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23.-25.06.2024

SFB 1074 Retreat - Grand Hotel Dino (Lago Maggiore Italy)

After 12 successful years, we all came together to celebrate the end of our SFB 1074. It was a bittersweet moment filled with updates of all the projects, meetings and scientific exchanges, meals and lots of laughter under the italian sun!

Flyer

18.04.2024

Speaker: Prof. Bernhard Gentner
Ludwig Institute for Cancer Research Lausanne
Lausanne, Switzerland

Title: Single cell analysis of normal and malignant hematopoietic stem cells

Location: Seminar Room 2609/10, Internal Medicine
Time: 16:30 - 17:30
Hosts: Prof. Lüder Meyer
Department of Pediatrics and Adolescent Medicine

Announcement

CV

Bernhard Gentner and Lüder Meyer

14.03.2024

Speaker: Prof. Paul Bourgine
Lund University, Lund, Sweden

Title: Engineering human bone Marrow niches for disease modeling

Location: Seminar Room 2609/10, Internal Medicine
Time: 16:30 - 17:30
Hosts: Prof. Hartmut Geiger
Institute for Molecular Biology

Announcement

CV

Hartmut Döhner, Paul Bourgine and Hartmut Geiger

07.03.2024

Speaker: Dr. Gabriele Casirati
Dana-Farber Institute / Boston Children's Cancer and Blood Disorder Center
Boston, MA, USA

Title: Epitope editing to enable targeted immunotherapy of Acute Myeloid Leukemia

Location: Seminar Room 2609/10, Internal Medicine
Time: 16:30 - 17:30
Hosts: Prof. Hartmut Döhner & Dr. Elisa Sala
Department of Internal Medicine III

Announcement

CV

Elisa Sala, Gabriele Casirati and Hartmut Döhner

15.02.2024

Speaker: Prof. Dr. Mascha Binder
Universitätsspital Basel

Title: The antigen receptor as targe for cellular therapies in lymphomas

Location: Seminar Room 2609/10, Internal Medicine
Time: 16:30 - 17:30
Hosts: Prof. Dr. Hassan Jumaa
Institute for Immunology

Announcement

CV

Hassan Jumaa, Mascha Binder and Hartmut Döhner

18.01.2024

Speaker: Prof. Victor Tybulewicz
The Francis Crick Institute, London, UK

Title: Critical Roles for Ion and Water Flux in B and T cell migration and activation

Location: Seminar Room 2609/10, Internal Medicine
Time: 16:30 - 17:30
Hosts: Dr. Elias Hobeika
Institute for Immunology

Announcement

CV

Hassan Jumaa, Victor Tubylewicz, Elias Hobeika

16.11.2023

Speaker: Dr. Jérome Paggetti
Luxembourg Institute of Health

Title: Chronic lymphocytic leukemia, microenvironment, and novel therapies

Location: Seminar Room 2611, Internal Medicine
Time: 16:30 - 17:30
Hosts: Dr. Billy Jebaraj and Prof. Stephan Stilgenbauer
Deparment of Internal Medicine III and Comprehensive Cancer Center Ulm

Announcement

CV

Billy Jebaraj, Jerome Paggetti, Stephan Stilgenbauer

19.10.2023

Speaker: Dr. Christian Braun
Haunersches Kinderspital, LMU München

Title: Targeting dysegulated transcription programs in cancer

Location: Seminar Room 2609/10, Internal Medicine
Time: 16:30 - 17:30
Host: Prof. Lüder Meyer, Klinik für Kinder- und Jugendmedizin

Announcement

CV

Lüder Meyer and Christian Braun

28.09.2023

Speaker: Dr. Meike Vogler
Kinderkrebsstiftung Frankfurt

Title: Targeting apoptosis signalling in pediatric cancer

Location: TTU Hörsaal
Time: 16:30 - 17:30
Host: Prof. Klaus-Michael Debatin, Klinik für Kinder- und Jugendmedizin

Announcement

CV

Meike Vogler

20.07.2023

Speaker: Dr. Megan S. Lim
Memorial Sloan Kettering Cancer Center
New York, USA

Title: Integrated genomic and proteomic approaches reveal novel biologic insights in fusion kinase-driven anaplastic large cell lymphoma

Location: Seminar Room 2609/10, Internal Medicine
Time: 16:30 - 17:30
Host: Prof. Reiner Siebert, Institute of Human Genetics

Announcement

CV

Reiner Siebert and Megan Lim

19.-20.06.2023

SFB 1074 Retreat - Hotel Bad Schachen (Lindau)

Flyer

15.06.2023

Speaker: Prof. Arndt Borkhardt
Universitätsklinikum Düsseldorf

Title: Towards prevention of childhood ALL

Location: Seminar Room 2609/10, Internal Medicine
Time: 16:30 - 17:30
Host: Prof. Klaus-Michael Debatin, Klinik für Kinder- und Jugendmedizin

Announcement

CV

Arndt Borkhardt und Klaus-Michael Debatin

11.05.2023

Speaker: PD Dr. Niklas Gebauer
Universitätsklinikum Schleswig-Holstein, Lübeck, Germany

Title: Blastic plasmacytoid dentritic cell neoplasm through the eyes of a precision oncologist - a multi-omics approach

Location: Seminar Room 2609/10, Internal Medicine
Time: 17:00 - 18:00
Host: Prof. Reiner Siebert, Institute of Human Genetics

Announcement

CV

Hanno Witte, Niklas Gebauer, Reiner Siebert and Emil Chteinberg

20.04.2023

Speaker: Vera Martins, PhD
Instituto Gulbenkian de Ciência, Oeiras, Portugal

Title: Establishing thymic cell competition following bone marrow correction of yc-deficiency is required to prevent T-cell acute lymphoblastic leukemia

Location: Seminar Room 2609/10, Internal Medicine
Time: 16:30 - 17:30
Host: Prof. Klaus-Michael Debatin, Department of Pediatrics and Adolescent Medicine

Announcement

CV

Klaus-Michael Debatin and Vera Martins

16.02.2023

Speaker: Prof. Laurence de Leval
Institut Universitaire de Pathologie, Lausanne, Switzerland

Title: Insights into the molecular pathogenesis of T-cell lymphomas

Location: Seminar Room 2622, Internal Medicine
Time: 16:30 - 17:30
Host: Prof. Reiner Siebert, Institute of Human Genetics

Announcement

CV

Eugen Tausch, Reiner Siebert, Laurence de Leval and Hartmut Döhner

26.01.2023

Speaker: Rushad Pavri, PhD
Research Institute of Molecular Pathology (IMP), Vienna, Austria

Title: DNA replication timing in the biogenesis of lymphomagenic translocations in B cells

Location: Multimedia Room 2.059, Building N27
Time: 17:00 - 18:00
Host: Prof. Hassan Jumaa and Dr. Elias Hobeika (Institute of Molecular Medicine)

Announcement

CV

Rushad Pavri, PhD

27.10.2022

Speaker: Eleni Papanikolaou, PhD
Miltenyi Biotec B.V. Co. KG, Bergisch-Gladbach
Nationaland Kapodistrian University of Athens, Greece

Title: Genetic therapies of blood diseases in the horizon

Location: Room 2609/10 (Medical Building)
Time: 17:00 - 18:00
Host: Prof. Hartmut Geiger (Institute of Molecular Medicine)

Announcement

CV

Eleni Papanikolaou, PhD

11.10.2022

Speaker: Nicoletta Cieri
Dana-Farber Cancer Institute, Boston, MA (USA)

Title: Systematic identification of minor histocompatibility antigens to address GVHD and GVL

Location: Room 2609/10 (Medical Building)
Time: 17:00 - 18:00
Host: Prof. Hartmut Döhner (Department of Internal Medicine III)

Announcement

CV

Elisa Sala, Nicoletta Cieri, Hartmut Döhner

10.10.2019

Speaker: Prof. Georg Holländer
University of Basel, Switzerland and University of Oxford, UK

Title: The rise-and-fall of the thymus: Molecular and cellular insight

Location: Room 2609/10 (Medical Building)
Time: 17:00 - 18:00
Host: Dr. Elias Hobeika & Prof. Hassan Jumaa (Institute of Immunology)

Announcement

Hassan Jumaa, Georg Holländer and Elias Hobeika

18.07.2019

Speaker: Prof. Ursula Klingmüller
German Cancer Research Center (DKFZ), Heidelberg, Germany

Title: A systems biology approach to the regulation of erythropoiesis and towards application in erythroleukemia

Location: Room 2609/10 (Medical Building)
Time: 17:00 - 18:00
Host: Prof. Michaela Feuring-Buske (Innere Medizin III)

Announcement

U. Klingmüller, M. Feuring-Buske

11.07.2019

Speaker: Prof. Ulf Klein
St. James' University Hospital, University of Leeds, UK

Title: The germinal center B-cell reaction: physiology and disruption in malignancy

Location: Room 2609/10 (Medical Building)
Time: 17:00 - 18:00
Host: Prof. Hassan Jummaa (Institute of Immunology)

Announcement

H. Jumaa and U. Klein

24.-25.06.2019

SFB 1074 Retreat - Hotel Bad Schachen (Lindau)

Flyer

04.04.2019

Mini-Symposium

Speakers:
Dr. Lorenzo Brunetti
University of Perugia, Italy

Title: New insights into the biology of acute myeloid leukemia with mutated NPM1

Dr. Stefano Indraccolo
Istituto Oncologico Veneto - IRCCS, Padova, Italy

Title: Dissecting molecular mechanisms of resistance to Notch1-targeted therapy int-cell acute lymphoblastic leukemia xenografts

Location: Room 2609/10 (Medical Building)
Time: 17:00 - 18:00
Hosts: Dr. Jan Krönke (Internal Medicine III) & Prof. Lüder Hinrich Meyer (Dept. of Pediatrics and Adolescent Medicine)

L. Brunetti, J. Krönke, L. Meyer, S. Indraccolo

21.03.2019

Speaker: Prof. Roland Schmitz
University of Duisburg-Essen

Title: Genetics of aggressive B-cell lymphoma: Implications for precision medicine

Location: Room 2609/10 (Medical Building)
Time: 17:00 - 18:00
Host: Prof. Reiner Siebert (Institute of Human Genetics)

Announcement

R. Wagener, R. Schmitz, R. Siebert

24.01.2019

Speaker: Prof. Ralf Küppers
University of Duisburg-Essen, Medical School

Title: Mechanisms of lymphoma pathogenesis

Location: Room 2609/10 (Medical Building)
Time: 16:00 - 17:00
Host: Prof. Reiner Siebert & Dr. Rabea Wagener

Announcement

Rabea Wagener, Ralf Küppers and Reiner Siebert

17.-18.01.2019

SFB 1074 Retreat - Hotel Oberstdorf

Flyer

22.11.2018

Speaker: Prof. Jude Fitzgibbon
Barts Cancer Center, London, UK

Title: Will new genetic data help cure Follicular Lymphoma?

Location: Room 2609/10 (Medical Building)
Time: 17:00 - 18:00
Host: Prof. Reiner Siebert

Announcement

Reiner Siebert and Jude Fitzgibbon

30.10.2018

Speaker: Prof. Thomas Kietzmann
University of Oulu, Finnland

Title: The hypoxia response: Old features and new aspects

Location: Room 2609/10 (Medical Building)
Time: 17:00 - 18:00
Host: Dr. Daniel Mertens and Dr. Viola Close

Announcement

Thomas Kietzmann and Viola Close

13.09.2018

Speaker: Dr. Maria de las Nieves Peltzer
UCL Cancer Institute, London, UK

Title: Physiological role of linear ubiquitination: regulation of cell death-driven inflammation beyond TNF

Location: Room 2609/10 (Medical Building)
Time: 17:00 - 18:00
Host: Prof. Dr. Klaus-Michael Debatin

Announcement

Nieves Peltzer and Klaus-Michael Debatin

27.09.18
Speaker:  Dr. Dimitar Efremov
International Center for Genetic Engineering & Biotechnology
Trieste, Italy

Title:  B cell receptor and associated pathways in CLL: implications for biology and treatment
Location:
Room 2622 (Medical Building)
Time: 17:00 - 18:00
Host:  Prof. Hassan Jumaa

Announcement

Dimitar Efremov and Hassan Jumaa

13.09.2018

Speaker:
PD Dr. rer. nat. Tanja Hartmann
Internal Medicine I amd Comprehensive Cancer Center Freiburg

Title:
Creating adhesive spots in leukemia via CD44-mediated non-conformational VLA-4 activation

Location: Multimedia Room 2.059, N27 (Experimental Research Buidling)
Time: 16:00 - 17:00
Host: PD Dr. rer. nat. Daniel Mertens

Announcement

Daniel Mertens and Tanja Hartmann

10.09.2018

SFB 1074 one-day Retreat at Klingenstein Hotel in Blaustein, Ulm

21.06.2018

Speaker:
Dr. Joan Montero Boronat
Institute for Bioengineering of Catalonia

Title:
Personalizing cancer treatment using cell-based functional assays

Location: SR 2609/10
Time: 16:00 - 17:00
Host: PD Dr. Lüder Meyer and Dr. Felix Seyfried

Announcement

06.06.2018

Speaker:
Prof. Tsvee Lapidot
The Weizmann Institute of Science, Tel Aviv, Israel

Title:
Metabolic regulation of blood and bone forming stem cells: The role of ROS, mitochondria transfer, Nitric Oxide and Melatonin

Location: Multimedia Room 2.059, N27 (Experimental Research Building)
Time: 17:00 - 18:00
Host: Prof. Hartmut Geiger

Announcement

Hartmut Döhner, Carolina Florian, Tsvee Lapidot

04.05.2018

Speaker:
Dr. Marco Herling
Universitätsklinik Köln, Germany

Title:
Are novel molecular insights already changing therapeutic approaches in T-PLL?

Location: Seminar Room 2622 (Medical Building)
Time: 10:00 - 11:00
Host: Prof. Reiner Siebert and Dr. Rabea Wagener

Announcement

Rabea Wagener, Marco Herling und Reiner Siebert

26.04.2018

Speaker:
Dr. Chris Halsey
Institute of Cancer Sciences - University of Glasgow, Scottland, UK

Title:
The continuing challenge of central nervous system infiltration in Acute Lymphoblastic Leukemina

Location: Seminar Room 2609/10 (Medical Building)
Time: 16:00 - 17:00
Host: PD Dr. Lüder Meyer

Announcement

Lüder Meyer and Chris Halsey

05.03.2018

Joint Seminar talk with CEMMA

Speaker:
Prof. Constanze Bonifer
Institute for Cancer Genomic Sciences, University of Birmingham, UK

Title:
Subtype-specific regulatory network rewiring in acute myeloid leukemia

Location: Seminar Room 2609/10 (Medical Building)
Time: 16:00 - 17:00
Host: Prof. Hartmut Geiger

Announcement

Bettina Möhrle, Constanze Bonifer and Hartmut Geiger

22.02.2018

Speaker:
Dr. Stefano Casola
IFOM, The FIRC Institute of Molecular Oncology Foundation, Milan, Italy

Title:
Targeting cancer cell fitness: lessons from MYC-driven lymphomas

Location: Seminar Room 2609/10 (Medical Building)
Time: 16:00 - 17:00
Host: Elias Hobeika

Announcement

Stefano Casola and Elias Hobeika

25. & 26.01.2018

SFB 1074 Retreat at Hotel liebes Rot-Flüh in Tannheimer Tal, Austria

01.02.2018

Speaker:
PD Dr. Ilske Oschlies
Christian-Albrechts-Universität zu Kiel
Universitätsklinikum Schleswig-Holstein, Campus Kiel


Title:
Clinical, hostomorphological and molecular characteristics of primary cutaneous B-cell lymphomas

Location: Multimedia Room 2.059, N27 (Experimental Cancer Center)
Time: 16:00 - 17:00
Hosts: Prof. Reiner Siebert and Dr. Rabea Wagener

Announcement

Reiner Siebert, Ilske Oschlies and Rabea Wagener

18.01.2018

Speaker:
Dr. Tobias Berg
Universitätsklinikum Frankfurt

Title:
LSD1 - promising target in AML

Location: Seminar Room 2609/10
Time: 16:00 - 17:00
Host: Dr. Florian Kuchenbauer

<link file:336466 download internen link im aktuellen>Announcement

Tobias Berg and Florian Kuchenbauer

16.11.2017

Speakers:
Prof. Arndt Borkhardt and Prof. Julia Hauer
Universitätsklinikum Düsseldorf

Titles:
Germline predisposition in childhood cancer - first results of a monocenter study in Düsseldorf (Prof. Borkhardt)

Can infection trigger childhood acute lymphoblastic leukemia (Prof. Hauer)

Location: Seminar Room 2609/10
Time: 16:00 - 17:30
Host: Prof. Reiner Siebert

<link file:318360 download internen link im aktuellen>Announcement

Arndt Borkhardt, Julia Hauer and Reiner Siebert

09.10.2017

Speaker:   Prof. Brian Wilhelm
Université de Montreal

Title:  Systematic studies of human models of leukemia: establishing a pipeline for novel targeted therapeutics

Location: Seminar Room 2609/10
Time: 16:00 - 17:00
Host:  Dr. Arefeh Rouhi

Announcement

Brian Wilhelm and Arefeh Rouhi
Robert Zeiser and Lars Bullinger

04.05.2017

Mini-Symposium:
Location: Hörsaal Chirurgie
Time: 16:30 - 18:00

Speakers: 
Dr. Oliver Weigert
Klinikum der Universität München
Title:  Clinical implications of gene mutation in follicular lymphoma
Host:  Prof. Stephan Stilgenbauer

Dr. José A. Cancelas Perez
University of Cincinnati College of Medicine
Title:  The signaling axis atypical protein kinase C λ/ι/Satb2 mediates leukemic transformation of B-cell precursors
Host: Hartmut Geiger

Announcement 

Stephan Stilgenbauer, Oliver Weigert, José Cancelas and Hartmut Geiger

20.04.2017

Speaker:   Dr. Sandrine Sander
dkfz Heidelberg

Title:  PI3K signaling in B cell lymphoma pathogenesis

Location:  Room 2609/10
Time:  16:00 - 17:00
Host: 
Prof. Lars Bullinger

Announcement

Lars Bullinger, Sandrine Sander and Hartmut Döhner
Sandrine Sander and Hartmut Döhner. Dr. Sander accepts this year's Franziska Kolb Prize

30.03.2017

Speaker:   Dr. med. Cyrus Khandanpour
Universitätsklinikum Essen

Title:  Function of Gfi1 in leukemia

Time:  16:00 - 17:00
Location:  Room 2609/10
Host: Prof. Konstanze Döhner

Announcement

Konstanze Döhner, Cyrus Khandanpour and Jan Krönke

08.03.2017

Speaker:   Prof. Galina Selivanova
Karolinska Institutet Stockholm
Time:  17:00 - 18:00
Location:  Room 2622
Title:  Pharmacological reactivation of p53 to treat cancer
Host:
PD Dr. Lüder Meyer

Announcement

Lüder Meyer and Galina Selivanova

16.02.2017

Speaker:   Dr. Michael Heuser
Medizinische Hochschule Hannover
Time:  16:00 - 17:00
Location:  Room 2609/10
Title:  Pathogenesis of IDH mutations in AML
Host:
Prof. Lars Bullinger

Lars Bullinger and Michael Heuser

30.01.2017

Speaker:  Ben Ebert
Harvard Medical Center
Boston, Massachussets, USA
Title:  Pathogenesis of IDH mutations in AML
Time: 16:30 - 17:30
Location: Hörsaal Chirurgie
Host: Hartmut Döhner and Jan Krönke

Announcement

Jan Krönke, Ben Ebert, Hartmut Döhner, Mridul Agrawal

26.01.2017

Speaker:  Massimo Degano
Ospedale San Raffaele
Milano, Italy
Title:  Molecular analysis of homotypic B cell receptor interactions in chronic lymphocytic leukemia
Time: 16:30 - 17:30
Location: Room 2609/10
Host:  Hassan Jumaa

Announcement

Hassan Jumaa and Massimo Degano

15.12.2016

Speaker:  Atan Gross
Weizmann Institute
Rehovot, Israel
Title:
  The ATM-BID-MTCH2 pathway regulates haematopoietic stem cell fate by controlling mitochondria metabolism
Time:
16:30 - 17:30
Location: Room 2609/10
Host:  Hans-Jörg Fehling

Announcement

Atan Gross and Hans-Jörg Fehling

24.11.2016

Speaker:  Florian Bassermann
Klinikum rechts der Isar, TUM
Munich, Germany
Title: The B cell receptor: key molecule in CLL pathogenesis and therapy
Time:  16:00 - 17:00
Location:  Experimental Research Building, Room 2.059
Host:  Jan Krönke

Jan Krönke and Florian Bassermann

18.10.2016 (Tuesday)

Speaker:   Jan Burger
MD Anderson Cancer Center

Houston, TX, USA
Title:

The B cell receptor: key molecule in CLL pathogenesis and therapy

Time:

16:00 - 17:00
Location:

Seminar Room 2609/10, Medical Building
Host:
Lüder H. Meyer and Peter Gierschik
Announcement

Jan Burger, Peter Gierschik and Lüder Meyer

29.09.2016

Speaker:   Frank Rosenbauer
Westfälische Wilhelms-Universität Münster
Title:

Epigenetic control of lineage decisions in hematopoiesis and leukemia
Time:
16:00 - 17:00
Location:
Experimental Research Building N27, Room 2.059
Host:

Lars Bullinger
Announcement

Frank Rosenbauer und Lars Bullinger

27.07.2016 (Wednesday)

Speaker: Christian Reinhardt
Uniklinik Köln
Köln, Germany
Title:  Mapping synergistic drug interactions onto the cancer genome
Time:  16:00 - 17:00
Location:  SR 2609/10 (Medical Building - N23)
Host:  Stephan Stilgenbauer
Announcement

Christian Reinhardt

21.07.2016 (Thursday)

Speaker:  Philipp Jost
Klinikum rechts der Isar, Technische Universität München
Munich, Germany
Title:  Inflammatory cell death in AML: unexpected implications for leukemia survival and blast cell differentiation
Time:  16:00 - 17:00
Location:  SR 2609/10 (Medical Building - N23)
Host:  Hartmut Döhner
Announcement

Philipp Jost

02.06.2016

Speaker:   Christian Montag
Ulm University
Ulm, Germany
Title:  Molecular genetics in psychological sciences: personality and beyond
Time:  17:00 - 18:00
Location:  SR 2609/10 (Medical Building - N23)
Host:  Lars Bullinger
Announcement

Lars Bullinger and Christian Montag