Bioinformatics

Idea: In this experiment we identify and characterize proteins from short peptide sequences
using computational databases

Biophysics Lab Course, Institute of Biophysics, Ulm University

Overview

Online algorithms like BLAST, FASTA etc. are utilized to identify a protein from two short peptide fragments.

The proteomics tools of the ExPASy portal are used to explore the biochemical characteristics of the target protein.

The 3D structure of the protein is downloaded from the PDB and viewed with molecular visualization programmes such as Chimera.

ClustalOmega and Consurf tools are used to analyse homology information and find evolutionary relations for the protein of interest.