2022

Aging-Dependent Altered Transcriptional Programs Underlie Activity Impairments in Human C9orf72-Mutant Motor Neurons
Daniel Sommer, Sandeep Rajkumar, Kerstin Mira Schneider-Seidel, Amr Aly, Albert C. Ludolph, Ritchie
Ho, Tobias M. Boeckers and Alberto Catanese,
Front Mol Neurosci., 2022 June

Epigenetic clocks for mice based on age-associated regions that are conserved between mouse strains and human
Juan Perez-Correa, Vithurithra Tharmapalan, Hartmut Geiger and Wolfgang Wagner , Front Cell Dev
Biol., 2022 June

2023

Multiomics and machine-learning identify novel transcriptional and mutational signatures in amyotrophic lateral sclerosis
Alberto Catanese, Sandeep Rajkumar , Daniel Sommer , Pegah Masrori, Nicole Hersmus, Philip Van
Damme , Simon Witzel, Albert Ludolph , Ritchie Ho, Tobias M Boeckers, Medhanie Mulaw,
Brain., 2023 March

TFIIH mutations can impact on translational fidelity of the ribosome
Fatima Khalid , Tamara Phan, Mingyue Qiang, Pallab Maity, Theresa Lasser, Sebastian Wiese, Marianna Penzo, Marius Alupei,
Donata Orioli, Karin Scharffetter-Kochanek and Sebastian Iben,
Hum Mol Genet., 2023 March

Glucocorticoid activation of anti-inflammatory macrophages protects against insulin resistance
Giorgio Caratti, Ulrich Stifel, Bozhena Caratti, Ali J M Jamil, Kyoung-Jin Chung, Michael
Kiehntopf, Markus H Gräler, Matthias Blüher, Alexander Rauch, Jan P Tuckermann,
Nat Commun., 2023 April

To aggregate or not to aggregate - Is it a matter of the ribosome?
Sebastian Iben
Bioessays., 2023 May

Polymerase iota (Pol ι) prevents PrimPol-mediated nascent DNA synthesis and chromosome instability
Sabrina F Mansilla, Agostina P Bertolin , Sofía Venerus Arbilla, Bryan A Castaño, Tiya Jahjah, Jenny K
Singh , Sebastián O Siri, María Victoria Castro, María Belén de la Vega, Annabel Quinet , Lisa Wiesmüller, Vanesa Gottifredi,
Sci Adv., 2023 June

Impaired ATF3 signaling involves SNAP25 in SOD1 mutant ALS patients
Volkan Yazar, Julia K Kühlwein, Antje Knehr, Veselin Grozdanov, Arif B Ekici , Albert C Ludolph, Karin M Danzer,
Sci Rep., 2023 July

Ribosomal Dysfunction Is a Common Pathomechanism in Different Forms of Trichothiodystrophy.
Zhu G, Khalid F, Zhang D, Cao Z, Maity P, Kestler HA, Orioli D, Scharffetter-Kochanek K, Iben S.,
Cells., 2023 July

Simulating space conditions evokes different DNA damage responses in immature and mature cells of the human Hematopoietic system
Leonie Handwerk, Heike Katrin Schreier, Daniela Kraft, Kateryna Shreder, Ruth Hemmersbach , Jens
Hauslage , Halvard Bonig, Lisa Wiesmüller , Claudia Fournier, Melanie Rall-Scharpf,
Int. J Mol Sci., 2023 September

The skin of the naked mole-rat and its resilience against aging and cancer
Meinhard Wlaschek , Karmveer Singh, Pallab Maity, Karin Scharffetter-Kochanek,
Mech Aeging Dev., 2023 November

2024

Metabolic rewiring promotes anti-inflammatory effects of glucocorticoids
Jean-Philippe Auger, Max Zimmermann, Maria Faas, Ulrich Stifel, David Chambers, Brenda Krishnacoumar, R Verena Taudte , Charlotte Grund , Gitta Erdmann, Carina Scholtysek, Stefan Uderhardt, Oumaima Ben Brahim , Mónica Pascual Maté , Cornelia Stoll , Martin Böttcher , Katrin Palumbo-Zerr, Matthew S J Mangan, Maria Dzamukova , Markus Kieler, Melanie Hofmann, Stephan Blüml, Gernot Schabbauer, Dimitrios Mougiakakos , Uwe Sonnewald , Fabian Hartmann, David Simon , Arnd Kleyer  , Anika Grüneboom, Susetta Finotto, Eicke Latz, Jörg Hofmann, Georg Schett , Jan Tuckermann , Gerhard Krönke,
Nature., 2024 April

Heterozygous knockout of Synaptotagmin13 phenocopies ALS features and TP53 activation in human motor neurons
Johannes Lehmann , Amr Aly , Christina Steffke , Luca Fabbio, Valentin Mayer,  Natalie Dikwella, Kareen Halablab, Francesco Roselli, Simone Seiffert, Tobias M Boeckers , David Brenner, Edor Kabash , Medhanie Mulaw, Ritchie Ho, Alberto Catanese,
Cell Death Dis., 2024 August

Guidelines for minimal information on cellular senescence experimentation in vivo
Mikolaj Ogrodnik, Juan Carlos Acosta, Peter D Adams, Fabrizio d'Adda di Fagagna, Darren J Baker, Cleo L Bishop , Tamir Chandra, Manuel Collado, Jesus Gil, Vassilis Gorgoulis, Florian Gruber , Eiji Hara, Pidder Jansen-Dürr, Diana Jurk , Sundeep Khosla, James L Kirkland, Valery Krizhanovsk , Tohru Minamino, Laura J Niedernhofer , João F Passos, Nadja A R Ring, Heinz Redl, Paul D Robbins, Francis Rodier, Karin Scharffetter-Kochanek, John M Sedivy, Ewa Sikora , Kenneth Witwer, Thomas von Zglinicki , Maximina H Yun, Johannes Grillari, Marco Demaria,
Cell., 2024 August