M. Sc. Thomas Büchler
Interests
- Algorithms and Complexity
- Sequence Analysis: Pangenoms, Alignments, Pattern Matching
Project
Pan-Genome Structures: Desing, Construction, and Applications
Puplications
See also Orc
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Thomas Büchler. Pangenome Structures: Design, Construction, and Applications. Dissertation (Submitted)
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Jannik Olbrich; Thomas Büchler; Enno Ohlebusch. Generating Multiple Alignments on a Pangenomic Scale (Submitted to Bioinformatics 2024)
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Enno Ohlebusch; Thomas Büchler; Jannik Olbrich. Faster computation of Chinese frequent strings and their net frequencies (Accepted on SPIRE 2024)
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Thomas Büchler; Jannik Olbrich; Enno Ohlebusch. Efficient short read mapping to a pangenome that is represented by a graph of ED strings. Journal: Bioinformatics 2023, https://doi.org/10.1093/bioinformatics/btad320
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Uwe Baier; Thomas Büchler; Enno Ohlebusch; Pascal Weber. Edge Minimization in de Bruijn Graphs. Information and Computation 2022, doi.org/10.1016/j.ic.2021.104795
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Thomas Büchler; Caroline Räther, Pascal Weber; Enno Ohlebusch. Coordinate Systems for Pangenome Graphs based on the Level Function and Minimum Path Covers. Conference: BIOINFORMATICS 2021 : doi.org/10.5220/0010165400210029 (Award: Best Student Paper)
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Uwe Baier; Thomas Büchler; Enno Ohlebusch; Pascal Weber. Edge Minimization in de Bruijn Graphs. Data Compression Conference 2020, doi.org/10.1109/DCC47342.2020.00030
- Thomas Büchler; Enno Ohlebusch. An improved encoding of genetic variation in a Burrows-Wheeler transform. Journal: Bioinformatics 2019 , https://doi.org/10.1093/bioinformatics/btz782
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Technical Report: Thomas Büchler. Transforming a bidirected sequence graph into an EDS Graph, to enable the usage of the HPRC reference in the software GED-MAP. (2023)
Teaching
- Kompletxitätstheorie (Exercises) [SS-24]
- Algorithmik: Thema Optimierung (Seminar) [SS-24]
- Grundlagen der Theoretischen Informatik (Exercises) [WS-23/24]
- Algorithmen (Seminar) [SS-23]
- Algorithmen und Datenstrukturen (Exercises) [WS-22/23]
- Algorithmn Engeneering: Thema Pan-Genom-Read-Mapping (Project) [SS-22]
- Algorithmen und Datenstrukturen (Exercises) [WS-21/22]
- Berechenbarkeit und Komplexität (Exercises) [SS-21]
- Logik (Exercises) [SS-21]
Function
Scientific assistant
Consultation hours
By appointment
Contact
E-Mail
Room: O27/532
Phone: +49 (0)731 50 24108
Fax: +49 (0)731 50 1224101