| Project team at the institute | Dr Gisela Büchele, Andrea Jaensch, Dr Jochen Klenk, Torben Fischer |
PROFinD is an interdisciplinary project funded by the Federal Ministry of Education and Research (BMBF ). It aims to prevent and rehabilitate osteoporotic fractures in disadvantaged populations. In the first approved phase, 5 sub-projects with different orientations will start.
| Contribution of the Institute | Sub-project 1: Identification of target populations with disadvantages |
Subproject 1 consists of 2 work packages. On the one hand, the burden of disease of osteoporotic fractures (OF) is to be determined in people living on an outpatient basis who require care. On the other hand, the sub-project deals with the epidemiology of OF in people with intellectual disabilities.
Work package 1: OF in ambulatory peoplewith care needs
Fractures in old and very old people often result from a combination of reduced bone density and an increased tendency to fall. In order to reduce the incidence of OF, it is necessary to precisely identify the high-risk groups. In Germany, around 70% of people in need of care live at home. To date, there is no data available on how this group of people contributes to the fracture-related burden of disease.
The aim of the analyses is therefore to
- Determine the rate of OF in people living at home with and without care needs
- Influence of pre-existing diseases such as Parkinson's disease or stroke on the occurrence of OF
- Influence of previous hospital stays (associated with a change of location) on the fracture risk in people living at home with care needs
- Influence of OF in people living at home with/without care needs on their risk of institutionalisation
Pseudonymised routine data from the AOK Bavaria are used as the data basis.
Work package 2: OF in people with intellectual disability (gB)
Due to the significant increase in life expectancy among people with gB, a significant absolute increase in this group of people can be assumed. This group of people has a number of factors that predispose them to falls (e.g. neuromuscular problems, foot deformities, psychotropic medication, seizures) or reduced bone density (e.g. hypogonadism, paralyses, vitamin D deficiency, anticonvulsants). To date, however, there are hardly any epidemiological studies on the disease burden of fall-related fractures in people with gB.
The aim of the analyses is therefore:
- Determining the burden of disease of OF in people with intellectual disability The AOK is also a partner in the second "work package". However, data from Baden-Württemberg is used
| Funding period: | 08/2010-07/2013 |
Study management: | Prof Dr Clemens Becker |
| Co-operation partner: |
| Subproject | Head of Office | Institution | Title of the sub-project |
| 2 | Prof H. H. König | University Hospital Hamburg-Eppendorf (formerly Leipzig University) | Health economics of OF |
| 3 | RBMF | Design and piloting of a population- based intervention | |
| 4 | Prof N.Schott | University of Stuttgart | Prevention of loss of function after osteoporotic wrist fractures |
| 5 | Prof M. Hautzinger | University of Tübingen | Reduction of fear of falling after hip and pelvic fractures |
