Projects of the third funding period

Project	Title	PI
A01	Neuro-renal crosstalk as immune-modulator of trauma-related acute kidney injury and MODS	M. Huber-Lang
A02	Modulation of synaptic plasticity after trauma	T. Böckers
A03	Cell type specific modulation of NF-κB in traumatic brain injury	T. Wirth
A05	Cellular and molecular responses to trauma-induced damage of the distal respiratory epithelium	H. Barth M. Frick
A06	Therapeutic targeting of small extracellular vesicle (sEV) release and uptake in post-traumatic hyper-inflammation	T. Seufferlein
A07	Role of myeloid-derived suppressor cells (MDSCs) in post-traumatic and post-septic immune regulation	G. Strauß
A09 N	The role of white adipose tissue in post-traumatic inflammation and organ dysfunction	R. Halbgebauer P. Fischer-Posovszky
B03	Oxytocin and H2S after TBI and hemorrhage with pre-existing early life stress	T. Merz P. Radermacher
B05	Circular RNAs modulate neuronal vulnerability, neuroinflammation and regeneration and are affected by TBI comorbidities	F. Roselli
B06	Effects of early life stress on bone homeostasis and fracture healing	M. Haffner-Luntzer S. Reber
B08	Effects of peripheral and CNS trauma on the brains of healthy and Parkinson ́s Disease mouse models	L. Dimou K. Danzer
B09	Elucidating the pathomechanisms of compromised fracture healing in osteoporosis: Consequences of mitochondrial dysfunction	A. Ignatius J. Riegger-Koch
C02	Osteoblast differentiation-stage specific mechanisms of glucocorticoid action during fracture healing	J. Tuckermann A. Ignatius
C03	Intrinsic heterogeneity and interactions with niches regulate trauma-induced osteoblast dedifferentiation and migration during zebrafish regeneration	G. Weidinger
C05	Role of ABCB5+ MSCs in niche homoeostasis and repair after trauma	K. Scharffetter-Kochanek
C06	Enhancing recovery after traumatic brain injury (TBI) by genetic and pharmacological modulation of the PTEN/Akt pathway	B. Knöll
C08	Glucocorticoids influence Schwann cell and macrophage responses in a mouse model of peripheral nerve injury	S. Vettorazzi S. Meyer zu  Reckendorf
Z01	Central Tasks of the Collaborative Research Centre	F. Gebhard
Z02	Central project for trauma modeling, monitoring and diagnostics	M. Huber-Lang A. Ignatius V. Rasche