Zusammenstellung von Bildern aus dem Sonderforschungsbereich

CRC related publications

2019

214.
A. Guillon, S. Preau, J. Aboab, E. Azabou, B. Jung, S. Silva, J. Textoris, F. Uhel, D. Vodovar, L. Zafrani, N. Prost, P. Radermacher and S. French Intensive Care, "Preclinical septic shock research: why we need an animal ICU", Ann Intensive Care, vol. 9, no. 1, pp. 66, 2019.
DOI:10.1186/s13613-019-0543-6
File:https://www.ncbi.nlm.nih.gov/pubmed/31183570 https://hal.archives-ouvertes.fr/hal-02153561/document
213.
A. E. Rapp, A. Vikman, Z. Ren, V. Fischer, S. Bergdolt, W. C. Song, J. D. Lambris, C. Neidlinger-Wilke and R. Brenner, "Reduced Terminal Complement Complex Formation in Mice Manifests in Low Bone Mass and Impaired Fracture Healing", Am J Pathol, vol. 189, no. 1, pp. 147-161, 2019.
DOI:10.1016/j.ajpath.2018.09.011
File:https://www.ncbi.nlm.nih.gov/pubmed/30339839
212.
L. Wrba, J. J. Ohmann, P. Eisele, S. Chakraborty, S. Braumuller, C. K. Braun, B. Klohs, A. Schultze, H. Baum and A. Palmer, "Remote Intestinal Injury Early After Experimental Polytrauma and Hemorrhagic Shock", Shock, vol. 52, no. 4, pp. e45-e51, 2019.
DOI:10.1097/SHK.0000000000001271
File:https://www.ncbi.nlm.nih.gov/pubmed/30289852
211.
A. Catanese, F. Olde Heuvel, M. Mulaw, M. Demestre, J. Higelin, G. Barbi, A. Freischmidt, J. H. Weishaupt, A. C. Ludolph, F. Roselli and T. M. Boeckers, "Retinoic acid worsens ATG10-dependent autophagy impairment in TBK1-mutant hiPSC-derived motoneurons through SQSTM1/p62 accumulation", Autophagy, vol. 15, no. 10, pp. 1719-1737, 2019.
DOI:10.1080/15548627.2019.1589257
File:pdfhttps://www.ncbi.nlm.nih.gov/pubmed/30939964 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6735587/pdf/kaup-15-10-1589257.pdf
210.
S. Foertsch, B. Weber, A. M. Fuchsl, E. Wirkert, S. Peters, G. Fois, J. Pressmar, J. M. Fegert, M. Frick, H. Gundel, M. Kalbitz and S. O. Reber, "Sensory contact to the stressor prevents recovery from structural and functional heart damage following psychosocial trauma", Brain Behav Immun, vol. 80, pp. 667-677, 2019.
DOI:10.1016/j.bbi.2019.05.013
File:https://www.ncbi.nlm.nih.gov/pubmed/31085218
209.
C. Schilling, T. Mack, S. Lickfett, S. Sieste, F. S. Ruggeri, T. Sneideris, A. Dutta, T. Bereau, R. Naraghi, D. Sinske, T. P. J. Knowles, C. V. Synatschke, T. Weil and B. Knöll, "Sequence-Optimized Peptide Nanofibers as Growth Stimulators for Regeneration of Peripheral Neurons", Advanced Functional Materials, vol. 29, no. 24, pp. 1809112, 2019.
DOI:https://doi.org/10.1002/adfm.201809112
File:
208.
H. Honkoop, D. E. Bakker, A. Aharonov, F. Kruse, A. Shakked, P. D. Nguyen, C. Heus, L. Garric, M. J. Muraro, A. Shoffner, F. Tessadori, J. C. Peterson, W. Noort, A. Bertozzi, G. Posthuma, D. Grun, W. J. Laarse, J. Klumperman, R. T. Jaspers, K. D. Poss, A. Oudenaarden, E. Tzahor and J. Bakkers, "Single-cell analysis uncovers that metabolic reprogramming by ErbB2 signaling is essential for cardiomyocyte proliferation in the regenerating heart", Elife, vol. 8, 2019.
DOI:10.7554/eLife.50163
File:pdfhttps://www.ncbi.nlm.nih.gov/pubmed/31868166 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7000220/pdf/elife-50163.pdf
207.
F. Olde Heuvel, S. Holl, A. Chandrasekar, Z. Li, R. Rehman, P. Forstner, D. Sinske, A. Palmer, D. Wiesner, A. Ludolph, B. Relja, T. Wirth, T. Boeckers, B. Knöll and F. Roselli, "STAT6 mediates the effect of ethanol on neuroinflammatory response in TBI", Brain Behav Immun, vol. 81, pp. 228-246, 2019.
DOI:10.1016/j.bbi.2019.06.019
File:https://www.ncbi.nlm.nih.gov/pubmed/31207335
206.
A. J. Heck, T. Ostertag, L. Schnell, S. Fischer, B. K. Agrawalla, P. Winterwerber, E. Wirsching, M. Fauler, M. Frick, S. L. Kuan, T. Weil and H. Barth, "Supramolecular Toxin Complexes for Targeted Pharmacological Modulation of Polymorphonuclear Leukocyte Functions", Adv Healthc Mater, vol. 8, no. 17, pp. e1900665, 2019.
DOI:10.1002/adhm.201900665
File:https://www.ncbi.nlm.nih.gov/pubmed/31318180 https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/adhm.201900665?download=true
205.
E. Karasu, B. Nilsson, J. Kohl and J. D. Lambris, "Targeting Complement Pathways in Polytrauma- and Sepsis-Induced Multiple-Organ Dysfunction", Front Immunol, vol. 10, pp. 543, 2019.
DOI:10.3389/fimmu.2019.00543
File:pdfhttps://www.ncbi.nlm.nih.gov/pubmed/30949180 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6437067/pdf/fimmu-10-00543.pdf
204.
U. Wachter, B. Lukaschewski, S. Häfner, M. Georgieff, N. Nagahara, C. Szabo and P. Radermacher, "The Effects of Genetic 3-Mercaptopyruvate Sulfurtransferase Deficiency in Murine Traumatic-Hemorrhagic Shock", Shock, vol. 51, no. 4, pp. 472-478, 2019.
DOI:10.1097/SHK.0000000000001165
File:pdfhttps://www.ncbi.nlm.nih.gov/pubmed/29668565 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6192867/pdf/nihms959306.pdf
203.
U. Wachter, B. Lukaschewski, G. Rumm, M. Georgieff, R. Torregrossa, M. Whiteman and P. Radermacher, "The Mitochondria-Targeted H2S-Donor AP39 in a Murine Model of Combined Hemorrhagic Shock and Blunt Chest Trauma", Shock, vol. 52, no. 2, pp. 230-239, 2019.
DOI:10.1097/SHK.0000000000001210
File:https://www.ncbi.nlm.nih.gov/pubmed/29927788
202.
R. Wanner, A. Abaei, V. Rasche and B. Knöll, "Three-Dimensional In vivo Magnetic Resonance Imaging (MRI) of Mouse Facial Nerve Regeneration", Front Neurol, vol. 10, pp. 310, 2019.
DOI:10.3389/fneur.2019.00310
File:pdfhttps://www.ncbi.nlm.nih.gov/pubmed/31001195 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6454117/pdf/fneur-10-00310.pdf
201.
B. Weber, M. R. Mendler, J. Pressmar, S. Hofler, C. K. Braun, H. Hummler, S. Schwarz and M. Kalbitz, "Tissue damage in the heart after cardiac arrest induced by asphyxia and hemorrhage in newborn pigs", Pediatr Res, vol. 86, no. 6, pp. 709-718, 2019.
DOI:10.1038/s41390-019-0505-6
File:https://www.ncbi.nlm.nih.gov/pubmed/31336381
200.
F. Roselli, "TREM1-ors shake the brain and gut after stroke", Nat Immunol, vol. 20, no. 8, pp. 950-952, 2019.
DOI:10.1038/s41590-019-0443-9
File:pdfhttps://www.ncbi.nlm.nih.gov/pubmed/31285627 https://www.nature.com/articles/s41590-019-0443-9.pdf

2018

199.
"[Mutual influence of immune system and bones]", Z Rheumatol, vol. 77, no. Suppl 1, pp. 8-11, 2018.
DOI:10.1007/s00393-018-0454-1
File:pdfhttps://www.ncbi.nlm.nih.gov/pubmed/29675686 https://link.springer.com/content/pdf/10.1007/s00393-018-0454-1.pdf
198.
V. Clemens, P. L. Plener, E. Brahler, R. C. Brown and J. M. Fegert, "Association of child maltreatment subtypes and long-term physical health in a German representative sample", Eur J Psychotraumatol, vol. 9, no. 1, pp. 1510278, 2018.
DOI:10.1080/20008198.2018.1510278
File:https://www.ncbi.nlm.nih.gov/pubmed/30220980
197.
R. C. Brown, P. L. Plener, E. Braehler and J. M. Fegert, "Associations of adverse childhood experiences and bullying on physical pain in the general population of Germany", J Pain Res, vol. 11, pp. 3099-3108, 2018.
DOI:10.2147/JPR.S169135
File:https://www.ncbi.nlm.nih.gov/pubmed/30584352
196.
J. Gačanin, J. Hedrich, S. Sieste, G. Glasser, I. Lieberwirth, C. Schilling, S. Fischer, H. Barth, B. Knöll, C. V. Synatschke and T. Weil, "Autonomous Ultrafast Self-Healing Hydrogels by pH-Responsive Functional Nanofiber Gelators as Cell Matrices", Adv Mater, vol. In Press, no. 2, pp. e1805044, 2018.
DOI:10.1002/adma.201805044
File:https://www.ncbi.nlm.nih.gov/pubmed/30411838
195.
K. N. Ekdahl, R. Wiegner, K. Fromell and B. Nilsson, "Auxiliary activation of the complement system and its importance for the pathophysiology of clinical conditions", Semin Immunopathol, vol. 40, no. 1, pp. 87-102, 2018.
DOI:10.1007/s00281-017-0646-9
File:https://www.ncbi.nlm.nih.gov/pubmed/28900700
194.
J. Demiselle and P. Radermacher, "Before the ICU: does emergency room hyperoxia affect outcome?", Crit Care, vol. 22, no. 1, pp. 59, 2018.
DOI:10.1186/s13054-018-1980-6
File:https://www.ncbi.nlm.nih.gov/pubmed/29519235
193.
S. L. Kuan, S. Fischer, S. Häfner, T. Syrovets, W. Liu, Y. Tokura, D. Y. W. Ng, A. Riegger, C. Förtsch, D. Jager, T. F. E. Barth, T. Simmet, H. Barth and T. Weil, "Boosting Antitumor Drug Efficacy with Chemically Engineered Multidomain Proteins", Adv Sci (Weinh), vol. 5, no. 8, pp. 1701036, 2018.
DOI:10.1002/advs.201701036
File:https://www.ncbi.nlm.nih.gov/pubmed/30128225
192.
Y. Mödinger, A. Rapp, J. Pazmandi, A. Vikman, K. Holzmann, M. Haffner-Luntzer, M. Huber-Lang and A. Ignatius, "C5aR1 interacts with TLR2 in osteoblasts and stimulates the osteoclast-inducing chemokine CXCL10", J Cell Mol Med, vol. 22, no. 12, pp. 6002-6014, 2018.
DOI:10.1111/jcmm.13873
File:https://onlinelibrary.wiley.com/doi/abs/10.1111/jcmm.13873
191.
V. Fischer, "Calcium and vitamin D in bone fracture healing and post-traumatic bone turnover", Eur Cell Mater, vol. 35, pp. 365-385, 2018.
DOI:10.22203/eCM.v035a25
File:https://www.ncbi.nlm.nih.gov/pubmed/29931664
190.
"Cell-based RNAi screening and high-content analysis in primary calvarian osteoblasts applied to identification of osteoblast differentiation regulators", Sci Rep, vol. 8, no. 1, pp. 14045, 2018.
DOI:10.1038/s41598-018-32364-8
File:https://www.ncbi.nlm.nih.gov/pubmed/30232406
189.
J. U. Werner, K. Todter, P. Xu, L. Lockhart, M. Jahnert, P. Gottmann, A. Schurmann, L. Scheja, M. Wabitsch and U. Knippschild, "Comparison of Fatty Acid and Gene Profiles in Skeletal Muscle in Normal and Obese C57BL/6J Mice before and after Blunt Muscle Injury", Front Physiol, vol. 9, pp. 19, 2018.
DOI:10.3389/fphys.2018.00019
File:https://www.ncbi.nlm.nih.gov/pubmed/29441023
188.
S. Chakraborty and E. Karasu, "Complement After Trauma: Suturing Innate and Adaptive Immunity", Front Immunol, vol. 9, pp. 2050, 2018.
DOI:10.3389/fimmu.2018.02050
File:https://www.ncbi.nlm.nih.gov/pubmed/30319602
187.
D. A. C. Messerer, S. Denk, K. J. Fohr, C. K. Braun, F. Hones, J. Harant, M. Fauler, M. Frick, B. L. Nussbaum, P. Radermacher, S. Häfner and M. S. Huber-Lang, "Complement C5a Alters the Membrane Potential of Neutrophils during Hemorrhagic Shock", Mediators Inflamm, vol. 2018, pp. 2052356, 2018.
DOI:10.1155/2018/2052356
File:https://www.ncbi.nlm.nih.gov/pubmed/30002598
186.
B. Nussbaum, R. Wang, C. Szabo and P. Radermacher, "Cystathionine-gamma-lyase expression is associated with mitochondrial respiration during sepsis-induced acute kidney injury in swine with atherosclerosis", Intensive Care Med Exp, vol. 6, no. 1, pp. 43, 2018.
DOI:10.1186/s40635-018-0208-z
File:https://www.ncbi.nlm.nih.gov/pubmed/30343340
185.
C. Zhang, "Deletion of Menin in craniofacial osteogenic cells in mice elicits development of mandibular ossifying fibroma", Oncogene, vol. 37, no. 5, pp. 616-626, 2018.
DOI:10.1038/onc.2017.364
File:https://www.ncbi.nlm.nih.gov/pubmed/28991228
184.
P. Xu, J. U. Werner, S. Milerski, C. M. Hamp, T. Kuzenko, M. Jahnert, P. Gottmann, L. Roy, D. Warnecke, A. Abaei, A. Palmer, L. Dürselen, V. Rasche, A. Schurmann, M. Wabitsch and U. Knippschild, "Diet-Induced Obesity Affects Muscle Regeneration After Murine Blunt Muscle Trauma-A Broad Spectrum Analysis", Front Physiol, vol. 9, pp. 674, 2018.
DOI:10.3389/fphys.2018.00674
File:https://www.ncbi.nlm.nih.gov/pubmed/29922174
183.
K. Prystaz, K. Kaiser, V. Fischer, A. E. Rapp and G. H. Waetzig, "Distinct Effects of IL-6 Classic and Trans-Signaling in Bone Fracture Healing", Am J Pathol, vol. 188, no. 2, pp. 474-490, 2018.
DOI:10.1016/j.ajpath.2017.10.011
File:https://www.ncbi.nlm.nih.gov/pubmed/29146294
182.
V. Fischer, "Effects of low-magnitude high-frequency vibration on osteoblasts are dependent on estrogen receptor alpha signaling and cytoskeletal remodeling", Biochem Biophys Res Commun, vol. 503, no. 4, pp. 2678-2684, 2018.
DOI:10.1016/j.bbrc.2018.08.023
File:https://www.ncbi.nlm.nih.gov/pubmed/30093109
181.
P. D. Fromm and D. Chen, "Endogenous glucocorticoid signaling in chondrocytes attenuates joint inflammation and damage", FASEB J, vol. 32, no. 1, pp. 478-487, 2018.
DOI:10.1096/fj.201700659R
File:https://www.ncbi.nlm.nih.gov/pubmed/28928247
180.
"Estrogen receptor alpha- (ERalpha), but not ERbeta-signaling, is crucially involved in mechanostimulation of bone fracture healing by whole-body vibration", Bone, vol. 110, pp. 11-20, 2018.
DOI:10.1016/j.bone.2018.01.017
File:https://www.ncbi.nlm.nih.gov/pubmed/29367057
179.
"Glucocorticoid receptor in stromal cells is essential for glucocorticoid-mediated suppression of inflammation in arthritis", Ann Rheum Dis, vol. 77, no. 11, pp. 1610-1618, 2018.
DOI:10.1136/annrheumdis-2017-212762
File:https://www.ncbi.nlm.nih.gov/pubmed/29997111
178.
"Glucocorticoids suppress Wnt16 expression in osteoblasts in vitro and in vivo", Sci Rep, vol. 8, no. 1, pp. 8711, 2018.
DOI:10.1038/s41598-018-26300-z
File:https://www.ncbi.nlm.nih.gov/pubmed/29880826
177.
O. Lesur, E. Delile and P. Radermacher, "Hemodynamic support in the early phase of septic shock: a review of challenges and unanswered questions", Ann Intensive Care, vol. 8, no. 1, pp. 102, 2018.
DOI:10.1186/s13613-018-0449-8
File:https://www.ncbi.nlm.nih.gov/pubmed/30374729
176.
C. K. Braun, S. Denk, B. Mayer, P. Cinelli, P. Radermacher, G. A. Wanner, H. P. Simmen, F. Gebhard and D. Rittirsch, "Hemorrhagic shock drives glycocalyx, barrier and organ dysfunction early after polytrauma", J Crit Care, vol. 44, pp. 229-237, 2018.
DOI:10.1016/j.jcrc.2017.11.025
File:https://www.ncbi.nlm.nih.gov/pubmed/29175047
175.
J. Demiselle, P. Radermacher, F. Schortgen, F. Meziani, M. Singer, V. Seegers and H. S. investigators, "Hyperoxia toxicity in septic shock patients according to the Sepsis-3 criteria: a post hoc analysis of the HYPER2S trial", Ann Intensive Care, vol. 8, no. 1, pp. 90, 2018.
DOI:10.1186/s13613-018-0435-1
File:https://www.ncbi.nlm.nih.gov/pubmed/30225670
174.
M. Mettang, S. N. Reichel, M. Lattke, A. Palmer, A. Abaei, V. Rasche and T. Wirth, "IKK2/NF-kappaB signaling protects neurons after traumatic brain injury", FASEB J, vol. 32, no. 4, pp. 1916-1932, 2018.
DOI:10.1096/fj.201700826R
File:https://www.ncbi.nlm.nih.gov/pubmed/29187362
173.
A. E. Rapp, "Induced global deletion of glucocorticoid receptor impairs fracture healing", FASEB J, vol. 32, no. 4, pp. 2235-2245, 2018.
DOI:10.1096/fj.201700459RR
File:https://www.ncbi.nlm.nih.gov/pubmed/29217668
172.
V. Fischer, M. Kalbitz, F. Muller-Graf and F. Gebhard, "Influence of Menopause on Inflammatory Cytokines during Murine and Human Bone Fracture Healing", Int J Mol Sci, vol. 19, no. 7, pp. 2070, 2018.
DOI:10.3390/ijms19072070
File:https://www.ncbi.nlm.nih.gov/pubmed/30013010
171.
J. D. Lambris and P. A. Ward, "Innate immune responses to trauma", Nat Immunol, vol. 19, no. 4, pp. 327-341, 2018.
DOI:10.1038/s41590-018-0064-8
File:https://www.ncbi.nlm.nih.gov/pubmed/29507356
170.
B. Lukaschewski, A. Rupprecht, M. Whiteman, C. Szabo, R. Wang and P. Radermacher, "Interaction of the hydrogen sulfide system with the oxytocin system in the injured mouse heart", Intensive Care Med Exp, vol. 6, no. 1, pp. 41, 2018.
DOI:10.1186/s40635-018-0207-0
File:https://www.ncbi.nlm.nih.gov/pubmed/30341744
169.
F. Roselli, A. Chandrasekar and M. C. Morganti-Kossmann, "Interferons in Traumatic Brain and Spinal Cord Injury: Current Evidence for Translational Application", Front Neurol, vol. 9, pp. 458, 2018.
DOI:10.3389/fneur.2018.00458
File:pdfhttps://www.ncbi.nlm.nih.gov/pubmed/29971040 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6018073/pdf/fneur-09-00458.pdf
168.
C. Q. Schmidt and C. M. Karsten, "Janus face of complement-driven neutrophil activation during sepsis", Semin Immunol, vol. 37, pp. 12-30, 2018.
DOI:10.1016/j.smim.2018.02.004
File:https://www.sciencedirect.com/science/article/pii/S1044532317301173
167.
K. Singh, E. Camera, L. Krug, A. Basu, R. K. Pandey, S. Munir, M. Wlaschek, S. Kochanek, M. Picardo, C. Niemann, P. Maity and K. Scharffetter-Kochanek, "JunB defines functional and structural integrity of the epidermo-pilosebaceous unit in the skin", Nat Commun, vol. 9, no. 1, pp. 3425, 2018.
DOI:10.1038/s41467-018-05726-z
File:pdfhttps://www.ncbi.nlm.nih.gov/pubmed/30143626 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6109099/pdf/41467_2018_Article_5726.pdf
166.
T. S. Böbel, S. B. Hackl, M. N. Jarczok, N. Rohleder, G. A. Rook, C. A. Lowry, H. Gundel and S. O. Reber, "Less immune activation following social stress in rural vs. urban participants raised with regular or no animal contact, respectively", Proc Natl Acad Sci U S A, vol. 115, no. 20, pp. 5259-5264, 2018.
DOI:10.1073/pnas.1719866115
File:https://www.ncbi.nlm.nih.gov/pubmed/29712842
165.
M. Haffner-Luntzer, A. Kovtun, V. Fischer, K. Prystaz, A. Hainzl, C. M. Kroeger, I. Krikki, T. J. Brinker, A. Ignatius and M. Gatzka, "Loss of p53 compensates osteopenia in murine Mysm1 deficiency", FASEB J, vol. 32, no. 4, pp. 1957-1968, 2018.
DOI:10.1096/fj.201700871R
File:http://www.fasebj.org/content/early/2017/12/01/fj.201700871R.abstract