The need for more flexiblity of process-aware information systems (PAIS) has been discussed for several years and different approaches for adaptive process management have emerged. Only few of them provide support for both changes of individual process instances and the propagation of process type changes to a collection of related process instances. The knowledge about changes has not yet been exploited by any of these systems. To overcome this practical limitation, PAIS must capture the whole process life cycle and all kinds of changes in an integrated way. They must allow users to deviate from the predefined process in exceptional situations, and assist them in retrieving and reusing knowledge about previously performed changes. If similar instance deviations occur frequently, process engineers should be supported in deriving improved process models from them. This, in turn, allows them to evolve the PAIS over time as well as the knowledge about the changes. In ProCycle we develop a next generation PAIS, which provides integrated and seamless process life cycle support. ProCycle combines the ADEPT2 framework for dynamic process changes with concepts and methods provided by case-based reasoning (CBR) technology like CBRFlow.