194.
[eng] Vettorazzi, Sabine; Nalbantoglu, Denis; Gebhardt, J. Christof M.; Tuckermann, Jan
A guide to changing paradigms of glucocorticoid receptor function-a model system for genome regulation and physiology.
The FEBS journal, 289 :5718-5743
October 2022
193.
[eng] Loft, Anne; Schmidt, Søren Fisker; Caratti, Giorgio; Stifel, Ulrich; Havelund, Jesper; Sekar, Revathi; Kwon, Yun; Sulaj, Alba; Chow, Kan Kau; Alfaro, Ana Jimena; Schwarzmayr, Thomas; Rittig, Nikolaj; Svart, Mads; Tsokanos, Foivos-Filippos; Maida, Adriano; Blutke, Andreas; Feuchtinger, Annette; Møller, Niels; Blüher, Matthias; Nawroth, Peter; Szendrödi, Julia; Færgeman, Nils J.; Zeigerer, Anja; Tuckermann, Jan; Herzig, Stephan
A macrophage-hepatocyte glucocorticoid receptor axis coordinates fasting ketogenesis.
Cell metabolism, 34 :473-486.e9
March 2022
192.
[eng] Bülow, Jasmin; Tuckermann, Jan; Ignatius, Anita; Haffner-Luntzer, Melanie
Bone Mass and Osteoblast Activity Are Sex-Dependent in Mice Lacking the Estrogen Receptor α in Chondrocytes and Osteoblast Progenitor Cells.
International journal of molecular sciences, 23
March 2022
191.
[eng] Wepler, Martin; Preuss, Jonathan M.; Tilp, Cornelia; Keck, Martina; Blender, Jochen; Wachter, Ulrich; Merz, Tamara; Vogt, Josef; Kress, Sandra; Gröger, Michael; Hoffmann, Andrea; Fink, Marina; Calzia, Enrico; Burret, Ute; Radermacher, Peter; Tuckermann, Jan P.; Vettorazzi, Sabine
Cigarette smoke exposure reduces hemorrhagic shock induced circulatory dysfunction in mice with attenuated glucocorticoid receptor function.
Frontiers in immunology, 13 :980707
2022
190.
[eng] Bülow, Jasmin Maria; Renz, Nikolai; Haffner-Luntzer, Melanie; Fischer, Verena; Schoppa, Astrid; Tuckermann, Jan; Köhl, Jörg; Huber-Lang, Markus; Ignatius, Anita
Complement receptor C5aR1 on osteoblasts regulates osteoclastogenesis in experimental postmenopausal osteoporosis.
Frontiers in endocrinology, 13 :1016057
2022
189.
[eng] Mayer, Benjamin; Tuckermann, Jan; Muche, Rainer
Could a phase model help to improve translational animal research?
Animal models and experimental medicine, 5 :550-556
December 2022
188.
[eng] Ahmed, Helal Mohammed Mohammed; Nimmagadda, Subbaiah Chary; Al-Matary, Yahya S.; Fiori, Maren; May, Tobias; Frank, Daria; Patnana, Pradeep Kumar; Récher, Christian; Schliemann, Christoph; Mikesch, Jan-Henrik; Koenig, Thorsten; Rosenbauer, Frank; Hartmann, Wolfgang; Tuckermann, Jan; Dührsen, Ulrich; Lanying, Wei; Dugas, Martin; Opalka, Bertram; Lenz, Georg; Khandanpour, Cyrus
Dexamethasone-mediated inhibition of Notch signalling blocks the interaction of leukaemia and mesenchymal stromal cells.
British journal of haematology, 196 :995-1006
February 2022
187.
[eng] Nilsson, Karin H.; Wu, Jianyao; Gustafsson, Karin L.; El Shahawy, Maha; Koskela, Antti; Tuukkanen, Juha; Tuckermann, Jan; Henning, Petra; Lerner, Ulf H.; Ohlsson, Claes; Movérare-Skrtic, Sofia
Estradiol and RSPO3 regulate vertebral trabecular bone mass independent of each other.
American journal of physiology. Endocrinology and metabolism, 322 :E211-E218
March 2022
186.
[eng] Stifel, Ulrich; Wolfschmitt, Eva-Maria; Vogt, Josef; Wachter, Ulrich; Vettorazzi, Sabine; Tews, Daniel; Hogg, Melanie; Zink, Fabian; Koll, Nora Maria; Winning, Sandra; Mounier, Rémi; Chazaud, Bénédicte; Radermacher, Peter; Fischer-Posovszky, Pamela; Caratti, Giorgio; Tuckermann, Jan
Glucocorticoids coordinate macrophage metabolism through the regulation of the tricarboxylic acid cycle.
Molecular metabolism, 57 :101424
March 2022
185.
[eng] Nandi, Sayantan; Chennappan, Saravanakkumar; Andrasch, Yannik; Fidan, Miray; Engler, Melanie; Ahmad, Mubashir; Tuckermann, Jan P.; Zenker, Martin; Cirstea, Ion Cristian
Increased osteoclastogenesis contributes to bone loss in the Costello syndrome Hras G12V mouse model.
Frontiers in cell and developmental biology, 10 :1000575
2022
184.
[eng] Vettorazzi, Sabine; Haffner-Luntzer, Melanie; Lee, Sooyeon; Dorn, Ann-Kristin; Ignatius, Anita; Tuckermann, Jan; Ahmad, Mubashir
Inhibition of Cdk5 Ameliorates Skeletal Bone Loss in Glucocorticoid-Treated Mice.
Biomedicines, 10
February 2022
183.
[eng] Ahmad, Mubashir; Kroll, Torsten; Vettorazzi, Sabine; Dorn, Ann-Kristin; Mengele, Florian; Lee, Sooyeon; Nandi, Sayantan; Yilmaz, Dilay; Stolz, Miriam; Tangudu, Naveen Kumar; Vázquez, David Carro; Pachmayr, Johanna; Cirstea, Ion Cristian; Spasic, Maja Vujic; Ploubidou, Aspasia; Ignatius, Anita; Tuckermann, Jan
Inhibition of Cdk5 increases osteoblast differentiation and bone mass and improves fracture healing.
Bone research, 10 :33
April 2022
182.
[eng] Meyer Zu Reckendorf, Sofia; Moser, Diana; Blechschmidt, Anna; Joga, Venkata Neeha; Sinske, Daniela; Hegler, Jutta; Deininger, Stefanie; Catanese, Alberto; Vettorazzi, Sabine; Antoniadis, Gregor; Boeckers, Tobias; Knöll, Bernd
Motoneuron-Specific PTEN Deletion in Mice Induces Neuronal Hypertrophy and Also Regeneration after Facial Nerve Injury.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 42 :2474-2491
March 2022
181.
[eng] Stifel, Ulrich; Caratti, Giorgio; Tuckermann, Jan
Novel insights into the regulation of cellular catabolic metabolism in macrophages through nuclear receptors.
FEBS letters, 596 :2617-2629
October 2022
180.
[eng] Schoppa, Astrid M.; Chen, Xiangxu; Ramge, Jan-Moritz; Vikman, Anna; Fischer, Verena; Haffner-Luntzer, Melanie; Riegger, Jana; Tuckermann, Jan; Scharffetter-Kochanek, Karin; Ignatius, Anita
Osteoblast lineage Sod2 deficiency leads to an osteoporosis-like phenotype in mice.
Disease models & mechanisms, 15
May 2022
179.
[eng] Caratti, Bozhena; Fidan, Miray; Caratti, Giorgio; Breitenecker, Kristina; Engler, Melanie; Kazemitash, Naser; Traut, Rebecca; Wittig, Rainer; Casanova, Emilio; Ahmadian, Mohammad Reza; Tuckermann, Jan P.; Moll, Herwig P.; Cirstea, Ion Cristian
The glucocorticoid receptor associates with RAS complexes to inhibit cell proliferation and tumor growth.
Science signaling, 15 :eabm4452
March 2022
178.
[eng] Maity-Kumar, Gandhari; Ständer, Lisa; DeAngelis, Meri; Lee, Sooyeon; Molenaar, Anna; Becker, Lore; Garrett, Lillian; Amerie, Oana V.; Hoelter, Sabine M.; Wurst, Wolfgang; Fuchs, Helmut; Feuchtinger, Annette; Gailus-Durner, Valerie; García-Cáceres, Cristina; Othman, Ahmed E.; Brockmann, Caroline; Schöffling, Vanessa I.; Beiser, Katja; Krude, Heiko; Mroz, Piotr A.; Hofmann, Susanna; Tuckermann, Jan; DiMarchi, Richard D.; Angelis, Martin; Tschöp, Matthias H.; Pfluger, Paul T.; Müller, Timo D.
Validation of Mct8/Oatp1c1 dKO mice as a model organism for the Allan-Herndon-Dudley Syndrome.
Molecular metabolism, 66 :101616
December 2022
177.
[eng] Bülow, Jasmin; Tuckermann, Jan; Ignatius, Anita; Haffner-Luntzer, Melanie
Correction: Steppe et al. Bone Mass and Osteoblast Activity Are Sex-Dependent in Mice Lacking the Estrogen Receptor α in Chondrocytes and Osteoblast Progenitor Cells. Int. J. Mol. Sci. 2022, 23, 2902.
May 2022
176.
[eng] Kroon, Jan; Schilperoort, Maaike; In Het Panhuis, Wietse; Berg, Rosa; Doeselaar, Lotte; Verzijl, Cristy R. C.; Trigt, Nikki; Mol, Isabel M.; Sips, Hetty H. C. M.; Heuvel, Jose K.; Koorneef, Lisa L.; Sluis, Ronald J.; Fenzl, Anna; Kiefer, Florian W.; Vettorazzi, Sabine; Tuckermann, Jan P.; Biermasz, Nienke R.; Meijer, Onno C.; Rensen, Patrick C. N.; Kooijman, Sander
A physiological glucocorticoid rhythm is an important regulator of brown adipose tissue function.
Molecular metabolism, 47 :101179
May 2021
175.
[eng] Barnea-Zohar, Maayan; Winograd-Katz, Sabina E.; Shalev, Moran; Arman, Esther; Reuven, Nina; Roth, Lee; Golani, Ofra; Stein, Merle; Thalji, Fadi; Kanaan, Moien; Tuckermann, Jan; Geiger, Benjamin; Elson, Ari
An SNX10-dependent mechanism downregulates fusion between mature osteoclasts.
Journal of cell science, 134
May 2021
174.
[eng] Nairz, Manfred; Metzendorf, Christoph; Vujic-Spasic, Maja; Mitterstiller, Anna-Maria; Schroll, Andrea; Haschka, David; Hoffmann, Alexander; Von Raffay, Laura; Sparla, Richard; Huck, Christian W.; Talasz, Heribert; Moser, Patrizia L.; Muckenthaler, Martina U.; Weiss, Günter
Cell-specific expression of Hfe determines the outcome of Salmonella enterica serovar Typhimurium infection in mice.
Haematologica, 106 :3149-3161
December 2021
173.
[eng] Pfänder, Pauline; Eiers, Ann-Kathrin; Burret, Ute; Vettorazzi, Sabine
Deletion of Cdk5 in Macrophages Ameliorates Anti-Inflammatory Response during Endotoxemia through Induction of C-Maf and Il-10.
International journal of molecular sciences, 22
September 2021
172.
[eng] Lee, Sooyeon; Ignatius, Anita; Tuckermann, Jan
Distinct Glucocorticoid Receptor Actions in Bone Homeostasis and Bone Diseases.
Frontiers in endocrinology, 12 :815386
2021
171.
[eng] Tschaffon, Miriam Eva Angelica; Fischer, Verena; Tuckermann, Jan; Ignatius, Anita; Haffner-Luntzer, Melanie
Estrogen Receptor α Signaling in Osteoblasts is Required for Mechanotransduction in Bone Fracture Healing.
Frontiers in bioengineering and biotechnology, 9 :782355
2021
170.
[eng] Giroud, Maude; Tsokanos, Foivos-Filippos; Caratti, Giorgio; Kotschi, Stefan; Khani, Sajjad; Jouffe, Céline; Vogl, Elena S.; Irmler, Martin; Glantschnig, Christina; Gil-Lozano, Manuel; Hass, Daniela; Khan, Asrar Ali; Garcia, Marcos Rios; Mattijssen, Frits; Maida, Adriano; Tews, Daniel; Fischer-Posovszky, Pamela; Feuchtinger, Annette; Virtanen, Kirsi A.; Beckers, Johannes; Wabitsch, Martin; Uhlenhaut, Henriette; Blüher, Matthias; Tuckermann, Jan; Scheideler, Marcel; Bartelt, Alexander; Herzig, Stephan
HAND2 is a novel obesity-linked adipogenic transcription factor regulated by glucocorticoid signalling.
Diabetologia, 64 :1850-1865
August 2021