L., Chiarini, V., Bucci, F., Pavoni, E., Ferrara, F.F., Cappelletti, M., Arriga, R., Serrao, S.M., Peluzzi, V., Principato, E., Compagnone, M., Pinto, E., Luberto, L., Stoppoloni, D., Lahm, A., Groß, R., Seidel, A., Wettstein, L., Münch, J., Goodhead, A., Parisot, J., De Francesco, R., Ciliberto, G., Marra, E., Aurisicchio, L., Roscilli, G., 2024. Isolation and Characterization of Neutralizing Monoclonal Antibodies from a Large Panel of Murine Antibodies against RBD of the SARS-CoV-2 Spike Protein. Antibodies 13, 5. doi.org/10.3390/antib13010005
  5. Fiedler, R., Sivakumaran, G., Mallén, J., Lindén, M., 2024. Superparamagnetic Core–Mesoporous Silica Shell Nanoparticles with Tunable Extra- and Intracellular Dissolution Rates. Chem. Mater. doi.org/10.1021/acs.chemmater.3c02986
  6. Freisem, D., Rodriguez-Alfonso, A.A., Lawrenz, J., Zhou, Z., Monecke, T., Preising, N., Endres, S., Wiese, S., Ständker, L., Kuan, S.-L., Thal, D.R., Weil, T., Niessing, D., Barth, H., Kirchhoff, F., Harms, M., Münch, J., Sparrer, K.M.J., 2024. A naturally occurring 22-amino acid fragment of human hemoglobin A inhibits autophagy and HIV-1. Cell Mol Life Sci 81, 409. doi.org/10.1007/s00018-024-05447-1
  7. Groß, R., Reßin, H., von Maltitz, P., Albers, D., Schneider, L., Bley, H., Hoffmann, M., Cortese, M., Gupta, D., Deniz, M., Choi, J.-Y., Jansen, J., Preußer, C., Seehafer, K., Pöhlmann, S., Voelker, D.R., Goffinet, C., Pogge-von Strandmann, E., Bunz, U., Bartenschlager, R., El Andaloussi, S., Sparrer, K.M.J., Herker, E., Becker, S., Kirchhoff, F., Münch, J., Müller, J.A., 2024. Phosphatidylserine-exposing extracellular vesicles in body fluids are an innate defence against apoptotic mimicry viral pathogens. Nat Microbiol 9, 905–921. doi.org/10.1038/s41564-024-01637-6
  8. Harms, M., Haase, A., Rodríguez-Alfonso, A., Löffler, J., Almeida-Hernández, Y., Ruiz-Blanco, Y.B., Albers, D., Gilg, A., von Bank, F., Zech, F., Groß, R., Datta, M., Jaikishan, J., Draphoen, B., Habib, M., Ständker, L., Wiese, S., Lindén, M., Winter, G., Rasche, V., Beer, A.J., Jumaa, H., Abadi, A.H., Kirchhoff, F., Busch, M., Dünker, N., Sanchez-Garcia, E., Münch, J., 2024. Fatty acid conjugated EPI-X4 derivatives with increased activity and in vivo stability. Journal of Controlled Release 373, 583–598. doi.org/10.1016/j.jconrel.2024.07.049
  9. Hayn, M., John, T., Bandak, J., Rauch-Wirth, L., Abel, B., Münch, J., 2024. Hybrid Materials From Peptide Nanofibrils and Magnetic Beads to Concentrate and Isolate Virus Particles. Advanced Functional Materials n/a, 2316260. doi.org/10.1002/adfm.202316260
  10. Herrmann, A., Gege, C., Wangen, C., Wagner, S., Kögler, M., Cordsmeier, A., Irrgang, P., Ip, W.-H., Weil, T., Hunszinger, V., Groß, R., Heinen, N., Pfaender, S., Reuter, S., Klopfleisch, R., Uhlig, N., Eberlein, V., Issmail, L., Grunwald, T., Hietel, B., Cynis, H., Münch, J., Sparrer, K.M.J., Ensser, A., Tenbusch, M., Dobner, T., Vitt, D., Kohlhof, H., Hahn, F., 2024. Orally bioavailable RORγ/DHODH dual host-targeting small molecules with broad-spectrum antiviral activity. Antiviral Res 231, 106008. doi.org/10.1016/j.antiviral.2024.106008
  11. Hoenigsperger, H., Sivarajan, R., Sparrer, K.M., 2024. Differences and similarities between innate immune evasion strategies of human coronaviruses. Current Opinion in Microbiology 79, 102466. doi.org/10.1016/j.mib.2024.102466
  12. Hoffmann, M., Kleine-Weber, H., Graichen, L., Nehlmeier, I., Kempf, A., Moldenhauer, A.-S., Braun, E., Assiri, A.M., Kirchhoff, F., Sauter, D., Alkharsah, K.R., Pöhlmann, S., 2024. Acquisition of a multibasic cleavage site does not increase MERS-CoV entry into Calu-3 human lung cells. J Virol 98, e0130524. doi.org/10.1128/jvi.01305-24
  13. Klute, S., Sparrer, K.M.J., 2024. Friends and Foes: The Ambivalent Role of Autophagy in HIV-1 Infection. Viruses 16, 500. doi.org/10.3390/v16040500
  14. Kmiec, D., Kirchhoff, F., 2024. Antiviral factors and their counteraction by HIV-1: many uncovered and more to be discovered. Journal of Molecular Cell Biology 16, mjae005. doi.org/10.1093/jmcb/mjae005
  15. Lietz, S., Sokolowski, L.-M., Barth, H., Ernst, K., 2024a. Alpha-1 antitrypsin inhibits Clostridium botulinum C2 toxin, Corynebacterium diphtheriae diphtheria toxin and B. anthracis fusion toxin. Sci Rep 14, 21257. doi.org/10.1038/s41598-024-71706-7
  16. Lietz, S., Sommer, A., Sokolowski, L.-M., Kling, C., Alfonso, A.A.R., Preising, N., Alpízar-Pedraza, D., King, J., Streit, L., Schröppel, B., Erp, R. van, Barth, E., Schneider, M., Münch, J., Michaelis, J., Ständker, L., Wiese, S., Barth, H., Pulliainen, A.T., Scanlon, K., Ernst, K., 2024b. Alpha-1 antitrypsin inhibits pertussis toxin. Journal of Biological Chemistry 300. doi.org/10.1016/j.jbc.2024.107950
  17. Lu, Q., Vosberg, B., Wang, Z., Balasubramanian, P., Sow, M., Volkert, C., Gonzalez Brouwer, R., Lieberwirth, I., Graf, R., Jelezko, F., Plenio, M.B., Wu, Y., Weil, T., 2024. Unraveling Eumelanin Radical Formation by Nanodiamond Optical Relaxometry in a Living Cell. J. Am. Chem. Soc. 146, 7222–7232. doi.org/10.1021/jacs.3c07720
  18. Maier, F.I., Klinger, D., Grieshober, M., Noschka, R., Rodriguez, A., Wiese, S., Forssmann, W.-G., Ständker, L., Stenger, S., 2024. Lysozyme: an endogenous antimicrobial protein with potent activity against extracellular, but not intracellular Mycobacterium tuberculosis. Med Microbiol Immunol 213, 9. doi.org/10.1007/s00430-024-00793-0
  19. Mildenberger, V., Alpízar-Pedraza, D., Martell-Huguet, E.M., Krämer, M., Bolotnikov, G., Otero-Gonzalez, A.J., Weil, T., Rodriguez-Alfonso, A., Preising, N., Ständker, L., Vogel, V., Spellerberg, B., Kissmann, A.-K., Rosenau, F., 2024. The Designed Pore-Forming Antimicrobial Peptide C14R Combines Excellent Activity against the Major Opportunistic Human Pathogen Pseudomonas aeruginosa with Low Cytotoxicity. Pharmaceuticals (Basel) 17, 83. doi.org/10.3390/ph17010083
  20. Pohl, J., Litz, A., El Ayoubi, O., Rodríguez-Alfonso, A., Ständker, L., Harms, M., Münch, J., Jumaa, H., Datta, M., 2024. An Optimized Peptide Antagonist of CXCR4 Limits Survival of BCR–ABL1-Transformed Cells in Philadelphia-Chromosome-Positive B-Cell Acute Lymphoblastic Leukemia. International Journal of Molecular Sciences 25, 8306. doi.org/10.3390/ijms25158306
  21. Prelli Bozzo, C., Laliberté, A., De Luna, A., Pastorio, C., Regensburger, K., Krebs, S., Graf, A., Blum, H., Volcic, M., Sparrer, K.M.J., Kirchhoff, F., 2024. Replication competent HIV-guided CRISPR screen identifies antiviral factors including targets of the accessory protein Nef. Nat Commun 15, 3813. doi.org/10.1038/s41467-024-48228-x
  22. Rajpal, S., Batista, A.D., Groß, R., Münch, J., Mizaikoff, B., Mishra, P., 2024. Rational design based on multi-monomer simultaneous docking for epitope imprinting of SARS-CoV-2 spike protein. Sci Rep 14, 23057. doi.org/10.1038/s41598-024-73114-3
  23. Richard, J., Sannier, G., Zhu, L., Prévost, J., Marchitto, L., Benlarbi, M., Beaudoin-Bussières, G., Kim, H., Sun, Y., Chatterjee, D., Medjahed, H., Bourassa, C., Delgado, G.-G., Dubé, M., Kirchhoff, F., Hahn, B.H., Kumar, P., Kaufmann, D.E., Finzi, A., 2024. CD4 downregulation precedes Env expression and protects HIV-1-infected cells from ADCC mediated by non-neutralizing antibodies. mBio 15, e0182724. doi.org/10.1128/mbio.01827-24
  24. Sauter, D., Kirchhoff, F., 2024. Antiviral mechanisms of guanylate-binding protein 5: versatile inhibition of multiple viral glycoproteins. mBio 15, e02374-24. doi.org/10.1128/mbio.02374-24
  25. Schauenburg, D., Gao, B., Rochet, L.N.C., Schüler, D., Coelho, J.A.S., Ng, D.Y.W., Chudasama, V., Kuan, S.L., Weil, T., 2024. Macrocyclic Dual-Locked “Turn-On” Drug for Selective and Traceless Release in Cancer Cells. Angew Chem Int Ed Engl 63, e202314143. doi.org/10.1002/anie.202314143
  26. Schauenburg, D., Weil, T., 2024. Chemical Reactions in Living Systems. Advanced Science 11, 2303396. doi.org/10.1002/advs.202303396
  27. Tissino, E., Gaglio, A., Nicolò, A., Pozzo, F., Bittolo, T., Rossi, F.M., Bomben, R., Nanni, P., Cattarossi, I., Zaina, E., Zimbo, A.M., Ianna, G., Capasso, G., Forestieri, G., Moia, R., Datta, M., Härzschel, A., Olivieri, J., D’Arena, G., Laurenti, L., Zaja, F., Chiarenza, A., Palumbo, G.A., Martino, E.A., Gentile, M., Rossi, D., Gaidano, G., Del Poeta, G., Laureana, R., Del Principe, M.I., Maity, P.C., Jumaa, H., Hartmann, T.N., Zucchetto, A., Gattei, V., 2024. The VLA-4 integrin is constitutively active in circulating chronic lymphocytic leukemia cells via BCR autonomous signaling: a novel anchor-independent mechanism exploiting soluble blood-borne ligands. Leukemia 38, 2127–2140. doi.org/10.1038/s41375-024-02376-7
  28. Vlachou, A., Nchioua, R., Regensburger, K., Kirchhoff, F., Kmiec, D., 2024. A Gaussia luciferase reporter assay for the evaluation of coronavirus Nsp5/3CLpro activity. Sci Rep 14, 20697. doi.org/10.1038/s41598-024-71305-6
  29. Volcic, M., Nchioua, R., Pastorio, C., Zech, F., Haußmann, I., Sauter, D., Read, C., Walther, P., Kirchhoff, F., 2024. Attenuated replication and damaging effects of SARS-CoV-2 Omicron variants in an intestinal epithelial barrier model. J Med Virol 96, e29783. doi.org/10.1002/jmv.29783
  30. von Maltitz, P., Wettstein, L., Weil, T., Schommers, P., Klein, F., Münch, J., 2024. Semen enhances transmitted/founder HIV-1 infection and only marginally reduces antiviral activity of broadly neutralizing antibodies. Journal of Virology 0, e01190-23. doi.org/10.1128/jvi.01190-23
  31. Wu, K., Lu, Q., Sow, M., Balasubramanian, P., Jelezko, F., Weil, T., Wu, Y., 2024. Nanoscale detection and real-time monitoring of free radicals in a single living cell under the stimulation of targeting moieties using a nanodiamond quantum sensor. Functional Diamond 4, 2336524. doi.org/10.1080/26941112.2024.2336524
  32. Yang, W., Wang, H., Li, Z., Zhang, L., Liu, J., Kirchhoff, F., Huan, C., Zhang, W., 2024. RPLP1 restricts HIV-1 transcription by disrupting C/EBPβ binding to the LTR. Nat Commun 15, 5290. doi.org/10.1038/s41467-024-49622-1
  33. Yin, K., Peluso, M.J., Luo, X., Thomas, R., Shin, M.-G., Neidleman, J., Andrew, A., Young, K.C., Ma, T., Hoh, R., Anglin, K., Huang, B., Argueta, U., Lopez, M., Valdivieso, D., Asare, K., Deveau, T.-M., Munter, S.E., Ibrahim, R., Ständker, L., Lu, S., Goldberg, S.A., Lee, S.A., Lynch, K.L., Kelly, J.D., Martin, J.N., Münch, J., Deeks, S.G., Henrich, T.J., Roan, N.R., 2024. Long COVID manifests with T cell dysregulation, inflammation and an uncoordinated adaptive immune response to SARS-CoV-2. Nat Immunol 25, 218–225. doi.org/10.1038/s41590-023-01724-6
  34. Zech, F., Jung, C., Jacob, T., Kirchhoff, F., 2024. Causes and Consequences of Coronavirus Spike Protein Variability. Viruses 16, 177. doi.org/10.3390/v16020177
  35. Zumwinkel, M., Chirambo, A., Zähnle, M., Bürger, M., Grieshober, M., Romahn, V., Mwandumba, H., Stenger, S., 2024. Polycytotoxic T cells mediate antimicrobial activity against intracellular Mycobacterium tuberculosis. Infection and Immunity 0, e00297-24. doi.org/10.1128/iai.00297-24
     
  1. Amann, V., Kissmann, A.-K., Mildenberger, V., Krebs, I., Perez-Erviti, J.A., Martell-Huguet, E.M., Otero-Gonzalez, A.J., Morales-Vicente, F., Rodríguez-Castaño, G.P., Firacative, C., Rodríguez, A., Ständker, L., Weil, T., Spellerberg, B., Stenger, S., Rosenau, F., 2023. Cm-p5 Peptide Dimers Inhibit Biofilms of Candida albicans Clinical Isolates, C. parapsilosis and Fluconazole-Resistant Mutants of C. auris. Int J Mol Sci 24, 9788. doi.org/10.3390/ijms24129788
  2. Engler, M., Albers, D., Maltitz, P.V., Groß, R., Münch, J., Cirstea, I.C., 2023. ACE2-EGFR-MAPK signaling contributes to SARS-CoV-2 infection. Life Science Alliance 6. doi.org/10.26508/lsa.202201880
  3. Gagiannis, D., Hackenbroch, C., Bloch, W., Zech, F., Kirchhoff, F., Djudjaj, S., Von Stillfried, S., Bülow, R., Boor, P., Steinestel, K., 2023. Clinical, Imaging, and Histopathological Features of Pulmonary Sequelae after Mild COVID-19. Am J Respir Crit Care Med 208, 618–621. doi.org/10.1164/rccm.202302-0285LE
  4. Gaonkar, R.H., Schmidt, Y.T., Mansi, R., Almeida-Hernandez, Y., Sanchez-Garcia, E., Harms, M., Münch, J., Fani, M., 2023. Development of a New Class of CXCR4-Targeting Radioligands Based on the Endogenous Antagonist EPI-X4 for Oncological Applications. J. Med. Chem. 66, 8484–8497. doi.org/10.1021/acs.jmedchem.3c00131
  5. Geretz, A., Ehrenberg, P.K., Clifford, R.J., Laliberté, A., Prelli Bozzo, C., Eiser, D., Kundu, G., Yum, L.K., Apps, R., Creegan, M., Gunady, M., Shangguan, S., Sanders-Buell, E., Sacdalan, C., Phanuphak, N., Tovanabutra, S., Russell, R.M., Bibollet-Ruche, F., Robb, M.L., Michael, N.L., Ake, J.A., Vasan, S., Hsu, D.C., Hahn, B.H., Kirchhoff, F., Thomas, R., 2023. Single-cell transcriptomics identifies prothymosin α restriction of HIV-1 in vivo. Sci. Transl. Med. 15, eadg0873. doi.org/10.1126/scitranslmed.adg0873
  6. Gierse, M., Nagel, L., Keim, M., Lucas, S., Speidel, T., Lobmeyer, T., Winter, G., Josten, F., Karaali, S., Fellermann, M., Scheuer, J., Müller, C., van Heijster, F., Skinner, J., Löffler, J., Parker, A., Handwerker, J., Marshall, A., Salhov, A., El-Kassem, B., Vassiliou, C., Blanchard, J.W., Picazo-Frutos, R., Eills, J., Barth, H., Jelezko, F., Rasche, V., Schilling, F., Schwartz, I., Knecht, S., 2023. Parahydrogen-Polarized Fumarate for Preclinical in Vivo Metabolic Magnetic Resonance Imaging. J. Am. Chem. Soc. 145, 5960–5969. doi.org/10.1021/jacs.2c13830
  7. Hagelauer, E., Lotke, R., Kmiec, D., Hu, D., Hohner, M., Stopper, S., Nchioua, R., Kirchhoff, F., Sauter, D., Schindler, M., 2023. Tetherin Restricts SARS-CoV-2 despite the Presence of Multiple Viral Antagonists. Viruses 15, 2364. doi.org/10.3390/v15122364
  8. Harms, M., Fabech Hansson, R., Gilg, A., Almeida-Hernández, Y., Löffler, J., Rodríguez-Alfonso, A., Habib, M.M.W., Albers, D., Ahmed, N.S., Abadi, A.H., Winter, G., Rasche, V., Beer, A.J., Weidinger, G., Preising, N., Ständker, L., Wiese, S., Sanchez-Garcia, E., Zelikin, A.N., Münch, J., 2023a. Development of N-Terminally Modified Variants of the CXCR4-Antagonistic Peptide EPI-X4 for Enhanced Plasma Stability. J. Med. Chem. 66, 15189–15204. doi.org/10.1021/acs.jmedchem.3c01128
  9. Harms, M., Smith, N., Han, M., Groß, R., von Maltitz, P., Stürzel, C., Ruiz-Blanco, Y.B., Almeida-Hernández, Y., Rodriguez-Alfonso, A., Cathelin, D., Caspar, B., Tahar, B., Sayettat, S., Bekaddour, N., Vanshylla, K., Kleipass, F., Wiese, S., Ständker, L., Klein, F., Lagane, B., Boonen, A., Schols, D., Benichou, S., Sanchez-Garcia, E., Herbeuval, J.-P., Münch, J., 2023b. Spermine and spermidine bind CXCR4 and inhibit CXCR4- but not CCR5-tropic HIV-1 infection. Science Advances 9, eadf8251. doi.org/10.1126/sciadv.adf8251
  10. Heber, S., Borho, J., Stadler, N., Wondany, F., König, I., Michaelis, J., Papatheodorou, P., Barth, H., Fellermann, M., 2023. The Clostridium botulinum C2 Toxin Subunit C2IIa Delivers Enzymes with Positively Charged N-Termini into the Cytosol of Target Cells. Toxins (Basel) 15, 390. doi.org/10.3390/toxins15060390
  11. Heerde, T., Bansal, A., Schmidt, M., Fändrich, M., 2023a. Cryo-EM structure of a catalytic amyloid fibril. Sci Rep 13, 4070. doi.org/10.1038/s41598-023-30711-y
  12. Heerde, T., Schütz, D., Lin, Y.-J., Münch, J., Schmidt, M., Fändrich, M., 2023b. Cryo-EM structure and polymorphic maturation of a viral transduction enhancing amyloid fibril. Nat Commun 14, 4293. doi.org/10.1038/s41467-023-40042-1
  13. Hilbrig, C., Löffler, J., Fischer, G., Scheidhauer, E., Solbach, C., Huber-Lang, M., Beer, A.J., Rasche, V., Winter, G., 2023. Evaluation of the EPR Effect in the CAM-Model by Molecular Imaging with MRI and PET Using 89Zr-Labeled HSA. Cancers 15, 1126. doi.org/10.3390/cancers15041126
  14. Hirschenberger, M., Lepelley, A., Rupp, U., Klute, S., Hunszinger, V., Koepke, L., Merold, V., Didry-Barca, B., Wondany, F., Bergner, T., Moreau, T., Rodero, M.P., Rösler, R., Wiese, S., Volpi, S., Gattorno, M., Papa, R., Lynch, S.-A., Haug, M.G., Houge, G., Wigby, K.M., Sprague, J., Lenberg, J., Read, C., Walther, P., Michaelis, J., Kirchhoff, F., de Oliveira Mann, C.C., Crow, Y.J., Sparrer, K.M.J., 2023. ARF1 prevents aberrant type I interferon induction by regulating STING activation and recycling. Nat Commun 14, 6770. doi.org/10.1038/s41467-023-42150-4
  15. Hoenigsperger, H., Koepke, L., Acharya, D., Hunszinger, V., Freisem, D., Grenzner, A., Wiese, S., Kirchhoff, F., Gack, M.U., Sparrer, K.M.J., 2023. CSNK2 suppresses autophagy by activating FLN-NHL-containing TRIM proteins. Autophagy 0, 1–21. doi.org/10.1080/15548627.2023.2281128
  16. IRF4 International Consortium, Fornes, O., Jia, A., Kuehn, H.S., Min, Q., Pannicke, U., Schleussner, N., Thouenon, R., Yu, Z., De Los Angeles Astbury, M., Biggs, C.M., Galicchio, M., Garcia-Campos, J.A., Gismondi, S., Gonzalez Villarreal, G., Hildebrand, K.J., Hönig, M., Hou, J., Moshous, D., Pittaluga, S., Qian, X., Rozmus, J., Schulz, A.S., Staines-Boone, A.T., Sun, B., Sun, J., Uwe, S., Venegas-Montoya, E., Wang, W., Wang, X., Ying, W., Zhai, X., Zhou, Q., Akalin, A., André, I., Barth, T.F.E., Baumann, B., Brüstle, A., Burgio, G., Bustamante, J.C., Casanova, J.-L., Casarotto, M.G., Cavazzana, M., Chentout, L., Cockburn, I.A., Costanza, M., Cui, C., Daumke, O., Del Bel, K.L., Eibel, H., Feng, X., Franke, V., Gebhardt, J.C.M., Götz, A., Grunwald, S., Hoareau, B., Hughes, T.R., Jacobsen, E.-M., Janz, M., Jolma, A., Lagresle-Peyrou, C., Lai, N., Li, Y., Lin, S., Lu, H.Y., Lugo-Reyes, S.O., Meng, X., Möller, P., Moreno-Corona, N., Niemela, J.E., Novakovsky, G., Perez-Caraballo, J.J., Picard, C., Poggi, L., Puig-Lombardi, M.-E., Randall, K.L., Reisser, A., Schmitt, Y., Seneviratne, S., Sharma, M., Stoddard, J., Sundararaj, S., Sutton, H., Tran, L.Q., Wang, Y., Wasserman, W.W., Wen, Z., Winkler, W., Xiong, E., Yang, A.W.H., Yu, M., Zhang, L., Zhang, H., Zhao, Q., Zhen, X., Enders, A., Kracker, S., Martinez-Barricarte, R., Mathas, S., Rosenzweig, S.D., Schwarz, K., Turvey, S.E., Wang, J.-Y., 2023. A multimorphic mutation in IRF4 causes human autosomal dominant combined immunodeficiency. Sci. Immunol. 8, eade7953. doi.org/10.1126/sciimmunol.ade7953
  17. Janjua, T.I., Cao, Y., Kleitz, F., Linden, M., Yu, C., Popat, A., 2023. Silica nanoparticles: A review of their safety and current strategies to overcome biological barriers. Advanced Drug Delivery Reviews 203, 115115. doi.org/10.1016/j.addr.2023.115115
  18. Kaygisiz, K., Dutta, A., Rauch-Wirth, L., V. Synatschke, C., Münch, J., Bereau, T., Weil, T., 2023a. Inverse design of viral infectivity-enhancing peptide fibrils from continuous protein-vector embeddings. Biomaterials Science 11, 5251–5261. doi.org/10.1039/D3BM00412K
  19. Kaygisiz, K., Ender, A.M., Gačanin, J., Kaczmarek, L.A., Koutsouras, D.A., Nalakath, A.N., Winterwerber, P., Mayer, F.J., Räder, H.-J., Marszalek, T., Blom, P.W.M., Synatschke, C.V., Weil, T., 2023b. Photoinduced Amyloid Fibril Degradation for Controlled Cell Patterning. Macromolecular Bioscience 23, 2200294. doi.org/10.1002/mabi.202200294
  20. Kaygisiz, K., Rauch-Wirth, L., Dutta, A., Yu, X., Nagata, Y., Bereau, T., Münch, J., Synatschke, C.V., Weil, T., 2023c. Data-mining unveils structure–property–activity correlation of viral infectivity enhancing self-assembling peptides. Nat Commun 14, 5121. doi.org/10.1038/s41467-023-40663-6
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