SFB 1149
Zusammenstellung von Bildern aus dem Sonderforschungsbereich

Publikationen aus dem SFB 1149

2023

414.
C. Hilbrig, J. Löffler, G. Fischer, E. Scheidhauer, C. Solbach, A. J. Beer, V. Rasche and G. Winter, "Evaluation of the EPR Effect in the CAM-Model by Molecular Imaging with MRI and PET Using (89)Zr-Labeled HSA", Cancers (Basel), vol. 15, no. 4, 2023.
DOI:10.3390/cancers15041126
Datei:https://www.ncbi.nlm.nih.gov/pubmed/36831469
413.
M. Amoroso, E. Kempter, M. Kustermann, J. Scheurer, C. A. Lowry and S. O. Reber, "Mycobacterium vaccae protects against glucocorticoid resistance resulting from combined physical and psychosocial trauma in mice", Brain Behav Immun, 2023.
DOI:10.1016/j.bbi.2023.01.018
Datei:https://www.ncbi.nlm.nih.gov/pubmed/36736929

2022 in press (preprint)

412.
I. Sehring, M. Haffner-Luntzer, A. Ignatius, M. Huber-Lang and G. Weidinger, "Zebrafish fin regeneration requires generic and regeneration-specific responses of osteoblasts to trauma", bioRxiv, 2022 in press (preprint).
DOI:10.1101/2022.02.22.481466

2022

411.
A. Loft, S. F. Schmidt, U. Stifel, J. Havelund, R. Sekar, Y. Kwon, A. Sulaj, K. K. Chow, A. J. Alfaro, T. Schwarzmayr, N. Rittig, M. Svart, F. F. Tsokanos, A. Maida, A. Blutke, A. Feuchtinger, N. Moller, P. Nawroth, J. Szendrodi, N. J. Faergeman and A. Zeigerer, "A macrophage-hepatocyte glucocorticoid receptor axis coordinates fasting ketogenesis", Cell Metab, vol. 34, no. 3, pp. 473-486 e9, 2022.
DOI:10.1016/j.cmet.2022.01.004
Datei:https://www.ncbi.nlm.nih.gov/pubmed/35120589
410.
M. E. A. Tschaffon, S. O. Reber, A. Schoppa and A. Aszodi, "A novel in vitro assay to study chondrocyte-to-osteoblast transdifferentiation", Endocrine, vol. 75, no. 1, pp. 266-275, 2022.
DOI:10.1007/s12020-021-02853-4
Datei:https://www.ncbi.nlm.nih.gov/pubmed/34529238
409.
L. Wrba, J. Roos and P. Fischer-Posovszky, "Adipose tissue: a neglected organ in the response to severe trauma?", Cell Mol Life Sci, vol. 79, no. 4, pp. 207, 2022.
DOI:10.1007/s00018-022-04234-0
Datei:https://www.ncbi.nlm.nih.gov/pubmed/35338424
408.
M. Kustermann, P. Dasari, I. Knape, E. Keltsch, S. Pflüger, W. Osen, K. Holzmann and K. M. Debatin, "Adoptively Transferred in vitro-Generated Myeloid-Derived Suppressor Cells Improve T-Cell Function and Antigen-Specific Immunity after Traumatic Lung Injury", J Innate Immun, pp. 1-18, 2022.
DOI:10.1159/000525088
Datei:https://www.ncbi.nlm.nih.gov/pubmed/35691281
407.
A. Kerstan, K. Dieter, E. Niebergall-Roth, A. K. Dachtler, K. Kraft, M. Stucker, G. Daeschlein, M. Junger, T. Gorge, U. Meyer-Pannwitt, C. Erfurt-Berge, C. Engelhardt, A. Klare, C. Pfeiffer, J. Esterlechner, H. M. Schroder, M. Gasser, A. M. Waaga-Gasser, M. Goebeler, S. Ballikaya, S. Sadeghi, G. F. Murphy, D. P. Orgill, N. Y. Frank, C. Ganss, K. Scharffetter-Kochanek, M. H. Frank and M. A. Kluth, "Allogeneic ABCB5(+) mesenchymal stem cells for treatment-refractory chronic venous ulcers: a phase I/IIa clinical trial", JID Innov, vol. 2, no. 1, 2022.
DOI:10.1016/j.xjidi.2021.100067
Datei:https://www.ncbi.nlm.nih.gov/pubmed/34870260
406.
A. M. Eickhoff, R. Cintean, C. Fiedler, F. Gebhard, K. Schutze and P. H. Richter, "Analysis of partial weight bearing after surgical treatment in patients with injuries of the lower extremity", Arch Orthop Trauma Surg, vol. 142, no. 1, pp. 77-81, 2022.
DOI:10.1007/s00402-020-03588-z
Datei:https://www.ncbi.nlm.nih.gov/pubmed/32880704
405.
K. Singh, P. Maity, A. K. Koroma, A. Basu, R. K. Pandey, S. Vander Beken, P. Haas, L. Krug, A. Hainzl, A. Sindrilaru, C. Pfeiffer, M. Wlaschek, N. Y. Frank, M. H. Frank, C. Ganss, A. Banvolgyi, N. Wikonkal, S. Eming, I. Pastar, M. Tomic-Canic, M. A. Kluth and K. Scharffetter-Kochanek, "Angiogenin Released from ABCB5(+) Stromal Precursors Improves Healing of Diabetic Wounds by Promoting Angiogenesis", J Invest Dermatol, vol. 142, no. 6, pp. 1725-1736 e10, 2022.
DOI:10.1016/j.jid.2021.10.026
Datei:https://www.ncbi.nlm.nih.gov/pubmed/34808236
404.
J. Bülow, J. Tuckermann, A. Ignatius and M. Haffner-Luntzer, "Bone Mass and Osteoblast Activity Are Sex-Dependent in Mice Lacking the Estrogen Receptor & in Chondrocytes and Osteoblast Progenitor Cells", International Journal of Molecular Sciences, vol. 23, no. 5, pp. 2902, 2022.
DOI:doi:10.3390/ijms23052902
Datei:https://www.mdpi.com/1422-0067/23/5/2902
403.
T. Kapapa, A. Hoffmann, H. Gundel, C. Szabo and P. Radermacher, "Brain Histology and Immunohistochemistry After Resuscitation From Hemorrhagic Shock in Swine With Pre-Existing Atherosclerosis and Sodium Thiosulfate (Na(2)S(2)O(3)) Treatment", Front Med (Lausanne), vol. 9, pp. 925433, 2022.
DOI:10.3389/fmed.2022.925433
Datei:https://www.ncbi.nlm.nih.gov/pubmed/35847799
402.
P. Dietl and M. Frick, "Channels and Transporters of the Pulmonary Lamellar Body in Health and Disease", Cells, vol. 11, no. 1, pp. 45, 2022.
DOI:10.3390/cells11010045
Datei:https://www.ncbi.nlm.nih.gov/pubmed/35011607
401.
J. M. Preuss, C. Tilp, M. Keck, J. Blender, U. Wachter, A. Hoffmann and P. Radermacher, "Cigarette smoke exposure reduces hemorrhagic shock induced circulatory dysfunction in mice with attenuated glucocorticoid receptor function", Front Immunol, vol. 13, pp. 980707, 2022.
DOI:10.3389/fimmu.2022.980707
Datei:https://www.ncbi.nlm.nih.gov/pubmed/36172380
400.
S. Lee, A. Ignatius and J. Tuckermann, "Distinct Glucocorticoid Receptor Actions in Bone Homeostasis and Bone Diseases", Frontiers in Endocrinology, vol. 12, pp. 1887, 2022.
DOI:10.3389/fendo.2021.815386
Datei:https://www.frontiersin.org/article/10.3389/fendo.2021.815386
399.
M. Hogg, E. Abdelsalam, A. Hoffmann, V. Saub, E. M. Wolfschmitt, U. Wachter, J. A. Vogt, R. Wang, P. Radermacher and B. L. Nussbaum, "Effects of Sodium Thiosulfate During Resuscitation from Trauma-and-Hemorrhage in Cystathionine gamma-Lyase (CSE) Knockout Mice", Shock, vol. 57, no. 1, pp. 131-139, 2022.
DOI:10.1097/SHK.0000000000001828
Datei:https://www.ncbi.nlm.nih.gov/pubmed/34172609
398.
M. Hogg, E. Abdelsalam, A. Hoffmann, U. Wachter, J. A. Vogt, R. Wang and P. Radermacher, "Effects of Sodium Thiosulfate During Resuscitation From Trauma-and-Hemorrhage in Cystathionine-gamma-Lyase Knockout Mice With Diabetes Type 1", Front Med (Lausanne), vol. 9, pp. 878823, 2022.
DOI:10.3389/fmed.2022.878823
Datei:https://www.ncbi.nlm.nih.gov/pubmed/35572988
397.
U. Stifel, E. M. Wolfschmitt, U. Wachter, D. Tews, M. Hogg, F. Zink, N. M. Koll, S. Winning, P. Radermacher and P. Fischer-Posovszky, "Glucocorticoids coordinate macrophage metabolism through the regulation of the tricarboxylic acid cycle", Mol Metab, vol. 57, pp. 101424, 2022.
DOI:10.1016/j.molmet.2021.101424
Datei:https://www.ncbi.nlm.nih.gov/pubmed/34954109
396.
C. Brucker and P. Radermacher, "H(2)S in Critical Illness-A New Horizon for Sodium Thiosulfate?", Biomolecules, vol. 12, no. 4, 2022.
DOI:10.3390/biom12040543
Datei:https://www.ncbi.nlm.nih.gov/pubmed/35454132
395.
J. M. Preuss, "Impaired Glucocorticoid Receptor Signaling Aggravates Lung Injury after Hemorrhagic Shock", Cells, vol. 11, no. 1, pp. 112, 2022.
DOI:10.3390/cells11010112
Datei:https://www.ncbi.nlm.nih.gov/pubmed/35011674
394.
V. Kirsch, J. Ramge, A. Schoppa, A. Ignatius and J. Riegger, "In Vitro Characterization of Doxorubicin-Mediated Stress-Induced Premature Senescence in Human Chondrocytes", Cells, vol. 11, no. 7, pp. 1106, 2022.
DOI:10.3390/cells11071106
393.
Y. Lai, G. Fois, J. R. Flores, M. J. Tuvim, Q. Zhou, J. Leitz, J. Peters, R. A. Pfuetzner, L. Esquivies, P. Jones, M. Frick, B. F. Dickey and A. T. Brunger, "Inhibition of calcium-triggered secretion by hydrocarbon-stapled peptides", Nature, vol. 603, no. 7903, pp. 949-956, 2022.
DOI:10.1038/s41586-022-04543-1
Datei:https://www.ncbi.nlm.nih.gov/pubmed/35322233
392.
M. Haffner-Luntzer, S. Lee, A. Dorn, A. Ignatius, J. Tuckermann and M. Ahmad, "Inhibition of Cdk5 Ameliorates Skeletal Bone Loss in Glucocorticoid-Treated Mice", Biomedicines, vol. 10, no. 2, pp. 404, 2022.
DOI:10.3390/biomedicines10020404
Datei:https://www.mdpi.com/2227-9059/10/2/404
391.
A. K. Dorn, M. Stolz, N. K. Tangudu, D. C. Vazquez, J. Pachmayr and M. V. Spasic, "Inhibition of Cdk5 increases osteoblast differentiation and bone mass and improves fracture healing", Bone Research, vol. 10, no. 1, pp. 33, 2022.
DOI:ARTN 33 10.1038/s41413-022-00195-z
Datei:
390.
V. Fischer, "Interaction between bone and immune cells: Implications for postmenopausal osteoporosis", Semin Cell Dev Biol, vol. 123, pp. 14-21, 2022.
DOI:10.1016/j.semcdb.2021.05.014
Datei:https://www.ncbi.nlm.nih.gov/pubmed/34024716
389.
V. Fischer, D. Ragipoglu, J. Diedrich, L. Steppe, K. Schutze, M. Kalbitz and F. Gebhard, "Mast Cells Trigger Disturbed Bone Healing in Osteoporotic Mice", J Bone Miner Res, vol. 37, no. 1, pp. 137-151, 2022.
DOI:10.1002/jbmr.4455
Datei:https://www.ncbi.nlm.nih.gov/pubmed/34633111
388.
S. Meyer Zu Reckendorf, D. Moser, A. Blechschmidt, V. N. Joga, D. Sinske, J. Hegler, S. Deininger, A. Catanese, G. Antoniadis, T. Boeckers and B. Knöll, "Motoneuron-Specific PTEN Deletion in Mice Induces Neuronal Hypertrophy and Also Regeneration after Facial Nerve Injury", J Neurosci, vol. 42, no. 12, pp. 2474-2491, 2022.
DOI:10.1523/JNEUROSCI.1305-21.2022
Datei:https://www.ncbi.nlm.nih.gov/pubmed/35149515
387.
J. Bernhardi and L. Dimou, "Oligodendrogenesis is a key process for cognitive performance improvement induced by voluntary physical activity", Glia, vol. 70, no. 6, pp. 1052-1067, 2022.
DOI:10.1002/glia.24155
Datei:https://www.ncbi.nlm.nih.gov/pubmed/35104015
386.
A. Gihring, M. Schirmer, M. Wabitsch and U. Knippschild, "Recent Developments in Mouse Trauma Research Models: A Mini-Review", Front Physiol, vol. 13, pp. 866617, 2022.
DOI:10.3389/fphys.2022.866617
Datei:https://www.ncbi.nlm.nih.gov/pubmed/35574493
385.
D. A. C. Messerer, F. Munz, A. Hoffmann, R. Mathieu, S. Mayer, H. Gassler, F. Zink, E. M. Wolfschmitt, T. Thebrath, S. Zuech, P. Radermacher and T. Kapapa, "The effect of targeted hyperoxemia in a randomized controlled trial employing a long-term resuscitated, model of combined acute subdural hematoma and hemorrhagic shock in swine with coronary artery disease: An exploratory, hypothesis-generating study", Front Med (Lausanne), vol. 9, pp. 971882, 2022.
DOI:10.3389/fmed.2022.971882
Datei:https://www.ncbi.nlm.nih.gov/pubmed/36072939
384.
I. M. Sehring, "The fin roundabout: Slit-Robo and S1P signaling coordinate fin morphogenesis", EMBO Rep, vol. 23, no. 8, pp. e55563, 2022.
DOI:10.15252/embr.202255563
Datei:https://www.ncbi.nlm.nih.gov/pubmed/35836403
383.
D. A. C. Messerer, H. Gaessler, A. Hoffmann, K. Benz, A. Huhn, F. Hezel and P. Radermacher, "The H(2)S Donor Sodium Thiosulfate (Na(2)S(2)O(3)) Does Not Improve Inflammation and Organ Damage After Hemorrhagic Shock in Cardiovascular Healthy Swine", Front Immunol, vol. 13, pp. 901005, 2022.
DOI:10.3389/fimmu.2022.901005
Datei:https://www.ncbi.nlm.nih.gov/pubmed/35784322
382.
J. Eisele, S. Schreiner, J. Borho, S. Fischer, S. Heber, S. Endres, M. Fellermann, L. Wohlgemuth, G. Fois, M. Fauler, M. Frick and H. Barth, "The Pore-Forming Subunit C2IIa of the Binary Clostridium botulinum C2 Toxin Reduces the Chemotactic Translocation of Human Polymorphonuclear Leukocytes", Front Pharmacol, vol. 13, pp. 810611, 2022.
DOI:10.3389/fphar.2022.810611
Datei:https://www.ncbi.nlm.nih.gov/pubmed/35222028
381.
A. Kerstan, K. Dieter, E. Niebergall-Roth, S. Klingele, M. Junger, C. Hasslacher, G. Daeschlein, L. Stemler, U. Meyer-Pannwitt, K. Schubert, G. Klausmann, T. Raab, M. Goebeler, K. Kraft, J. Esterlechner, H. M. Schroder, S. Sadeghi, S. Ballikaya, M. Gasser, A. M. Waaga-Gasser, G. F. Murphy, D. P. Orgill, N. Y. Frank, C. Ganss, K. Scharffetter-Kochanek, M. H. Frank and M. A. Kluth, "Translational development of ABCB5(+) dermal mesenchymal stem cells for therapeutic induction of angiogenesis in non-healing diabetic foot ulcers", Stem Cell Res Ther, vol. 13, no. 1, pp. 455, 2022.
DOI:10.1186/s13287-022-03156-9
Datei:https://www.ncbi.nlm.nih.gov/pubmed/36064604
380.
A. Bertozzi, C. C. Wu, S. Hans and M. Brand, "Wnt/beta-catenin signaling acts cell-autonomously to promote cardiomyocyte regeneration in the zebrafish heart", Dev Biol, vol. 481, pp. 226-237, 2022.
DOI:10.1016/j.ydbio.2021.11.001
Datei:https://www.ncbi.nlm.nih.gov/pubmed/34748730
379.
I. Sehring and H. F. Mohammadi, "Zebrafish fin regeneration involves generic and regeneration-specific osteoblast injury responses", Elife, vol. 11, 2022.
DOI:10.7554/eLife.77614
Datei:https://www.ncbi.nlm.nih.gov/pubmed/35748539
378.
A. K. Sauer, S. Malijauskaite, P. Meleady, T. M. Boeckers, K. McGourty and A. M. Grabrucker, "Zinc is a key regulator of gastrointestinal development, microbiota composition and inflammation with relevance for autism spectrum disorders", Cellular and Molecular Life Sciences, vol. 79, no. 1, pp. 18, 2022.
DOI:10.1007/s00018-021-04052-w
Datei:pdf

2021 in press

377.
U. Stifel, E. M. Wolfschmitt, U. Wachter, D. Tews, M. Hogg, F. Zink, N. M. Koll, S. Winning, P. Radermacher and P. Fischer-Posovszky, "Glucocorticoids Coordinate Macrophage Metabolism Through Regulation of the Tricarboxylic Acid Cycle", Mol Metab, pp. 101424, 2021 in press.
DOI:10.1016/j.molmet.2021.101424
Datei:https://www.ncbi.nlm.nih.gov/pubmed/34954109

2021 accepted

376.
A. I. Mubashir Ahmad and J. Tuckermann., " Inhibition of Cdk5 increases osteoblast differentiation and bone mass and improves fracture healing ", Bone Research, 2021 accepted.

2021

375.
C. Leinert, S. Brefka, U. Braisch, N. Denninger, M. Mueller, P. Benzinger, J. Bauer, A. Bahrmann, N. Frey, T. Geisler, G. Eschweiler, J. Klaus, K. Schuetze, F. Gebhard, J. Dreyhaupt, R. Muche, K. Pahmeier, J. Biermann-Stallwitz, J. Wasem, L. Flagmeier, D. Dallmeier and M. Denkinger, "A complex intervention to promote prevention of delirium in older adults by targeting caregiver's participation during and after hospital discharge - study protocol of the TRAnsport and DElirium in older people (TRADE) project", BMC Geriatr, vol. 21, no. 1, pp. 646, 2021.
DOI:10.1186/s12877-021-02585-0
Datei:pdfhttps://www.ncbi.nlm.nih.gov/pubmed/34784883 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8594294/pdf/12877_2021_Article_2585.pdf
374.
S. Cursano, C. R. Battaglia, C. Urrutia-Ruiz, S. Grabrucker, M. Schon, J. Bockmann, S. Braumuller, P. Radermacher, F. Roselli and T. M. Boeckers, "A CRHR1 antagonist prevents synaptic loss and memory deficits in a trauma-induced delirium-like syndrome", Mol Psychiatry, vol. 26, no. 8, pp. 3778-3794, 2021.
DOI:10.1038/s41380-020-0659-y
Datei:pdfhttps://www.ncbi.nlm.nih.gov/pubmed/32051550 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8550963/pdf/41380_2020_Article_659.pdf
373.
J. C. M. Gebhardt, "A guide to changing paradigms of glucocorticoid receptor function-a model system for genome regulation and physiology", FEBS J, 2021.
DOI:10.1111/febs.16100
Datei:https://www.ncbi.nlm.nih.gov/pubmed/34213830
372.
P. H. Richter, A. Blidon, A. Eickhoff, F. Gebhard and K. Schuetze, "Accuracy of screw stabilization of the dorsal pelvic ring using a hybrid operating room: 5 Year experience in a level 1 trauma center", Injury, vol. 52, no. 10, pp. 2968-2972, 2021.
DOI:10.1016/j.injury.2021.06.024
Datei:https://www.ncbi.nlm.nih.gov/pubmed/34275645
371.
S. Hug, S. Bernhard, A. E. P. Stratmann, M. Erber, L. Wohlgemuth, C. L. Knapp, J. M. Bauer, L. Vidoni, M. Fauler, K. J. Fohr, P. Radermacher, A. Hoffmann and D. A. C. Messerer, "Activation of Neutrophil Granulocytes by Platelet-Activating Factor Is Impaired During Experimental Sepsis", Front Immunol, vol. 12, pp. 642867, 2021.
DOI:10.3389/fimmu.2021.642867
Datei:pdfhttps://www.ncbi.nlm.nih.gov/pubmed/33796110 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8007865/pdf/fimmu-12-642867.pdf
370.
S. Grabrucker, J. Pagano, J. Schweizer, C. Urrutia-Ruiz, M. Schon, K. Thome, G. Ehret, A. M. Grabrucker, R. Zhang, B. Hengerer, J. Bockmann, C. Verpelli, C. Sala and T. M. Boeckers, "Activation of the medial preoptic area (MPOA) ameliorates loss of maternal behavior in a Shank2 mouse model for autism", Embo Journal, vol. 40, no. 5, pp. 19, 2021.
DOI:10.15252/embj.2019104267
Datei:
369.
R. Rehman, L. Tar, A. J. Olamide, Z. Li, J. Kassubek, T. Böckers, J. Weishaupt, A. Ludolph, D. Wiesner and F. Roselli, "Acute TBK1/IKK-epsilon Inhibition Enhances the Generation of Disease-Associated Microglia-Like Phenotype Upon Cortical Stab-Wound Injury", Front Aging Neurosci, vol. 13, pp. 684171, 2021.
DOI:10.3389/fnagi.2021.684171
Datei:pdfhttps://www.ncbi.nlm.nih.gov/pubmed/34326766 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8313992/pdf/fnagi-13-684171.pdf
367.
P. Radermacher and T. Kapapa, "Biological Connection of Psychological Stress and Polytrauma under Intensive Care: The Role of Oxytocin and Hydrogen Sulfide", Int J Mol Sci, vol. 22, no. 17, pp. 9192, 2021.
DOI:10.3390/ijms22179192
Datei:pdfhttps://www.ncbi.nlm.nih.gov/pubmed/34502097 https://mdpi-res.com/d_attachment/ijms/ijms-22-09192/article_deploy/ijms-22-09192-v2.pdf
366.
E. Kempter, M. Amoroso, H. L. Duffner, A. M. Werner, S. Kupfer and S. O. Reber, "Changes in Functional Glucocorticoid Sensitivity of Isolated Splenocytes Induced by Chronic Psychosocial Stress - A Time Course Study", Front Immunol, vol. 12, pp. 753822, 2021.
DOI:10.3389/fimmu.2021.753822
Datei:pdfhttps://www.ncbi.nlm.nih.gov/pubmed/34675935 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8523951/pdf/fimmu-12-753822.pdf
365.
K. Ernst, M. Landenberger, J. Nieland, K. Norgaard, M. Frick, G. Fois, R. Benz and H. Barth, "Characterization and Pharmacological Inhibition of the Pore-Forming Clostridioides difficile CDTb Toxin", Toxins (Basel), vol. 13, no. 6, pp. 390, 2021.
DOI:10.3390/toxins13060390
Datei:pdfhttps://www.ncbi.nlm.nih.gov/pubmed/34071730 https://mdpi-res.com/d_attachment/toxins/toxins-13-00390/article_deploy/toxins-13-00390-v2.pdf