Publications

You find here a complete list of publications authored or coauthered by members of our institute since 1974. By default the entire list is presented.

2022

983.
Biczo, A.; Bereczki, F.; Koch, K.; Varga, P. P.; Genodisc, Consortium; Lazary, A.
Genetic variants of interleukin 1B and 6 are associated with clinical outcome of surgically treated lumbar degenerative disc disease
BMC Musculoskelet Disord, 23 (1) :774
2022
DOI:10.1186/s12891-022-05711-0
File:https://www.ncbi.nlm.nih.gov/pubmed/35964023
982.
Palanca, Marco; Liebsch, Christian; Hübner, Shamila; Marras, Daniele; Ruspi, Maria Luisa; Marconi, Francesco; Cristofolini, Luca; Wilke, Hans-Joachim
Global and local characterization explains the different mechanisms of failure of the human ribs
J Mech Behav Biomed Mater, 125 :104931
2022
DOI:https://doi.org/10.1016/j.jmbbm.2021.104931
File:https://www.sciencedirect.com/science/article/pii/S1751616121005622
981.
Nguyen, A. Q.; Harada, G. K.; Leverich, K. L.; Khanna, K.; Louie, P. K.; Basques, B. A.; Tao, Y.; Galbusera, F.; Niemeyer, F.; Wilke, H. J.; An, H. S.; Samartzis, D.
High-Intensity Zones on MRI of the Cervical Spine in Patients: Epidemiology and Association With Pain and Disability
Global Spine J, 12 (5) :829-839
2022
DOI:10.1177/2192568220966328
980.
Wade, K.; Berger-Roscher, N.; Saggese, T.; Rasche, V.; Wilke, H.J.
How annulus defects can act as initiation sites for herniation
Eur Spine J, 31 (6) :1487-1500
2022
DOI:10.1007/s00586-022-07132-y
File:https://www.ncbi.nlm.nih.gov/pubmed/35174401
979.
Liebsch, Christian; Wilke, Hans-Joachim
How Does the Rib Cage Affect the Biomechanical Properties of the Thoracic Spine? A Systematic Literature Review
Front Bioeng Biotechnol, 10 :904539
2022
DOI:10.3389/fbioe.2022.904539
978.
Kirsch, Valeria; Ramge, Jan-Moritz; Schoppa, Astrid; Ignatius, Anita; Riegger, Jana
In Vitro Characterization of Doxorubicin-Mediated Stress-Induced Premature Senescence in Human Chondrocytes
Cells, 11 (7) :1106
2022
DOI:10.3390/cells11071106
977.
Haffner-Luntzer, Melanie; Lee, Sooyeon; Dorn, Ann-Kristin; Ignatius, Anita; Tuckermann, Jan; Ahmad, Mubashir
Inhibition of Cdk5 Ameliorates Skeletal Bone Loss in Glucocorticoid-Treated Mice
Biomedicines, 10 (2) :404
2022
DOI:10.3390/biomedicines10020404
File:https://www.mdpi.com/2227-9059/10/2/404
976.
Dorn, A. K.; Stolz, M.; Tangudu, N. K.; Vazquez, D. C.; Pachmayr, J.; Spasic, M. V.
Inhibition of Cdk5 increases osteoblast differentiation and bone mass and improves fracture healing
Bone Res, 10 (1) :33
2022
DOI:10.1038/s41413-022-00195-z
File:https://www.ncbi.nlm.nih.gov/pubmed/35383146
975.
Fischer, V.
Interaction between bone and immune cells: Implications for postmenopausal osteoporosis
Semin Cell Dev Biol, 123 :14-21
2022
DOI:10.1016/j.semcdb.2021.05.014
File:https://www.ncbi.nlm.nih.gov/pubmed/34024716
974.
Goncalves, Raquel M.; Saggese, Taryn; Yong, Zhiyao; Ferreira, Joana R.; Ignatius, Anita; Wilke, Hans-Joachim; Neidlinger-Wilke, Cornelia; Teixeira, Graciosa Q.
Interleukin-1β More Than Mechanical Loading Induces a Degenerative Phenotype in Human Annulus Fibrosus Cells, Partially Impaired by Anti-Proteolytic Activity of Mesenchymal Stem Cell Secretome
Front Bioeng Biotechnol, 9 :802789
2022
DOI:10.3389/fbioe.2021.802789
973.
Haussner, F.; Maitz, A.; Rasche, V.; Hoffmann, A.; Braumuller, S.; Lupu, L.; Neff, T. A.; Palmer, A.
Intestinal damage and immune response after experimental blunt abdominal trauma
Shock, 58 (4) :332-340
2022
DOI:10.1097/SHK.0000000000001986
File:https://www.ncbi.nlm.nih.gov/pubmed/36018298
972.
Seitz, A. M.; Schwer, J.; Roy, L.; Warnecke, D.; Dürselen, L.
Knee Joint Menisci Are Shock Absorbers: A Biomechanical In-Vitro Study on Porcine Stifle Joints
Front Bioeng Biotechnol, 10 :837554
2022
DOI:10.3389/fbioe.2022.837554
File:https://www.ncbi.nlm.nih.gov/pubmed/35372324
971.

Knochenheilung bei Osteoporose: Pathomechanismen und innovative Therapiekonzepte
Spitzenforschung Orthopädie und Unfallchirurgie :18-24
2022
970.
Ragipoglu, D.; Bülow, J.; Hauff, K.; Voss, M.; Fischer, V.
Mast Cells Drive Systemic Inflammation and Compromised Bone Repair After Trauma
Front Immunol, 13 :883707
2022
DOI:10.3389/fimmu.2022.883707
File:https://www.ncbi.nlm.nih.gov/pubmed/35558068
969.
Fischer, V.; Ragipoglu, D.; Diedrich, J.; Steppe, L.; Schutze, K.; Kalbitz, M.; Gebhard, F.
Mast Cells Trigger Disturbed Bone Healing in Osteoporotic Mice
J Bone Miner Res, 37 (1) :137-151
2022
DOI:10.1002/jbmr.4455
File:https://www.ncbi.nlm.nih.gov/pubmed/34633111
968.
Schlager, Benedikt; Krump, Florian; Boettinger, Julius; Jonas, René; Liebsch, Christian; Ruf, Michael; Beer, Meinrad; Wilke, Hans‐Joachim
Morphological patterns of the rib cage and lung in the healthy and adolescent idiopathic scoliosis
J Anat, 240 (1) :120-130
2022
DOI:10.1111/joa.13528
967.
Kuhn, M. R.; Kempter, E.; Reber, S. O.; Ichinose, H.; Vacher, J.; Tschaffon-Muller, M. E. A.
Myeloid cell-derived catecholamines influence bone turnover and regeneration in mice
Front Endocrinol (Lausanne), 13 :997745
2022
DOI:10.3389/fendo.2022.997745
File:https://www.ncbi.nlm.nih.gov/pubmed/36187089
966.
Cui, Shangbin; Li, Wenyue; Teixeira, Graciosa Q.; Neidlinger‐Wilke, Cornelia; Wilke, Hans‐Joachim; Haglund, Lisbet; Ouyang, Hongwei; Richards, R. Geoff; Grad, Sibylle; Alini, Mauro; Li, Zhen
Neoepitope fragments as biomarkers for different phenotypes of intervertebral disc degeneration
Jor Spine, 5 (5) :e1215
2022
DOI:10.1002/jsp2.1215
965.
Schoppa, A. M.; Chen, X.; Ramge, J. M.; Vikman, A.; Fischer, V.; Riegger, J.; Scharffetter-Kochanek, K.
Osteoblast lineage Sod2 deficiency leads to an osteoporosis-like phenotype in mice
Dis Model Mech, 15 (5) :dmm049392
2022
DOI:10.1242/dmm.049392
File:https://www.ncbi.nlm.nih.gov/pubmed/35394023
964.
Garcia-Moreno, Marina; Jordan, Paul M.; Günther, Kerstin; Dau, Therese; Fritzsch, Christian; Vermes, Monika; Schoppa, Astrid; Ignatius, Anita; Wildemann, Britt; Werz, Oliver; Löffler, Bettina; Tuchscherr, Lorena
Osteocytes Serve as a Reservoir for Intracellular Persisting Staphylococcus aureus Due to the Lack of Defense Mechanisms
Front Microbiol, 13 :Article 937466
2022
DOI:10.3389/fmicb.2022.937466
963.
Schütz, U.; Martensen, T.; Kleiner, S.; Dreyhaupt, J.; Wegener, M.; Wilke, H. J.; Beer, M.
T2*-Mapping of Knee Cartilage in Response to Mechanical Loading in Alpine Skiing: A Feasibility Study
Diagnostics (Basel), 12 (6) :1391
2022
DOI:10.3390/diagnostics12061391
File:https://www.ncbi.nlm.nih.gov/pubmed/35741201
962.
Ruf, M.; Pitzen, T.; Nennstiel, I.; Volkheimer, D.; Drumm, J.; Puschel, K.; Wilke, H. J.
The effect of posterior compression of the facet joints for initial stability and sagittal profile in the treatment of thoracolumbar fractures: a biomechanical study
Eur Spine J, 31 (1) :28-36
2022
DOI:10.1007/s00586-021-07034-5
File:https://www.ncbi.nlm.nih.gov/pubmed/34773149
961.
Baker, J. D.; Sayari, A. J.; Harada, G. K.; Tao, Y.; Louie, P. K.; Basques, B. A.; Galbusera, F.; Niemeyer, F.; Wilke, H. J.; An, H. S.; Samartzis, D.
The Modic-Endplate-Complex Phenotype in Cervical Spine Patients: Association with Symptoms and Outcomes
J Orthop Res, 40 (2) :449-459
2022
DOI:10.1002/jor.25042
File:https://www.ncbi.nlm.nih.gov/pubmed/33749924
960.
Liebsch, C.; Tao, Y.; Kienle, A.; Wilke, H. J.
Validity and interobserver agreement of a new radiographic grading system for intervertebral disc degeneration: Part III. Thoracic spine
Eur Spine J, 31 (3) :726-734
2022
DOI:10.1007/s00586-021-06970-6
File:https://www.ncbi.nlm.nih.gov/pubmed/34460004
959.
Liebsch, C.; Wilke, H.J.
Which traumatic spinal injury creates which degree of instability? A systematic quantitative review
Spine J, 22 (1) :136-156
2022
DOI:https://doi.org/10.1016/j.spinee.2021.06.004
958.
Sehring, I.; Mohammadi, H. F.
Zebrafish fin regeneration involves generic and regeneration-specific osteoblast injury responses
Elife, 11 :e77614
2022
DOI:10.7554/eLife.77614
File:https://www.ncbi.nlm.nih.gov/pubmed/35748539

2021

957.
Schwarz, F.; Liebsch, C.; Berger-Roscher, N.; Wilke, H. J.; Sakr, Y.; Kalff, R.; Waschke, A.
A biomechanical comparison of a cement-augmented odontoid screw with a posterior-instrumented fusion in geriatric patients with an odontoid fracture type IIb
Eur Spine J, 30 (6) :1566–1573
2021
DOI:10.1007/s00586-021-06848-7
File:https://www.ncbi.nlm.nih.gov/pubmed/33929612
956.
Lee, Naomi N.; Salzer, Elias; Bach, Frances C.; Bonilla, Andres F.; Cook, James L.; Gazit, Zulma; Grad, Sibylle; Ito, Keita; Smith, Lachlan J.; Vernengo, Andrea; Wilke, Hans-Joachim; Engiles, Julie B.; Tryfonidou, Marianna A.
A comprehensive tool box for large animal studies of intervertebral disc degeneration
JOR Spine, 4 (2) :e1162
2021
DOI:https://doi.org/10.1002/jsp2.1162
File:https://onlinelibrary.wiley.com/doi/abs/10.1002/jsp2.1162
955.
Niemeyer, F.; Galbusera, F.; Tao, Y.; Kienle, A.; Beer, M.; Wilke, H. J.
A Deep Learning Model for the Accurate and Reliable Classification of Disc Degeneration Based on MRI Data
Invest Radiol, 56 (2) :78-85
2021
DOI:10.1097/rli.0000000000000709
954.
Schild, L. R.; Bohm, F.; Boos, M.; Kahrs, L. A.; Coburger, J.; Greve, J.; Dürselen, L.; Hoffmann, T. K.; Schuler, P. J.
Adding Flexible Instrumentation to a Curved Videolaryngoscope: A Novel Tool for Laryngeal Surgery
Laryngoscope, 131 (2) :E561-E568
2021
DOI:10.1002/lary.28868
File:https://www.ncbi.nlm.nih.gov/pubmed/32585046
953.
Freitag, T.; Bieger, R.; Kiefer, H.; Dornacher, D.; Reichel, H.; Dürselen, L.
Biomechanics of a calcar loading and a shortened tapered femoral stem: Comparative in-vitro testing of primary stability and strain distribution
J Exp Orthop, 8 (1) :74
2021
DOI:10.1186/s40634-021-00388-1
File:https://www.ncbi.nlm.nih.gov/pubmed/34491456
952.
Freitag, T.; Kutzner, K. P.; Bieger, R.; Reichel, H.; Dürselen, L.
Biomechanics of a cemented short stem: a comparative in vitro study regarding primary stability and maximum fracture load
Arch Orthop Trauma Surg, 141 (10) :1797-1806
2021
DOI:10.1007/s00402-021-03843-x
File:https://www.ncbi.nlm.nih.gov/pubmed/33755800
951.
Klatte-Schulz, F.; Bormann, N.; Voss, I.; Melzer, J.; Schmock, A.; Bucher, C.; Thiele, K.; Moroder, P.; Duda, G.; Wildemann, B.
Bursa-derived cells show a distinct mechano-response to physiological and pathological loading in vitro
Front Cell Dev Biol, 9 :657166
2021
DOI:doi: 10.3389/fcell.2021.657166
950.
Riesner, H. J.; Blattert, T. R.; Krezdorn, R.; Schadler, S.; Wilke, H. J.
Can cavity-based pedicle screw augmentation decrease screw loosening? A biomechanical in vitro study
Eur Spine J, 30 (8) :2283–2291
2021
DOI:10.1007/s00586-020-06676-1
File:https://www.ncbi.nlm.nih.gov/pubmed/33355707
949.
Vasilikos, I.; Teixeira, G. Q.; Seitz, A.; Nothelfer, J.; Haas, J.; Wilke, H. J.; Mizaikoff, B.; Beck, J.; Hubbe, U.; Neidlinger-Wilke, C.
Can UVA-light-activated riboflavin-induced collagen crosslinking be transferred from ophthalmology to spine surgery? A feasibility study on bovine intervertebral disc
PLoS One, 16 (6) :e0252672
2021
DOI:10.1371/journal.pone.0252672
File:https://www.ncbi.nlm.nih.gov/pubmed/34081754
948.
Harada, G. K.; Tao, Y.; Louie, P. K.; Basques, B. A.; Galbusera, F.; Niemeyer, F.; Wilke, H. J.; Goldberg, E.; An, H. S.; Samartzis, D.
Cervical Spine MRI Phenotypes and Prediction of Pain, Disability and Adjacent Segment Degeneration/Disease after ACDF
J Orthop Res, 39 (3) :657-670
2021
DOI:10.1002/jor.24658
File:https://www.ncbi.nlm.nih.gov/pubmed/32159238
947.
Huber-Lang, M. S.; Kohl, J.; Mannes, M.; Braun, C. K.
Complement in Trauma - Traumatised Complement?
Br J Pharmacol, 178 (14) :2863-2879
2021
DOI:10.1111/bph.15245
File:https://www.ncbi.nlm.nih.gov/pubmed/32880897
946.
Haffner-Luntzer, Melanie; Fischer, Verena; Ignatius, Anita
Differences in Fracture Healing Between Female and Male C57BL/6J Mice
Front Physiol, 12 :1227
2021
DOI:10.3389/fphys.2021.712494
File:https://www.frontiersin.org/article/10.3389/fphys.2021.712494
945.
Treuheim, T.; Zengerle, L.; Hecht, A. C.; Wilke, H. J.; Iatridis, J. C.
Does the neutral zone quantification method matter? Efficacy of evaluating neutral zone during destabilization and restabilization in human spine implant testing
J Biomech, 129 :110756
2021
DOI:https://doi.org/10.1016/j.jbiomech.2021.110756
File:https://www.sciencedirect.com/science/article/pii/S0021929021005224
944.
Ehnert, Sabrina; Relja, Borna; Schmidt-Bleek, K.; Fischer, Verena; Ignatius, Anita; Linnemann, Caren; Rinderknecht, Helen; Huber-Lang, Markus; Kalbitz, Miriam; Histing, Tina; Nüssler, Andreas
Effects of immune cells on mesenchymal stem cells during fracture healing
World J Stem Cells, 13 (11) :1667-1695
2021
DOI:DOI: 10.4252/wjsc.v13.i11.1667
943.
Steppe, L.; Krüger, Benjamin T.; Fischer, V.
Estrogen receptor α signaling in osteoblasts is required for mechanotransduction in bone fracture healin
Front Bioeng Biotechnol
2021
942.
Schild, L. R.; Boehm, F.; Kienle, L.; Seitz, A.; Kahrs, L. A.; Boeckers, T. M.; Greve, J.; Hoffmann, T. K.; Schuler, P. J.
Evaluation of a curved surgical prototype in a human larynx
Eur Arch Otorhinolaryngol, 278 :2927–2935
2021
DOI:10.1007/s00405-021-06791-9
File:https://doi.org/10.1007/s00405-021-06791-9
941.
Haffner-Luntzer, Melanie
Experimental agents to improve fracture healing: utilizing the WNT signaling pathway
Injury, 52 :S44-S48
2021
DOI:10.1016/j.injury.2020.11.051
File:http://www.sciencedirect.com/science/article/pii/S0020138320309773
940.
Liebsch, C.; Hübner, C.; Palanca, M.; Cristofolini, L.; Wilke, H.J.
Experimental study exploring the factors that promote rib fragility in the elderly
Sci Rep, 11 :9307
2021
DOI:https://doi.org/10.1038/s41598-021-88800-9
File:pdfhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC8085244/pdf/41598_2021_Article_88800.pdf
939.
Seitz, A.; Schall, F.; Drongelen, S.; Wolf, S.; Dürselen, L.
Forces at the anterior meniscal attachments strongly increase under dynamic knee joint loading
Am J Sports Med, 49 (4) :994-1004
2021
DOI:10.1177/0363546520988039
938.
Zengerle, L.; Fleege, C.; Treuheim, T.; Vogele, D.; Rauschmann, M.; Wilke, H. J.
Georg Schmorl Prize of the German Spine Society (DWG) 2020: new biomechanical in vitro test method to determine subsidence risk of vertebral body replacements
Eur Spine J, 30 (5) :1117-1124
2021
DOI:10.1007/s00586-021-06764-w
File:https://www.ncbi.nlm.nih.gov/pubmed/33730216
937.
Claes, Lutz
Improvement of clinical fracture healing-what can be learned from mechano-biological research?
J Biomech, 115 :110148
2021
DOI:10.1016/j.jbiomech.2020.110148
File:http://www.sciencedirect.com/science/article/pii/S0021929020305728
936.
Zengerle, Laura; Debout, Elisabeth; Kluger, Bruno; Zöllner, Lena; Wilke, Hans-Joachim
In Vitro Model for Lumbar Disc Herniation to Investigate Regenerative Tissue Repair Approaches
Applied Sciences, 11 (6)
2021
DOI:10.3390/app11062847
935.
Luntzer, Kathrin; Lackner, Ina; Weber, Birte; Mödinger, Yvonne; Ignatius, Anita; Gebhard, Florian; Mihaljevic, Susann-Yvonne; Haffner-Luntzer, Melanie; Kalbitz, Miriam
Increased Presence of Complement Factors and Mast Cells in Alveolar Bone and Tooth Resorption
Int J Mol Sci, 22 (5) :2759
2021
DOI:10.3390/ijms22052759
934.
Sukopp, Matthias; Schall, Florian; Hacker, Steffen P.; Ignatius, Anita; Dürselen, Lutz; Seitz, Andreas Martin
Influence of menisci on tibiofemoral contact mechanics in human knees: A systematic review
Front Bioeng Biotechnol
2021
933.
Hachemi, Yasmine; Rapp, Anna E.; Lee, Sooyeon; Dorn, Ann-Kristin; Krüger, Benjamin T.; Kaiser, Kathrin; Ignatius, Anita; Tuckermann, Jan
Intact Glucocorticoid Receptor Dimerization Is Deleterious in Trauma-Induced Impaired Fracture Healing
Front Immunol, 11 (3913) :628287
2021
DOI:10.3389/fimmu.2020.628287
File:https://www.frontiersin.org/article/10.3389/fimmu.2020.628287
932.
Mallow, G. M.; Siyaji, Z. K.; Galbusera, F.; Espinoza-Orias, A. A.; Giers, M.; Lundberg, H.; Ames, C.; Karppinen, J.; Louie, P. K.; Phillips, F. M.; Pourzal, R.; Schwab, J.; Sciubba, D. M.; Wang, J. C.; Wilke, H. J.; Williams, F. M. K.; Mohiuddin, S. A.; Makhni, M. C.; Shepard, N. A.; An, H. S.; Samartzis, D.
Intelligence-Based Spine Care Model: A New Era of Research and Clinical Decision-Making
Global Spine J, 11 (2) :135-145
2021
DOI:10.1177/2192568220973984
File:https://www.ncbi.nlm.nih.gov/pubmed/33251858
931.
Teixeira, G. Q.; Yong, Z.; Kuhn, A.; Riegger, J.; Goncalves, R. M.; Ruf, M.; Mauer, U. M.; Brenner, R. E.; Neidlinger-Wilke, C.
Interleukin-1β and cathepsin D modulate formation of the terminal complement complex in cultured human disc tissue
Eur Spine J (8) :2247-2256
2021
DOI:https://doi.org/10.1007/s00586-021-06901-5
930.
Galbusera, F.; Niemeyer, F.; Tao, Y.; Cina, A.; Sconfienza, L. M.; Kienle, A.; Wilke, H. J.
ISSLS Prize in Bioengineering Science 2021: in vivo sagittal motion of the lumbar spine in low back pain patients-a radiological big data study
Eur Spine J, 30 (5) :1108-1116
2021
DOI:10.1007/s00586-021-06729-z
File:https://www.ncbi.nlm.nih.gov/pubmed/33475843
929.
La Barbera, L.; Wilke, H. J.; Ruspi, M. L.; Palanca, M.; Liebsch, C.; Luca, A.; Brayda-Bruno, M.; Galbusera, F.; Cristofolini, L.
Load-sharing biomechanics of lumbar fixation and fusion with pedicle subtraction osteotomy
Sci Rep, 11 (1) :3595
2021
DOI:10.1038/s41598-021-83251-8
File:https://www.ncbi.nlm.nih.gov/pubmed/33574504
928.
Fischer, V.; Ragipoglu, D.; Diedrich, J.; Steppe, L.; Schuetze, K.; Kalbitz, M.; Gebhard, F.
Mast cells trigger disturbed bone healing in osteoporotic mice
J Bone Miner Res
2021
927.
Roy, L.; Warnecke, Daniela; Simon, U.; Dürselen, Lutz; Ignatius, Anita; Seitz, Andreas M.
Meniscus injury and its surgical treatment does not increase initial whole knee joint friction
Front Bioeng Biotechnol
2021
926.
Neidlinger-Wilke, C.; Ekkerlein, A.; Goncalves, R; Ferreira, J. R.; Ignatius, A; Wilke, H.; Teixeira, G. Q.
Mesenchymal stem cell secretome decreases the inflammatory response in annulus fibrosus organ cultures
Eur Cell Mater, 42 :1-19
2021
DOI:10.22203/eCM.v042a01
925.
Wilke, Hans-Joachim; Betz, Volker Michael; Kienle, Annette
Morphometry of the kangaroo spine and its comparison with human spinal data
J Anat, 238 (3) :626-642
2021
DOI:10.1111/joa.13323
File:https://onlinelibrary.wiley.com/doi/abs/10.1111/joa.13323
924.
Seitz, Andreas Martin; Murrmann, Miriam; Ignatius, Anita; Dürselen, Lutz; Friemert, Benedikt; Lübken, Falk
Neuromapping of the Capsuloligamentous Knee Joint Structures
Arthrosc Sports Med Rehabil, 3 (2) :e555-e563
2021
DOI:10.1016/j.asmr.2020.12.009
File:pdfhttps://www.sciencedirect.com/science/article/pii/S2666061X21000031 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8129484/pdf/main.pdf
923.
Wildemann, B.; Leung, F.; Taitsman, L. A.; Smith, R. M.; Pesantez, R.; Stoddart, M. J.; Richards, R. G.; Jupiter, J. B.
Non-union bone fractures
Nat Rev Dis Primers, 7 (1) :57
2021
DOI:10.1038/s41572-021-00289-8
File:https://www.ncbi.nlm.nih.gov/pubmed/34354083
922.
Seitz, Andreas M.; Osthaus, Felix; Schwer, Jonas; Warnecke, Daniela; Faschingbauer, Martin; Sgroi, Mirco; Ignatius, Anita; Dürselen, Lutz
Osteoarthritis-Related Degeneration Alters the Biomechanical Properties of Human Menisci Before the Articular Cartilage
Front Bioeng Biotechnol, 9 :659989
2021
DOI:10.3389/fbioe.2021.659989
File:pdfhttps://www.frontiersin.org/article/10.3389/fbioe.2021.659989 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8134692/pdf/fbioe-09-659989.pdf
921.
Maity, P.; Singh, K.; Krug, L.; Koroma, A.; Hainzl, A.; Bloch, W.; Kochanek, S.; Wlaschek, M.; Geiger, H.; Scharffetter-Kochanek, K.
Persistent JunB activation in fibroblasts disrupts stem cell niche interactions enforcing skin aging
Cell Rep, 36 (9) :109634
2021
DOI:10.1016/j.celrep.2021.109634
File:https://www.ncbi.nlm.nih.gov/pubmed/34469740
920.
Hendrickx, G.; Fischer, V.; Kroge, S.; Brylka, L.; Pawlus, E.; Schweizer, M.; Yorgan, T.; Baranowsky, A.; Rolvien, T.; Schumacher, U.; Beech, D. J.
Piezo1 Inactivation in Chondrocytes Impairs Trabecular Bone Formation
J Bone Miner Res, 36 (2) :369-384
2021
DOI:10.1002/jbmr.4198
File:https://www.ncbi.nlm.nih.gov/pubmed/33180356
919.
Tao, Youping; Galbusera, Fabio; Niemeyer, Frank; Samartzis, Dino; Vogele, Daniel; Wilke, Hans-Joachim
Radiographic cervical spine degenerative findings: a study on a large population from age 18 to 97 years
Eur Spine J, 30 (2) :431 - 443
2021
DOI:10.1007/s00586-020-06615-0
File:https://doi.org/10.1007/s00586-020-06615-0
918.
Chakraborty, S.; Winkelmann, V. E.; Braumuller, S.; Palmer, A.; Schultze, A.; Klohs, B.; Vater, A.; Fauler, M.; Frick, M.
Role of the C5a-C5a receptor axis in the inflammatory responses of the lungs after experimental polytrauma and hemorrhagic shock
Sci Rep, 11 (1) :2158
2021
DOI:10.1038/s41598-020-79607-1
File:https://www.ncbi.nlm.nih.gov/pubmed/33495506
917.
Tao, Y.; Niemeyer, F.; Galbusera, F.; Jonas, R.; Samartzis, D.; Vogele, D.; Kienle, A.; Wilke, H. J.
Sagittal wedging of intervertebral discs and vertebral bodies in the cervical spine and their associations with age, sex and cervical lordosis: a large-scale morphological study
Clin Anat, 34 (7) :1111–1120
2021
DOI:10.1002/ca.23769
916.
Engelhardt, L.; Niemeyer, F.; Christen, P.; Müller, R.; Stock, K.; Blauth, M.; Urban, K.; Simon, U.
Simulating Metaphyseal Fracture Healing in the Distal Radius
Biomechanics, 1 :29-42
2021
DOI:10.3390/biomechanics1010003
915.
Lackner, Ina; Weber, Birte; Haffner-Luntzer, Melanie; Hristova, Simona; Gebhard, Florian; Lam, Charles; Morioka, Kazuhito; Marcucio, Ralph S.; Miclau, Theodore; Kalbitz, Miriam
Systemic and local cardiac inflammation after experimental long bone fracture, traumatic brain injury and combined trauma in mice
J Orthop Translat, 28 :39-46
2021
DOI:10.1016/j.jot.2020.12.003
File:https://www.sciencedirect.com/science/article/pii/S2214031X20301583
914.
Maitz, A.; Haussner, F.; Braumuller, S.; Hoffmann, A.; Lupu, L.; Wachter, U.; Radermacher, P.; Braun, C. K.; Wilke, H. J.; Vogt, M.; Barth, T. F. E.; Palmer, A.
Temporal-spatial organ response after blast-induced experimental blunt abdominal trauma
FASEB J, 35 (12) :e22038
2021
DOI:10.1096/fj.202100995R
File:https://www.ncbi.nlm.nih.gov/pubmed/34748229
913.
Teixeira, Graciosa Q.; Yong, Zhiyao; Goncalves, Raquel M.; Kuhn, Amelie; Riegger, Jana; Brisby, Helena; Barreto Henriksson, Helena; Ruf, Michael; Nerlich, Andreas; Mauer, Uwe M.; Ignatius, Anita; Brenner, Rolf E.; Neidlinger-Wilke, Cornelia
Terminal complement complex formation is associated with intervertebral disc degeneration
Eur Spine J, 30 (1) :217-226
2021
DOI:10.1007/s00586-020-06592-4
File:https://doi.org/10.1007/s00586-020-06592-4
912.
Liebsch, C.; Wilke, H.
The effect of multiplanar loading on the intradiscal pressure of the whole human spine: Systematic review and meta-analysis
Eur Cell Mater, 41 :388-400
2021
911.
Tao, Youping; Galbusera, Fabio; Niemeyer, Frank; Jonas, René; Samartzis, Dino; Vogele, Daniel; Wilke, Hans-Joachim
The impact of age, sex, disc height loss and T1 slope on the upper and lower cervical lordosis: a large-scale radiologic study
Eur Spine J, 30 (9) :2434-2442
2021
DOI:10.1007/s00586-021-06933-x
File:https://doi.org/10.1007/s00586-021-06933-x
910.
Faschingbauer, M.; Seitz, A.; Dürselen, L.; Boettner, F.; Reichel, H.
The tibial cut in total knee arthroplasty influences the varus alignment, the femoral roll-back and the tibiofemoral rotation in patients with constitutional varus
Knee Surg Sports Traumatol Arthrosc, 29 (2) :641–651
2021
DOI:10.1007/s00167-020-05996-5
File:https://www.ncbi.nlm.nih.gov/pubmed/32306132

2020

909.
Weber, B.; Lam, C.; Fischer, V.; Kalbitz, M.; Marcucio, R. S.; Miclau, T.
A novel mouse model to study fracture healing of the proximal femur
J Orthop Res, 38 (10) :2131-2138
2020
DOI:10.1002/jor.24677
File:https://www.ncbi.nlm.nih.gov/pubmed/32232999
908.

Animal models to study metaphyseal bone fracture healing
Eur Cell Mater, 40 :172-188
2020
DOI:10.22203/eCM.v040a11
907.
Teixeira, J. H.; Pereira, C. L.; Almeida, M. I.; Teixeira, G. Q.; Gonalves, R. M.; Barbosa, M. A.; Santos, S. G.
Articular Repair/Regeneration in Healthy and Inflammatory Conditions: From Advanced In Vitro to In Vivo Models
Adv Funct Mater, 30 (44) :1909523
2020
DOI:10.1002/adfm.201909523
File:
906.
Rahman, Muhammed Masudur; Dürselen, Lutz; Seitz, Andreas Martin
Automatic Segmentation of Knee Menisci - A Systematic Review
Artif Intell Med (105) :101849
2020
DOI:10.1016/j.artmed.2020.101849
File:http://www.sciencedirect.com/science/article/pii/S0933365718307723
905.
Schröter, L.; Kaiser, F.; Stein, S.; Gbureck, U.
Biological and mechanical performance and degradation characteristics of calcium phosphate cements in large animals and humans
Acta Biomater, 117 :1-20
2020
DOI:10.1016/j.actbio.2020.09.031
File:https://www.ncbi.nlm.nih.gov/pubmed/32979583
904.
La Barbera, L.; Wilke, H. J.; Liebsch, C.; Villa, T.; Luca, A.; Galbusera, F.; Brayda-Bruno, M.
Biomechanical in vitro comparison between anterior column realignment and pedicle subtraction osteotomy for severe sagittal imbalance correction
Eur Spine J, 29 (1) :36-44
2020
DOI:10.1007/s00586-019-06087-x
File:https://www.ncbi.nlm.nih.gov/pubmed/31414289
903.
Harada, G. K.; Alter, K.; Nguyen, A. Q.; Tao, Y.; Louie, P. K.; Basques, B. A.; Galbusera, F.; Niemeyer, F.; Wilke, H. J.; An, H. S.; Samartzis, D.
Cervical Spine Endplate Abnormalities & Association with Pain, Disability and Adjacent Segment Degeneration after Anterior Cervical Discectomy and Fusion
Spine (Phila Pa 1976), 45 (15) :E917-E926
2020
DOI:10.1097/BRS.0000000000003460
File:https://www.ncbi.nlm.nih.gov/pubmed/32097271
902.
Sgroi, M.; Gninka, J.; Fuchs, M.; Seitz, A. M.; Reichel, H.; Kappe, T.
Chondral lesions at the medial femoral condyle, meniscal degeneration, anterior cruciate ligament insufficiency, and lateral meniscal tears impair the middle-term results after arthroscopic partial meniscectomy
Knee Surg Sports Traumatol Arthrosc, 28 (11) :3488–3496
2020
DOI:10.1007/s00167-020-05883-z
File:https://www.ncbi.nlm.nih.gov/pubmed/32036398
901.
Schwer, J.; Rahman, M.; Stumpf, K.; Rasche, V.; Dürselen, L.; Seitz, A.
Degeneration Affects Three-dimensional Strains in Human Menisci: In Situ MRI Acquisition Combined with Image Registration
Front Bioeng Biotechnol, 8 :582055
2020
DOI:10.3389/fbioe.2020.582055
900.
Warnecke, D.; Balko, J.; Bieger, R.; Leucht, F.; Wolf, N.; Schild, N.; Stein, S.; Seitz, A.; Reichel, H.; Dürselen, L.
Degeneration alters the biomechanical properties and structural composition of lateral human menisci
Osteoarthritis Cartilage, 28 (11) :1482-1491
2020
DOI:10.1016/j.joca.2020.07.004
File:https://www.ncbi.nlm.nih.gov/pubmed/32739340
899.
Ruspi, Maria Luisa; Palanca, Marco; Cristofolini, Luca; Liebsch, Christian; Villa, Tomaso; Brayda-Bruno, Marco; Galbusera, Fabio; Wilke, Hans-Joachim; La Barbera, Luigi
Digital Image Correlation (DIC) Assessment of the Non-Linear Response of the Anterior Longitudinal Ligament of the Spine during Flexion and Extension
Materials, 13 (2) :384
2020
DOI:10.3390/ma13020384
File:https://www.mdpi.com/1996-1944/13/2/384
898.
Wade, K.; Berger-Roscher, N.; Rasche, V.; Wilke, H.
Disc wall structural abnormalities can act as initiation sites for herniation
Eur Cell Mater, 40 :227-238
2020
DOI:10.22203/eCM.v040a14
File:https://www.ncbi.nlm.nih.gov/pubmed/33227141
897.
Sobacchi, C.
Editorial: Innate Immunity in the Context of Osteoimmunology
Frontiers in Immunology, 11 (603)
2020
DOI:10.3389/fimmu.2020.00603
File:https://www.frontiersin.org/article/10.3389/fimmu.2020.00603
896.
Liedert, Astrid; Nemitz, Claudia; Haffner-Luntzer, Melanie; Schick, Fabian; Jakob, Franz; Ignatius, Anita
Effects of Estrogen Receptor and Wnt Signaling Activation on Mechanically Induced Bone Formation in a Mouse Model of Postmenopausal Bone Loss
Int J Mol Sci, 21 (21) :8301
2020
DOI:10.3390/ijms21218301
File:https://www.mdpi.com/1422-0067/21/21/8301
895.
Galbusera, F.; Niemeyer, F.; Bassani, T.; Sconfienza, L. M.; Wilke, H. J.
Estimating the three-dimensional vertebral orientation from a planar radiograph: Is it feasible?
J Biomech (102) :109328
2020
DOI:10.1016/j.jbiomech.2019.109328
File:https://www.ncbi.nlm.nih.gov/pubmed/31526588
894.
Wilke, Hans-Joachim; Herkommer, A.; Werner, K.; Liebsch, C.
In vitro analysis of the intradiscal pressure of the thoracic spine
Front Bioeng Biotechnol, 8 :614
2020
DOI:10.3389/fbioe.2020.00614
893.
Wilke, H. J.; Grundler, S.; Ottardi, C.; Mathew, C. E.; Schlager, B.; Liebsch, C.
In vitro analysis of thoracic spinal motion segment flexibility during stepwise reduction of all functional structures
Eur Spine J, 29 (1) :179-185
2020
DOI:10.1007/s00586-019-06196-7
File:https://www.ncbi.nlm.nih.gov/pubmed/31664565
892.
Liebsch, C.; Aleinikov, V.; Kerimbayev, T.; Akshulakov, S.; Kocak, T.; Vogt, M.; Jansen, J. U.; Wilke, H. J.
In vitro comparison of personalized 3D printed versus standard expandable titanium vertebral body replacement implants in the mid-thoracic spine using entire rib cage specimens
Clin Biomech (Bristol, Avon), 78 :105070
2020
DOI:10.1016/j.clinbiomech.2020.105070
File:https://www.ncbi.nlm.nih.gov/pubmed/32531440
891.
Steppe, L.
Influence of low-magnitude high-frequency vibration on bone cells and bone regeneration
Front Bioeng Biotechnol, 8 :595139
2020
DOI:10.3389/fbioe.2020.595139
890.
Jonas, R.; Demmelmaier, R.; Wilke, H. J.
Influences of functional structures on the kinematic behavior of the cervical spine
Spine J, 20 (12) :2014-2024
2020
DOI:10.1016/j.spinee.2020.07.017
889.
Vasilikos, I.; Teixeira, G. Q.; Nothelfer, J.; Neidlinger-Wilke, C.; Wilke, H. J.; Seitz, A.; Vavvas, D. G.; Zentner, J.; Beck, J.; Hubbe, U.
Infrared attenuated total reflection spectroscopic surface analysis of bovine-tail intervertebral discs after UV-light-activated riboflavin-induced collagen crosslinking
J Biophotonics, 13 (10) :e202000110
2020
DOI:10.1002/jbio.202000110
File:https://www.ncbi.nlm.nih.gov/pubmed/32589779
888.
Schopper, C.; Faschingbauer, M.; Moeller, R. T.; Gebhard, F.; Dürselen, L.; Seitz, A.
Modified Candy-Package technique vs Cerclage technique for refixation of the lesser trochanteric fragment in pertrochanteric femoral fractures. A biomechanical comparison of 10 specimens
Injury, 51 (81763-1768)
2020
DOI:10.1016/j.injury.2020.06.008
File:https://www.ncbi.nlm.nih.gov/pubmed/32580889
887.
Zengerle, L.; Kohler, A.; Debout, E.; Hackenbroch, C.; Wilke, H. J.
Nucleus replacement could get a new chance with annulus closure
Eur Spine J, 29 (7) :1733-1741
2020
DOI:10.1007/s00586-020-06419-2
File:https://www.ncbi.nlm.nih.gov/pubmed/32333186
886.
Wölfle-Roos, J.; Katmer Amet, B.; Fiedler, J.; Michels, H.; Kappelt, G.; Dürselen, L.; Reichel, H.; Brenner, R.
Optimizing Manufacturing and Osseointegration of Ti6Al4V Implants through Precision Casting and Calcium and Phosphorus Ion Implantation? In Vivo Results of a Large-Scale Animal Trial
Materials, 13 (7) :1670
2020
DOI:10.3390/ma13071670
File:https://www.mdpi.com/1996-1944/13/7/1670
885.
Stein, S.; Kruck, L.; Warnecke, D.; Seitz, A.; Dürselen, L.
Osseointegration of titanium implants with a novel silver coating under dynamic loading
Eur Cell Mater, 39 :249-259
2020
DOI:10.22203/eCM.v039a16
File:https://www.ncbi.nlm.nih.gov/pubmed/32602932
884.
Winter, E. M.; Ireland, A.; Butterfield, N. C.; Horcajada, M. N.; Veldhuis-Vlug, A.; Oei, L.; Colaianni, G.; Bonnet, N.
Pregnancy and lactation, a challenge for the skeleton
Endocr Connect, 9.6 :R143-R157
2020
DOI:10.1530/EC-20-0055
File:https://www.ncbi.nlm.nih.gov/pubmed/32438342

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