Zusammenstellung von Bildern aus dem Sonderforschungsbereich

CRC related publications

2017

114.
D. Peterlik, S. Foertsch, A. M. Fuchsl, P. Brokmann, P. J. Flor, Z. Shen, J. G. Fox, N. Uschold-Schmidt, C. A. Lowry and S. O. Reber, "Individual differences in stress vulnerability: The role of gut pathobionts in stress-induced colitis", Brain Behav Immun, vol. 64, pp. 23-32, 2017.
DOI:10.1016/j.bbi.2016.12.019
File:https://www.ncbi.nlm.nih.gov/pubmed/28012830
113.
M. C. Sportelli, E. Tutuncu, R. A. Picca, M. Valentini, A. Valentini, C. Kranz, B. Mizaikoff, H. Barth and N. Cioffi, "Inhibiting P. fluorescens biofilms with fluoropolymer-embedded silver nanoparticles: an in-situ spectroscopic study", Sci Rep, vol. 7, no. 1, pp. 11870, 2017.
DOI:10.1038/s41598-017-12088-x
File:https://www.ncbi.nlm.nih.gov/pubmed/28928400
112.
A. Magadum, Y. Ding, L. He, T. Kim, M. D. Vasudevarao, Q. Long, N. Wickramasinghe, H. V. Renikunta, N. Dubois, Q. Yang and F. B. Engel, "Live cell screening platform identifies PPARdelta as a regulator of cardiomyocyte proliferation and cardiac repair", Cell Res, vol. 27, no. 8, pp. 1002-1019, 2017.
DOI:10.1038/cr.2017.84
File:https://www.ncbi.nlm.nih.gov/pubmed/28621328
111.
C. X. Zhang, "Loss of menin in osteoblast lineage affects osteocyte-osteoclast crosstalk causing osteoporosis", Cell Death Differ, vol. 24, no. 4, pp. 672-682, 2017.
DOI:10.1038/cdd.2016.165
File:https://www.ncbi.nlm.nih.gov/pubmed/28106886
110.
J. Kroner and J. Kotrba, "Mast cells are critical regulators of bone fracture-induced inflammation and osteoclast formation and activity", J Bone Miner Res, vol. 32, no. 12, pp. 2431–2444, 2017.
DOI:10.1002/jbmr.3234
File:https://www.ncbi.nlm.nih.gov/pubmed/28777474
109.
Y. Husecken, S. Muche, M. Kustermann, M. Klingspor, A. Palmer, S. Braumuller and K. M. Debatin, "MDSCs are induced after experimental blunt chest trauma and subsequently alter antigen-specific T cell responses", Sci Rep, vol. 7, no. 1, pp. 12808, 2017.
DOI:10.1038/s41598-017-13019-6
File:https://www.ncbi.nlm.nih.gov/pubmed/28993671
108.
N. Hagemeyer, K. M. Hanft, M. A. Akriditou, N. Unger, E. S. Park, E. R. Stanley, O. Staszewski, L. Dimou and M. Prinz, "Microglia contribute to normal myelinogenesis and to oligodendrocyte progenitor maintenance during adulthood", Acta Neuropathol, vol. 134, no. 3, pp. 441-458, 2017.
DOI:10.1007/s00401-017-1747-1
File:https://www.ncbi.nlm.nih.gov/pubmed/28685323
107.
T. Itkin, A. Kumari, E. Schneider, S. Gur-Cohen, C. Ludwig, O. Kollet, K. Golan, E. Khatib-Massalha, C. M. Russo, J. D. Chisholm, A. Rouhi, H. Geiger, E. Hornstein, W. G. Kerr, F. Kuchenbauer and T. Lapidot, "MicroRNA-155 promotes G-CSF-induced mobilization of murine hematopoietic stem and progenitor cells via propagation of CXCL12 signaling", Leukemia, vol. 31, no. 5, pp. 1247-1250, 2017.
DOI:10.1038/leu.2017.50
File:https://www.ncbi.nlm.nih.gov/pubmed/28174416
106.
P. Radermacher and B. Nussbaum, "Non-Hemodynamic Effects of Catecholamines", Shock, vol. 48, no. 4, pp. 390-400, 2017.
DOI:10.1097/SHK.0000000000000879
File:https://www.ncbi.nlm.nih.gov/pubmed/28915214
105.
F. Seichter, P. Radermacher and B. Mizaikoff, "Nonlinear calibration transfer based on hierarchical Bayesian models and Lagrange Multipliers: Error bounds of estimates via Monte Carlo - Markov Chain sampling", Anal Chim Acta, vol. 951, pp. 32-45, 2017.
DOI:10.1016/j.aca.2016.11.025
File:https://www.ncbi.nlm.nih.gov/pubmed/27998484
104.
S. Bergdolt and Y. Hagele, "Osteoblast-specific overexpression of complement receptor C5aR1 impairs fracture healing", PLoS One, vol. 12, no. 6, pp. e0179512, 2017.
DOI:10.1371/journal.pone.0179512
File:https://www.ncbi.nlm.nih.gov/pubmed/28614388
103.
N. Guidi, M. Sacma, L. Standker, K. Soller, G. Marka, K. Eiwen, J. M. Weiss, F. Kirchhoff, T. Weil, J. A. Cancelas, M. C. Florian and H. Geiger, "Osteopontin attenuates aging-associated phenotypes of hematopoietic stem cells", EMBO J, vol. 36, no. 10, pp. 1463, 2017.
DOI:10.15252/embj.201796968
File:https://www.ncbi.nlm.nih.gov/pubmed/28507084
102.
M. Kalbitz, F. Gebhard, C. Thiemermann and P. Radermacher, "Oxygen in the Heart: How Much is too Much?", Shock, vol. 47, no. 4, pp. 531-532, 2017.
DOI:10.1097/SHK.0000000000000760
File:https://www.ncbi.nlm.nih.gov/pubmed/27749760
101.
F. Seichter, P. Radermacher and B. Mizaikoff, "Response-surface fits and calibration transfer for the correction of the oxygen effect in the quantification of carbon dioxide via FTIR spectroscopy", Anal Chim Acta, vol. 972, pp. 16-27, 2017.
DOI:10.1016/j.aca.2017.03.053
File:https://www.ncbi.nlm.nih.gov/pubmed/28495092
100.
S. Häfner, K. Wagner, S. Weber, B. Jung, M. Georgieff, M. Frick, P. Radermacher and F. Wagner, "Role of the Purinergic Receptor P2XR4 After Blunt Chest Trauma in Cigarette Smoke-Exposed Mice", Shock, vol. 47, no. 2, pp. 193-199, 2017.
DOI:10.1097/SHK.0000000000000726
File:https://www.ncbi.nlm.nih.gov/pubmed/27559703
99.
A. Zimprich, G. Mroz, C. Meyer Zu Reckendorf, S. Anastasiadou, P. Forstner, L. Garrett, S. M. Holter, L. Becker, C. Prehn, W. Wurst, T. Klopstock, M. Klingenspor, J. Adamski, R. Bekeredjian, M. H. Angelis and B. Knöll, "Serum Response Factor (SRF) Ablation Interferes with Acute Stress-Associated Immediate and Long-Term Coping Mechanisms", Mol Neurobiol, vol. 54, no. 10, pp. 8242-8262, 2017.
DOI:10.1007/s12035-016-0300-x
File:https://www.ncbi.nlm.nih.gov/pubmed/27914009
98.
J. Gačanin, A. Kovtun, S. Fischer, V. Schwager, J. Quambusch, S. L. Kuan, W. Liu, F. Boldt, C. Li, Z. Yang, D. Liu, Y. Wu, T. Weil, H. Barth and A. Ignatius, "Spatiotemporally Controlled Release of Rho-Inhibiting C3 Toxin from a Protein–DNA Hybrid Hydrogel for Targeted Inhibition of Osteoclast Formation and Activity", Adv Healthc Mater, vol. 6, no. 21, pp. 1700392, 2017.
DOI:10.1002/adhm.201700392
File:http://dx.doi.org/10.1002/adhm.201700392
97.
S. Foertsch, A. M. Fuchsl, S. D. Faller, H. Holzer, J. Messmann and S. O. Reber, "Splenic glucocorticoid resistance following psychosocial stress requires physical injury", Sci Rep, vol. 7, no. 1, pp. 15730, 2017.
DOI:10.1038/s41598-017-15897-2
File:https://www.ncbi.nlm.nih.gov/pubmed/29146967
96.
P. Losing, C. E. Niturad, M. Harrer, C. M. Z. Reckendorf, T. Schatz, D. Sinske, H. Lerche, S. Maljevic and B. Knöll, "SRF modulates seizure occurrence, activity induced gene transcription and hippocampal circuit reorganization in the mouse pilocarpine epilepsy model", Mol Brain, vol. 10, no. 1, pp. 30, 2017.
DOI:10.1186/s13041-017-0310-2
File:https://www.ncbi.nlm.nih.gov/pubmed/28716058
95.
C. J. Scholz and D. Fraccarollo, "The glucocorticoid receptor in monocyte-derived macrophages is critical for cardiac infarct repair and remodeling", FASEB J, vol. 31, no. 11, pp. 5122-5132, 2017.
DOI:10.1096/fj.201700317R
File:https://www.ncbi.nlm.nih.gov/pubmed/28768721
94.
M. Haffner-Luntzer, V. Fischer, K. Prystaz and A. Ignatius, "The inflammatory phase of fracture healing is influenced by oestrogen status in mice", Eur J Med Res, vol. 33, no. 1, pp. 23, 2017.
DOI:10.1186/s40001‐017‐0264‐y
93.
S. Häfner, B. Jung, B. Nubaum, F. Wagner, S. Weber, M. Georgieff, C. Szabo, R. Wang, P. Radermacher and K. Wagner, "The Role of Cystathionine-gamma-Lyase In Blunt Chest Trauma in Cigarette Smoke Exposed Mice", Shock, vol. 47, no. 4, pp. 491-499, 2017.
DOI:10.1097/SHK.0000000000000746
File:https://www.ncbi.nlm.nih.gov/pubmed/27685807
92.
E. Bonfanti, P. Gelosa, M. Fumagalli, L. Dimou, F. Vigano, E. Tremoli, M. Cimino, L. Sironi and M. P. Abbracchio, "The role of oligodendrocyte precursor cells expressing the GPR17 receptor in brain remodeling after stroke", Cell Death Dis, vol. 8, no. 6, pp. e2871, 2017.
DOI:10.1038/cddis.2017.256
File:https://www.ncbi.nlm.nih.gov/pubmed/28594400
91.
M. Kalbitz, J. Pressmar, J. Stecher, B. Weber, M. Weiss, S. Schwarz, E. Miltner and F. Gebhard, "The Role of Troponin in Blunt Cardiac Injury After Multiple Trauma in Humans", World J Surg, vol. 41, no. 1, pp. 162-169, 2017.
DOI:10.1007/s00268-016-3650-7
File:https://www.ncbi.nlm.nih.gov/pubmed/27501709
90.
M. Lattke, S. N. Reichel, A. Magnutzki, A. Abaei, V. Rasche, D. P. Calado, B. Ferger and T. Wirth, "Transient IKK2 activation in astrocytes initiates selective non-cell-autonomous neurodegeneration", Mol Neurodegener, vol. 12, no. 1, pp. 16, 2017.
DOI:10.1186/s13024-017-0157-0
File:https://www.ncbi.nlm.nih.gov/pubmed/28193238
89.
D. Wehner, T. M. Tsarouchas, A. Michael, C. Haase, M. M. Reimer, T. Becker and C. G. Becker, "Wnt signaling controls pro-regenerative Collagen XII in functional spinal cord regeneration in zebrafish", Nat Commun, vol. 8, no. 1, pp. 126, 2017.
DOI:10.1038/s41467-017-00143-0
File:https://www.ncbi.nlm.nih.gov/pubmed/28743881
88.
S. Pfaender, A. K. Sauer, S. Hagmeyer, K. Mangus, L. Linta, S. Liebau, J. Bockmann, G. Huguet, T. Bourgeron, T. M. Boeckers and A. M. Grabrucker, "Zinc deficiency and low enterocyte zinc transporter expression in human patients with autism related mutations in SHANK3", Sci Rep, vol. 7, pp. 45190, 2017.
DOI:10.1038/srep45190
File:https://www.ncbi.nlm.nih.gov/pubmed/28345660

2016

87.
W. Masselink, N. J. Cole, F. Fenyes, S. Berger, C. Sonntag, A. Wood, P. D. Nguyen, N. Cohen, F. Knopf, T. E. Hall and P. D. Currie, "A somitic contribution to the apical ectodermal ridge is essential for fin formation", Nature, vol. 535, no. 7613, pp. 542-6, 2016.
DOI:10.1038/nature18953
File:https://www.ncbi.nlm.nih.gov/pubmed/27437584
86.
S. L. Kuan, C. Förtsch, D. Y. Ng, S. Fischer, Y. Tokura, W. Liu, Y. Wu, K. Koynov, H. Barth and T. Weil, "A Supramolecular Approach toward Bioinspired PAMAM-Dendronized Fusion Toxins", Macromol Biosci, vol. 16, no. 6, pp. 803-10, 2016.
DOI:10.1002/mabi.201500417
File:https://www.ncbi.nlm.nih.gov/pubmed/26833574
85.
A. Heilmann, A. E. Rapp and R. Roessler, "Antagonizing Midkine Accelerates Fracture Healing in Mice by Enhanced Bone Formation in the Fracture Callus", Br J Pharmacol, vol. 173, no. 14, pp. 2237-49, 2016.
DOI:10.1111/bph.13503
File:http://www.ncbi.nlm.nih.gov/pubmed/27111560
84.
T. Stenzel, C. Weidgang, K. Wagner, F. Wagner, S. Weber, U. Wachter, S. Denk, M. Georgieff and P. Radermacher, "Association of Kidney Tissue Barrier Disrupture and Renal Dysfunction in Resuscitated Murine Septic Shock", Shock, vol. 46, no. 4, pp. 398-404, 2016.
DOI:10.1097/SHK.0000000000000599
File:https://www.ncbi.nlm.nih.gov/pubmed/26926005
83.
Y. Li, L. Chang, Y. Song, X. Gao, F. Roselli, W. Zhou, Y. Fang, W. Ling, H. Li, O. F. Almeida and Y. Wu, "Astrocytic GluN2A and GluN2B Oppose the Synaptotoxic Effects of Amyloid-beta1-40 in Hippocampal Cells", J Alzheimers Dis, vol. 54, no. 1, pp. 135-48, 2016.
DOI:10.3233/JAD-160297
File:https://www.ncbi.nlm.nih.gov/pubmed/27497478
82.
M. Gey, R. Wanner, C. Schilling, M. T. Pedro, D. Sinske and B. Knöll, "Atf3 mutant mice show reduced axon regeneration and impaired regeneration-associated gene induction after peripheral nerve injury", Open Biol, vol. 6, no. 8, 2016.
DOI:10.1098/rsob.160091
File:https://www.ncbi.nlm.nih.gov/pubmed/27581653
81.
C. Ehrnthaller, A. E. Rapp and F. Gebhard, "C5aR inhibition in the early inflammatory phase does not affect bone regeneration in a model of uneventful fracture healing", Eur J Med Res, vol. 21, no. 1, pp. 42, 2016.
DOI:10.1186/s40001-016-0236-7
File:https://www.ncbi.nlm.nih.gov/pubmed/27784330
80.
M. J. Harder, M. Anliker, B. Hochsmann, T. Simmet, H. Schrezenmeier, D. Ricklin, J. D. Lambris, P. N. Barlow and C. Q. Schmidt, "Comparative Analysis of Novel Complement-Targeted Inhibitors, MiniFH, and the Natural Regulators Factor H and Factor H-like Protein 1 Reveal Functional Determinants of Complement Regulation", J Immunol, vol. 196, no. 2, pp. 866-76, 2016.
DOI:10.4049/jimmunol.1501919
File:https://www.ncbi.nlm.nih.gov/pubmed/26643478
79.
M. Kalbitz, F. Fattahi, T. J. Herron, J. J. Grailer, L. Jajou, H. Lu, F. S. Zetoune, J. V. Sarma, S. M. Day, M. W. Russell, J. Jalife and P. A. Ward, "Complement Destabilizes Cardiomyocyte Function In Vivo after Polymicrobial Sepsis and In Vitro", J Immunol, vol. 197, no. 6, pp. 2353-61, 2016.
DOI:10.4049/jimmunol.1600091
File:https://www.ncbi.nlm.nih.gov/pubmed/27521340
78.
F. Gebhard, C. Q. Schmidt, A. Palmer, S. Denk and R. Wiegner, "Complement therapeutic strategies in trauma, hemorrhagic shock and systemic inflammation - closing Pandora's box?", Semin Immunol, vol. 28, no. 3, pp. 278-84, 2016.
DOI:10.1016/j.smim.2016.04.005
File:https://www.ncbi.nlm.nih.gov/pubmed/27157701
77.
M. Kalbitz, F. Fattahi, J. J. Grailer, L. Jajou, E. A. Malan, F. S. Zetoune, M. W. Russell and P. A. Ward, "Complement-induced activation of the cardiac NLRP3 inflammasome in sepsis", FASEB J, vol. 30, no. 12, pp. 3997-4006, 2016.
DOI:10.1096/fj.201600728R
File:https://www.ncbi.nlm.nih.gov/pubmed/27543123
76.
R. Sroka, J. Van Lint, S. F. Katz and M. R. Schneider, "Cortactin is a scaffolding platform for the E-cadherin adhesion complex and is regulated by protein kinase D1 phosphorylation", J Cell Sci, vol. 129, no. 12, pp. 2416-29, 2016.
DOI:10.1242/jcs.184721
File:https://www.ncbi.nlm.nih.gov/pubmed/27179075
75.
S. Schneider, A. Gruart, S. Grade, S. Kroger, F. Kirchhoff, G. Eichele, J. M. Delgado Garcia and L. Dimou, "Decrease in newly generated oligodendrocytes leads to motor dysfunctions and changed myelin structures that can be rescued by transplanted cells", Glia, vol. 64, no. 12, pp. 2201-2218, 2016.
DOI:10.1002/glia.23055
File:https://www.ncbi.nlm.nih.gov/pubmed/27615452
74.
"Dicer ablation in osteoblasts by Runx2 driven cre-loxP recombination affects bone integrity, but not glucocorticoid-induced suppression of bone formation", Sci Rep, vol. 6, pp. 32112, 2016.
DOI:10.1038/srep32112
File:https://www.ncbi.nlm.nih.gov/pubmed/27554624
73.
S. Peter, M. M. Ten Brinke, J. Stedehouder, C. M. Reinelt, B. Wu, K. Zhou, H. J. Boele, S. A. Kushner, M. G. Lee, M. J. Schmeisser, T. M. Boeckers, M. Schonewille, F. E. Hoebeek and C. I. De Zeeuw, "Dysfunctional cerebellar Purkinje cells contribute to autism-like behaviour in Shank2-deficient mice", Nat Commun, vol. 7, pp. 12627, 2016.
DOI:10.1038/ncomms12627
File:https://www.ncbi.nlm.nih.gov/pubmed/27581745
72.
E. Knoller, T. Stenzel, F. Broeskamp, R. Hornung, U. Wachter, J. A. Vogt, J. Matallo, H. Gassler, M. Matejovic, L. Lampl, M. Georgieff, P. Radermacher and S. Häfner, "Effects of Hyperoxia and Mild Therapeutic Hypothermia During Resuscitation From Porcine Hemorrhagic Shock", Crit Care Med, vol. 44, no. 5, pp. e264-77, 2016.
DOI:10.1097/CCM.0000000000001412
File:https://www.ncbi.nlm.nih.gov/pubmed/26588829
71.
A. E. Rapp, R. Bindl, S. Recknagel, A. Erbacher, I. Muller, H. Schrezenmeier, C. Ehrnthaller and F. Gebhard, "Fracture Healing Is Delayed in Immunodeficient NOD/scidIL2Rgammacnull Mice", PLoS One, vol. 11, no. 2, pp. e0147465, 2016.
DOI:10.1371/journal.pone.0147465
File:http://www.ncbi.nlm.nih.gov/pubmed/26849055
70.
F. Vigano, S. Schneider, M. Cimino, E. Bonfanti, P. Gelosa, L. Sironi, M. P. Abbracchio and L. Dimou, "GPR17 expressing NG2-Glia: Oligodendrocyte progenitors serving as a reserve pool after injury", Glia, vol. 64, no. 2, pp. 287-99, 2016.
DOI:10.1002/glia.22929
File:https://www.ncbi.nlm.nih.gov/pubmed/26464068
69.
S. O. Reber, P. H. Siebler, N. C. Donner, J. T. Morton, D. G. Smith, J. M. Kopelman, K. R. Lowe, K. J. Wheeler, J. H. Fox, J. Hassell, B. N. Greenwood, C. Jansch, A. Lechner, N. Uschold-Schmidt, A. M. Fuchsl, F. R. Walker, M. W. Hale, G. Lopez Perez, W. Van Treuren, A. Gonzalez, A. L. Halweg-Edwards, M. Fleshner, C. L. Raison, G. A. Rook, S. D. Peddada, R. Knight and C. A. Lowry, "Immunization with a heat-killed preparation of the environmental bacterium Mycobacterium vaccae promotes stress resilience in mice", Proc Natl Acad Sci U S A, vol. 113, no. 22, pp. E3130-9, 2016.
DOI:10.1073/pnas.1600324113
File:https://www.ncbi.nlm.nih.gov/pubmed/27185913
68.
D. Peterlik, S. O. Reber, A. Lechner and D. N. Mannel, "Induction of Suppressor Cells and Increased Tumor Growth following Chronic Psychosocial Stress in Male Mice", PLoS One, vol. 11, no. 7, pp. e0159059, 2016.
DOI:10.1371/journal.pone.0159059
File:https://www.ncbi.nlm.nih.gov/pubmed/27391954
67.
V. Heidler, K. Prystaz and A. E. Rapp, "Inhibition of Midkine Augments Osteoporotic Fracture Healing", PLoS One, vol. 11, no. 7, pp. e0159278, 2016.
DOI:10.1371/journal.pone.0159278
File:http://www.ncbi.nlm.nih.gov/pubmed/27410432
66.
"Molecular Actions of Glucocorticoids in Cartilage and Bone During Health, Disease, and Steroid Therapy", Physiol Rev, vol. 96, no. 2, pp. 409-47, 2016.
DOI:10.1152/physrev.00011.2015
File:https://www.ncbi.nlm.nih.gov/pubmed/26842265
65.
C. Wille and C. Koehler, "Protein Kinase D2 Assembles a Multiprotein Complex at the Trans-Golgi Network to Regulate Matrix Metalloproteinase Secretion", J Biol Chem, vol. 291, no. 1, pp. 462-77, 2016.
DOI:10.1074/jbc.M115.673582
File:https://www.ncbi.nlm.nih.gov/pubmed/26507660